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Biomedical subjects

H K Basu

Publications and source records attributed to H K Basu.

13 recordsLinked to original sources

The role of amniotomy in induction of labour with oral administration of prostaglandin E2.

Prostaglandin E2 was administered orally in doses of 0.5 mg. to 2.0 mg. every 2 hours to 169 women for induction of labour. Induction was successful in 153 women (90%). In 99 of these women, low amniotomy was performed at the beginning. Performance of amniotomy at the beginning of induction did not alter the incidence of successful induction but did lead to a mean induction-delivery interval shorter than that in women who had amniotomy performed in the active phase of labour. Vomiting and/or diarrhoea occurred in 34 women (20%). Uterine hypertonus of only transient nature occurred in 3 women. One woman suffered from atonic post-partum haemorrhage. No adverse effects on the fetus were apparent. The presence of fetopelvic disproportion was associated with a slow rate of cervical dilatation and unsuccessful induction.

Administration, Oral

Fibrin degradation products in sera of women with normal menstruation and menorrhagia.

Serum concentrations of fibrin degradation products were found to be higher during menstruation than in the intermenstrual phase. Higher concentrations were present in cases of menorrhagia as compared with healthy women and women with various gynaecological disorders but with normal menstrual function. Higher serum concentrations of fibrin degradation products in cases of menorrhagia may indicate increased local fibrinolytic activity in the uterus.

Adolescent