Antismoking education for medical students.
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Biomedical subjects
Publications and source records attributed to H Kawane.
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A survey of the smoking habits and attitudes toward smoking among all members of the Japan Society of Chest Diseases has been carried out. Of the 6,224 members of the Society who were sent a voluntary questionnaire, 3,640 (58.5%) responded. Of the 3,640 respondents, 24.8% were smokers, 39.4%, ex-smokers and 35.9%, non-smokers. The prevalence of smoking was lower than among physicians in general in Japan, which is estimated to be 39%, and much lower than the rate for the general male population (61.1%). For ex-smokers, the long-term health risks were the most important reason for giving up smoking, followed by the desire to set an example as medical personnel. The great majority of respondents (91.7-97.3%, depending on smoking status) believed that smoking should be restricted in certain places. Hospitals and clinics had the highest percentage for places where smoking should be restricted. About two-thirds of the respondents also believed smoking should be restricted at medical meetings.
A 63-year-old woman was referred to our division because of massive hemoptysis (200 ml) after administration of ticlopidine, an anti-thrombotic drug, for prevention of recurrent brain infarction. Ticlopidine treatment was stopped on the first hospital day, thereafter the patient's hemoptysis immediately disappeared. A chest roentgenogram and broncho-fiberscopic examination did not reveal any organic lesion associated with hemoptysis. Laboratory data revealed prolonged bleeding time and decreased platelet aggregation, suggesting that the patient had had a hemorrhagic diathesis associated with the administration of ticlopidine. Although many anti-thrombotic drugs have been recently employed in a variety of clinical cases, the patient's hemoptysis was considered to be due to side effects.
A 52-year-old man receiving maintenance hemodialysis for 6 years was referred to our division for further evaluation and additional therapy for cough and hemosputum lasting 2 months, and for examination of a chest roentgenographic abnormality. Transbronchial lung biopsy specimens revealed squamous cell carcinoma of the lung. A total of 8 courses of anticancer chemotherapy with 25-30 mg/m2 of CDDP performed biweekly resulted in a partial remission (56%) but no side effects, including gastrointestinal damage and agranulocytosis. Few cases of lung cancer receiving anticancer chemotherapy with CDDP during maintenance hemodialysis have been reported. Administration methods and dosage of CDDP for patients receiving maintenance hemodialysis were discussed.
Changes in leukocytes and eosinophils in 60 patients with non-infectious attack (NIA patients) were compared with those in 50 patients with infection-related attack (IRA patients). In 30 (50%) of the 60 NIA patients, eosinophilia without leukocytosis was observed on admission, and in 23 (76%) of these 30 patients eosinophilia disappeared within 2 weeks of admission. In 36 (72%) of the 50 IRA patients, leukocytosis without eosinophilia was observed on admission, and the periods from the onset of infection to admission were inversely correlated with leukocyte counts. In 22 eosinophilia patients among the 50 IRA patients, the periods from the onset of infection to admission were correlated with eosinophil counts for up to 40 days, and in 13 (76%) of 17 eosinophilia patients not receiving a long-term steroid therapy during admission, eosinophilia continued for more than 2 weeks even after anti-asthmatic and anti-infectious therapies. There was no significant difference in serum IgE levels between the two groups on admission. These results suggest that evaluations of leukocytes/eosinophils on admission and clinical courses are very useful in the management of asthmatic patients with or without bacterial infections.
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We described 6 points of the present situation and the future prospect of pulmonary function tests. The pulmonary function test using different equipment on the same subject gave different results. The results of the pulmonary function test were affected by the subject's efforts. There were no standard prediction equations. Normal subjects and patients with respiratory disease reached the limit of exercise tolerance when the ratio of tidal volume during exercise to vital capacity (VT/VC ratio) approached 50%. Respiratory rehabilitation was evaluated by pulmonary function tests. The development of equipment allowing measurement by subject's quiet breathing is awaited.