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Biomedical subjects

H Kayano

Publications and source records attributed to H Kayano.

29 records · Page 2Linked to original sources

Primary hepatic lymphoma presenting as intravascular lymphomatosis.

A case of primary hepatic lymphoma presenting as intravascular lymphomatosis was diagnosed in a 69-year-old woman who presented with symptoms related to the digestive tract. These symptoms were followed by neurologic disorders, including disturbance of sensation and mentality, and pathologic reflexes suggestive of a broad intracerebral lesion. Computed tomography of the brain showed an ill-defined, low-density area in the bilateral parietotemporal lobes. Autopsy revealed a well-circumscribed hepatic tumor, 6 cm in diameter, and scattered hemorrhagic foci in the cerebral cortexes. Microscopically, the hepatic tumor was a diffuse lymphoma, large cell, of the B-cell type. The small vessels of the brain were found to be packed with lymphoma cells, having caused the florid neurologic manifestations.

Aged↗

Melanotic schwannoma arising in the sympathetic ganglion.

A case of melanotic schwannoma, the 28th reported in the literature and the second to arise in the sympathetic ganglion, was reported in a 39-year-old man who remains free of recurrence or metastasis since removal of the tumor. In common with earlier benign melanotic schwannomas, its ultrastructural study revealed well-developed contiguous external lamina as opposed to absent or only minimally developed external lamina seen in malignant melanotic schwannomas. This emphasizes the use of electron microscopy in the diagnosis of this tumor. The literature yields only nine melanotic tumors (including one malignant melanotic schwannoma) arising in the sympathetic nervous system; all nine tumors had a malignant clinical course. Therefore, the present case represents the first "benign" tumor among ten melanotic tumors, and the second among 28 melanotic schwannomas to arise in the sympathetic nervous system.

Adult↗

Cross-reacting antibodies to human T cell leukemia virus-I and -II in Japanese patients with hairy cell leukemia.

Sera from 11 Japanese patients with hairy cell leukemia and 4B122, an anti-hairy cell serum produced by the authors, were surveyed by Western blot analyses for cross-reacting antibodies to human T cell leukemia virus (HTLV)-I and -II virions released, respectively, from Lma-66 and Mo-T cell lines. Sera from the majority of the patients showed positive reactions with p15, p19, and/or p24 of HTLV-I and with p21 and/or p22 or HTLV-II. 4B122 was weakly cross-reactive with HTLV-II but not with HTLV-I. These results militate against the involvement of HTLV-I or -II but may implicate a role by a cross-reacting, previously unrecognized retrovirus in the pathogenesis of hairy cell leukemia in Japanese patients.

Antibodies, Viral↗

A case of hypervascular renal capsule leiomyoma.

A case of leiomyoma of the kidney is reported. A 54-year-old woman was found incidentally to have a solid left renal mass on abdominal ultrasound examination performed during a follow-up study for chronic hepatitis, type C. Computed tomography (CT), dynamic magnetic resonance imaging (MRI), and angiography revealed the hypervascular mass. Partial nephrectomy was performed under a preoperative diagnosis of renal cell carcinoma. Histopathology diagnosed the mass as renal capsular leiomyoma. We considered that the hypervascularity of the tumor was related to the presence of rich capillary beds.

Angiography↗