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Biomedical subjects

H Junger

Publications and source records attributed to H Junger.

34 records · Page 2Linked to original sources
PubMed1976

[Intraoperative autotransfusion in gynecology and surgery (author's transl)].

The technique of intraoperative autotransfusion (AT) is being used to date only in a few individual clinics. Since there is a clinically safe and economical AT-apparatus available the routine application of this rational blood replacement method is easy to perform. The authors have used this technique altogether in 111 patients, applying the Bentley-ATS-machine in the last 69 cases. In a previous series of 42 cases AT was used for ruptured ectopic pregnancy, in the series of 69 surgical cases for hemothorax or intraabdominal hemorrhages of mainly traumatic origin. The most frequent indications for AT in emergency surgical operations were ruptures of spleen and liver, and in elective surgery for portocaval shunt. Altogether 247 litres of blood have been retransfused with an AT-volume per patient ranging from 0,5 to 15 litres. For anticoagulation generally ACD was used, only in vascular surgery was heparin preferred. Methodical complications have not been seen. Technique, indications, consequences and possible complications of AT are described. The main advantages of autologous intraoperative transfusion are the immediate availability of blood, the absence of the risk of hepatitis and of incompatibility reactions, reduction of pressure on the blood banks and lower transfusion costs. The authors therefore believe that the possibility of intraoperative AT should exist at every surgical and gynecological clinic.

Abdominal Injuries↗
PubMed1976

[Changes in 2,3-diphosphoglycerate Levels in Blood and Brain Tissue after Craniocerebral Trauma and Cardiac Surgery].

The response of the 2,3-diphosphoglycerate (DPG) levels in the blood and brain tissue to a craniocerebral trauma of varying severity was studied in anaesthetized rats. A trauma producing cerebral contusion was followed within two hours by a highly significant rise in DPG concentration in the blood as compared with the control animals or only mildly traumatized rats. The DPG levels in the brain tissue showed no significant differences. Similar changes in DPG concentration were observed in the blood of patients with craniocerebral injuries. The DPG-mediated increased release of oxygen to the tissues represents a compensatory mechanism and is pathognomic for craniocerebral trauma. Patients undergoing surgery with extracorporeal circulation lack this mechanism for counteracting hypoxaemia; already during thoracotomy the DPG concentration in the blood fell significantly and did not reach its original level until 72 hours after the operation. In stored, ACD stabilized, blood the DPG concentration gradually decreases. Estimations carried out over 28 days showed a continuous statistically significant loss of DPG. After 24 hours the DPG levels in stored blood had already dropped to the lower limits of normal - a fact that has to be taken into account in massive blood transfusions.

Adult↗
PubMed1975

[Clinical investigations of the temperature effects of ketamine and halothane in children (author's transl)].

In 68 from 1- to 14-years-old children rectal temperature was measured in Ketamine and Halothane anesthesia and with room temperatures ranging from 22-25 and 26-28 degree centigrade, while orthopedic repair operations were performed on the extremities. Independent of the quality of the premedication, which consisted either of Ketamine (Atropine or Thalamonal) Atropine a significant rise in temperature of 0,4 to 0,5 degrees C. was found within one hour of Ketamine anesthesia, but only with room temperatures of 26-28 degrees C., while with lower room temperatures (22-25 degrees C.) rectal temperature remained unchanged. The rise in temperature occurred both in Ketamine monoanesthesia with spontaneous respiration and in Ketamine-N2O-O2 anesthesia with respiration controlled.

Adolescent↗