[Intensive prenatal diagnosis in HIV seropositivity is obsolete. Prenatal care--labor--puerperium].
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Biomedical subjects
Publications and source records attributed to H J Woraschk.
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We performed a study in Doppler sonography in pregnant patients with hypotension compared with women in pregnancy with normal blood pressure. The flow was measured in the foetal aorta, the umbilical artery such as in the A. arcuate and A. cerebri media. Low blood pressure is followed by decreased uteroplacental perfusion. That means a haemodynamic danger for the foetus reflected in significantly increased flow parameters. The low central flow indices show a centralisation of the foetal blood circulating system. These findings describe the importance of hypotension as a risk of pregnancy we have to observe carefully.
During pregnancy application of prostaglandins has been proved a successful method both for induction of midtrimester artificial abortion and cervical priming before termination of pregnancy at the end of first trimester. A report is given about three cases of cervical complications following the induction of artificial abortion and cervical priming with the consequence of operations. Therefore cervical priming should not be considered as an intervention without side effects and complications. It is indicated only in cases of primipregnancy with an unfavourable state of the cervical anatomy and at the end of first trimester.
The influence of atropine sulphate (0.01 mg/kg body weight of pregnant women i.v.) on several parameters of fetal heart rate was investigated with automatic analysis of FHR. Fetal movements were counted, too. After administration of atropine, there was a first period with an "inverse" effect of atropine in all fetuses: decrease in baseline FHR (5.1%, minimum after 4.5 min) and increase in the amplitude of FHR fluctuation (44.6%). Thereafter, in a second period the "true" atropine effect appeared: increase in baseline FHR (15.5% above the level before atropine maximum after 25.1 min) and decrease in the amplitude of fluctuation (64.5%). In the third period baseline FHR returned to normal values but the amplitude of FHR fluctuation as well as the beat-to-beat irregularity remained small in 12 from 14 fetuses. Fetal movements registered by the mothers decreased significantly in this time. The results demonstrate a dualistic effect of atropine in the fetus. Moreover, the amplitude of FHR fluctuation (amplitude of macrofluctuation) and the beat-to-beat irregularity (microfluctuation) changed in an equal manner and appear to be influenced by similar regulatory processes. The divergence in the reaction of the baseline FHR and the amplitude of fluctuation together with a decrease in fetal movements might be caused by a central nervous effect with a change in the behaviour of the fetus.
An off-line computer analysis of antenatal cardiotocograms has been developed. The fetal heart period (interbeat interval), the signals from uterine contractions and fetal movements, the maternal heart period and the continuous time are recorded on magnetic tape. A marking of single steps and of special events during this investigation is possible. For data processing the sequence of measuring values must be divided in shorter intervals (as a rule with a length of 30 seconds).--After this the mean value of FHR and of MHR is calculated for each interval. By computation of the standard deviation (S), the index of instantaneous arrhythmia (IAI), and the number of macrofluctuations of these intervals a quantification of the heart rate short-time-variability and long-time-variability can be performed.
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219 partogramms of primipares and 219 partogramms of multipares were analysed retrospectively. Only normal deliveries after normal pregnancies were taken into consideration. Graphs were plotted of time intervalls against the width of the cervix. The mean duration of dilation were 6 hours for multipares and 9 hours for primipares. All phases of first stage of labour were reduced in multipares. The results were compared with observations of other authors.
Observations on heart frequency during the perinatal period. Registrations of the fetal heart rate were carried out on 133 children before and after delivery. 3 different types of heart rate patterns were found, each of them could be subdivided in 2 groups. The several groups are different in the shape and the steepness of fetal heart rate ascent after delivery. Supplementary other fetal parameters were examined (Apgar-score, time of the first breath, moment of first newborn cry, onset of regular respiration). These parameters showed significant associations with the above-mentioned types of the fetal heart rate patterns. For the blood gas parameters however such relations to the heart rate patterns were not found.
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The isolated endometriosis is a rare sickness whose existence is little thought of although it shows relative specific symptoms. With the aid of literature -- survey and according to personal experience on two patients suffering from isolated endometriosis of ileumregion, were clinical treatments carried out. Surgical and hormonal treatments as well as combination of both, have special indications for this kind of sickness.
Report on 60 patients with induction of labour by intravenous infusion of prostaglandin F2alpha. The high rate of success (95%) was attributed to some favourable factors. Side effects were minimal. Moreover no effects on the metabolism were observed. During labour a electronical and biochemical supervision is neccessary.
Conform to its reaction, prostin F2alpha is a useful medicament above all in order to initiate risky deliveries having a state of unripe cervix. We have estimated the labor pains and the fetal state, which did not give proofs for any negative influence by prostin F2alpha in 60 initiations of labor. An intensive supervision system is absolutely necessary.
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