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H Kersting

Publications and source records attributed to H Kersting.

13 recordsLinked to original sources

Simulation system SONCHES-based toxicokinetic model and data bank as a tool in biological monitoring and risk assessment.

This paper describes the use of an interactive simulation system (SONCHES) as a model and databank system. The basic model is a physiologically based toxicokinetic model (partition coefficient concept). This model takes circulation times into consideration and includes a metabolic subsystem with spot urine output. Data libraries related to the physiology of mammals, chemical substances, the external environment (exposure, physical activity, skin uptake, water intake) and real experiments allow various simulation experiments (scenarios). Scenario service and result post processing can be used to compare real experiment and simulated data (data-gathering and interpretation).

Computer Simulation↗

[Color Doppler echocardiography in emergency diagnosis of ventricular septal rupture after acute myocardial infarct].

A 58-year-old man developed a rupture of the interventricular septum after acute posterior myocardial infarction. The two-dimensional echocardiographic features of the ruptured interventricular septum included akinesia of posterior wall, hyperkinesia of the interventricular septum and anterior wall, inferior basal septum aneurysm and visualization of the ventricular septum defect. Injection of echocardiographic contrast (Gelatin solution) into the right atrium showed a small right-to-left shunt, injection into the left ventricle (during heart catheterization) demonstrated massive crossing of echocontrast similar to the results of cineventriculography of the left ventricle. By coloured Doppler-echocardiography the left-to-right shunt could directly be visualized, as well as a diastolic right-to-left shunt. By calculation of pressure gradient using adjusted continuous wave Doppler, estimation of right ventricular pressure was possible. The results demonstrated that colour Doppler in addition to two-dimensional echocardiography has an important diagnostic role in patients with complications of myocardial infarction.

Echocardiography↗

[Ultrasound-guided percutaneous one-step nephrostomy].

The percutaneous nephrostomy-set described is a two-piece desposable set for temporary or permanent urine drainage. Under combined sonographic and radiologic control the thin but stabilised puncture needle, used alone, offers the advantage of permitting definitive establishment of the fistula in a fast and safe manner without changing of the guide instrument and without any troublesome bouginage.

Humans↗

[Transient neurogenic bladder-emptying disorder caused by herpes genitalis following kidney transplantation].

We report on a case of transient neurogenic dysfunction of the urinary bladder caused by herpes genitalis in a renal transplant patient. The patient noticed a slow urinary stream 3 days after the vesicular stage of the herpes genitalis. After 9 days complete urinary retention and loss of sensation developed, necessitating the insertion of suprapubic tube. Symptoms and residual urine spontaneously disappeared after 20 days. After removal of the suprapubic tube the patient could empty his bladder completely with good stream. 45 cases of this kind have been described in the literature. the cause is a sacral meningo-radiculitis with herpes simplex virus leading to a transient neuromotoric paralysis of the bladder.

Adult↗