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Biomedical subjects

H Karoń

Publications and source records attributed to H Karoń.

At least 19 recordsLinked to original sources
PubMed1992

The effect of an experimental neoplastic disease on the flux of sodium and potassium ions across red blood cells and on the lipid composition of their membranes.

The erythrocytes from Morris Hepatoma 5123 bearing rats took up Na+ and K+ ions from the incubation medium and released Na+ into the extracellular space at lower rates than did erythrocytes from intact control rats. The lipid composition of erythrocytes membranes from the tumor-bearing rats differed from that of membranes from unaffected rats, showing increased contents of phospholipid phosphorus and a decreased content of cholesterol, resulting in decreased cholesterol:phospholipid molar ratios.

Animals↗
PubMed1989

Polymorphonuclear neutrophils function in splenectomized patients.

Some essential functions of polymorphonuclear neutrophils (PMN) were evaluated in 30 patients splenectomized because of rupture of the spleen. These cells revealed normal random migration, adherence, unstimulated O2- and H2O2 production. Phagocytosis of viable staphylococci was higher than in controls, whereas chemotaxis, bactericidal capacity, aggregation and stimulated O2- and H2O2 production were significantly impaired. PMN from splenectomized patients manifested also the decreased intracellular myeloperoxidase activity. The percentage of cells with receptor for Fc IgG in peripheral blood was markedly decreased. Plasma of these patients induced increased adherence of autologous as well as control neutrophils. The possible mechanisms leading to the observed events are discussed.

Adolescent↗
PubMed1978

[Changes in the activity of glucose-6-phosphate dehydrogenase and in the content of reduced glutathione in red blood corpuscles in the case of tumorous diseases in the maxillofacial region (author's transl)].

The activity of glucose-6-phosphate dehydrogenase and the glutathione content of red blood corpuscles were determined in twenty-five patients with tumors (of which nineteen were malignant and six, nonmalignant) as well as in a control group of twelve normal subjects. The activity of glucose-6-phosphate dehydrogenase was markedly higher in all of the tumor patients than it was in the controls. Also, the activity of glucose-6-phosphate dehydrogenase was found to increase with the time of existence of an untreated tumor.--Increased glutathione contents were determined especially in the early stages of tumor development. In patients with a relatively long record of malignant and nonmalignant tumorous diseases as well as in normal subjects there was observed no or only an inconsiderable increase in the content of glutathione.--This method of examination is assuming considerable importance for the differential diagnosis of tumors located in the maxillofacial region.

Erythrocytes↗