PubMed HealthSearch

Biomedical subjects

H Johnson

Publications and source records attributed to H Johnson.

13 recordsLinked to original sources

The effectiveness of pediatric nurse associates as clinical instructors of medical students.

Pediatric nurse associates (PNAs) have provided health care services for children, taught physical diagnosis to first-year medical students, and acted as role models for students and residents. Their role as clinical instructors has not been measured objectively. This study evaluated the effect of PNA interaction with medical students in a pediatric clerkship. Students taught by PNAs had higher gains in factual knowledge and greater skills in physical examination as measured by a videotape of a patient encounter. The PNAs demonstrated that they can be effective instructors of medical students.

Clinical Competence

4-Aminoimidazole-5-carboxamide excretion in acute leukemia.

The urinary excretion of 4-aminimidazole-5-carboxamide (AIC) as been reported to be increased in children with acute leukemia and has been correlated with disease status. Using a modification of the method of Skibba et al [5], determinations were made on urine from 26 children with acute leukemia. The urine from ten normal children served as controls. The effect of chemotherapy on urinary AIC was studied comparing patients on vincristine and prednisone (V+P) with those on 6-mercaptopurine, methotrexate, and cyclophosphamide (Triple Rx). Patients in remission on Triple Rx had lower levels of urinary AIC than did patients on Triple Rx in relapse or patients on V+P in either remission or relapse. Twenty patients had sequential measurements. Values for individual patients were not predictive of disease status. One such patient is described. This study demonstrates that chemotherapy, as well as disease status, affects the urinary excretion of AIC in children with acute leukemia.

Acute Disease