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Biomedical subjects

H K Tewari

Publications and source records attributed to H K Tewari.

At least 19 recordsLinked to original sources

Bilateral branch vein occlusion.

Bilateral branch retinal vein occlusion is a relatively rare occurrence. We report 4 patients who presented with bilateral branch retinal vein occlusion and in each of these cases the fellow eyes were involved within 6 months of the initial episode. The patients were relatively young and all of them had associated essential hypertension. The patients maintained a relatively good visual acuity through a 6-months to 1-year follow-up. This report highlights this rare entity, the associated risk factors and visual prognosis.

Adult

Peribulbar anesthesia in retinal reattachment surgery.

We prospectively evaluated the effectiveness of peribulbar anesthesia in retinal reattachment surgery. Of the 24 patients studied, 2 required retrobulbar supplementation during the latter part of the surgery. Our results show that peribulbar anesthesia can be effectively used for retinal reattachment surgery and probably should be the preferred form of local anesthesia for this surgery, since the eyes involved have a relatively high incidence of axial myopia and posterior staphyloma.

Adult

Sudden vision loss following retinal detachment surgery.

A 22-year-old man with Eales' disease with secondary rhegmatogenous retinal detachment with a break five disc diameters from the disc underwent radial scleral buckling using a silicone sponge episcleral explant with local cryopexy. Five hours after surgery the patient had no light perception. There was no intraoperative or postoperative rise of intraocular pressure or central retinal artery ischemia. Immediate removal of the explant brought a return of light perception and postoperative visual acuity improvement. The episcleral explant may have caused the direct optic nerve trauma that resulted in loss of vision.

Adult

Ultrasonography in optic nerve head avulsion.

The diagnosis of post traumatic optic nerve avulsion is often obscured by the presence of concomitant vitreous haemorrhage. Electrodiagnostic tests, CT scan and fluorescein angiography have not proved helpful in substantiating the diagnosis of this entity in the early stages. We herein present the echographic features in a case of post traumatic optic nerve avulsion that, to the best of our knowledge, have not been previously described. The role of ultrasonography in the diagnosis of suspected optic nerve head avulsion has been high-lighted.

Adolescent

Cryopexy in pars planitis.

Cryotherapy has been reported to be of benefit in pars planitis. We studied 16 eyes with classic pars planitis unresponsive to corticosteroid therapy. Eight eyes continued with systemic and periocular steroid therapy, and in the remaining eight eyes transconjunctival cryopexy of the peripheral retina and vitreous base was done as an additional procedure. At 6 months four of the eyes that received cryopexy showed an improvement in Snellen visual acuity, and in the other four the acuity was unchanged; none of the eyes showed any vitreous base neovascularization. Among the eyes that received steroid therapy only, the acuity was unchanged in five, improved in one and reduced in two.

Adolescent

Contrast sensitivity changes in background diabetic retinopathy.

Previous reports of contrast sensitivity in diabetic patients have shown conflicting results. We evaluated contrast sensitivity using Cambridge low-contrast sensitivity charts in 22 diabetic patients (22 eyes without retinopathy and 16 eyes with background retinopathy on fluorescein angiography) and 10 control subjects (20 eyes) matched for age and sex. The mean contrast threshold values at a spatial frequency of 4 cycles/degree were 0.46%, 0.60% and 0.43% in the three groups of eyes respectively. Contrast sensitivity was significantly lower in the diabetic eyes with retinopathy than in the normal eyes (p = 0.011) or the diabetic eyes without retinopathy (p = 0.033). This test may be of value in screening diabetic patients for retinopathy in primary care facilities.

Contrast Sensitivity

Subretinal fluid in the diagnosis of posterior scleritis.

The etiology of subretinal mass lesions is very difficult to establish. A 28-year-old man presented to us with an area of choroiditis, which progressed, despite corticosteroid and antibiotic therapy, to an exudative retinal detachment, secondary glaucoma and a painful blind eye. To develop a means of identifying the cause of such lesions, we did a subretinal fluid tap prior to enucleation. Cytopathology showed only inflammatory cells and the final histopathological diagnosis was that of a granulomatous scleritis.

Adult

Communicating intravitreal cysticercosis.

A viable intravitreal cysticercus cellulosae communicating with subretinal space was identified in a 45-year-old man. The cyst was removed in toto via the direct scleral approach without incident. To our knowledge this is the first report of intravitreal cysticercus with subretinal extension removed successfully by the direct route. The role of careful ultrasonic scanning in cases of intravitreal cysticercosis is emphasized.

Betamethasone

Retinal toxicity of trace elements.

Acute toxicity of lead, nickel and cobalt on rabbit retina was studied. It was found that all these metals produced similar photoreceptor degenerative changes, but lead produced extensive degenerative changes at ganglion cell layer also. Electroretinographically nickel group showed statistically (by analysis of variance) significant prolongation of 'b' wave implicit time as seen in autosomal dominant retinitis pigmentosa.

Animals