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Biomedical subjects

H Kiguchi

Publications and source records attributed to H Kiguchi.

25 records · Page 2Linked to original sources
PubMed1989

Weber-Christian disease associated with multiple perforations of the ileum and colon.

Panperitonitis developed in a 57-yr-old Japanese man during the course of Weber-Christian disease (WCD). Emergent operation disclosed three perforations of the ascending colon and two of the distal ileum. Histological study of the surgical specimen showed that all perforations were located at the centers of acute subserosal panniculitic foci. No vasculitis was discerned. In the previously reported three cases of WCD with intestinal perforation, perforation was solitary and seen in the small intestine. The cause of perforation was considered to be vasculitis in two cases. In the remaining one, panniculitis around the perforation was in chronic granulomatous stage. This was the first case of WCD in which acute subserosal panniculitis caused multiple ileocolonic perforations.

Acute Disease↗
PubMed1986

Myocarditis with myocardial infarction like findings in a 3-year old girl.

A 3 year-old Japanese girl had an acute onset associated with vomiting. The electrocardiogram (ECG) indicated changes similar to those of acute myocardial infarction (MI); there was no past history of kawasaki disease. Selective coronary angiography taken on the 28th day of illness revealed no abnormality. Thallium 201 scintigraphy was also performed and it revealed that the area of absent myocardial uptake was in the anterior wall. In serological findings, antibody titers against Coxsackie B-3 virus had risen significantly; therefore acute myocarditis caused by Coxsackie B-3 virus infection was diagnosed.

Antibodies, Viral↗
PubMedDate not supplied

Follicular bronchiolitis (FBB) associated with Legionella pneumophilia infection.

An 8-month-old girl with respiratory distress and stridor was admitted to the authors' hospital. Two days later, she died of respiratory insufficiency due to pneumonia. Autopsy confirmed the presence of follicular bronchiolitis (FBB) in both lungs. After considering her clinical course, the authors focused on three pathogens: Legionella pneumophilia, Pneumocystis carinii, and Mycobacterium tuberculosis. Only Legionella pneumophilia was detected by both immunohistochemistry and PCR.

Bronchiolitis↗
PubMedDate not supplied

Follicular bronchiolitis associated with Legionella pneumophilia infection.

An 8-month-old girl with respiratory distress and stridor was admitted to our hospital. Two days later, she died of respiratory insufficiency due to pneumonia. Autopsy confirmed the presence of follicular bronchiolitis (FBB) in both lungs. After consideration of her clinical course, we focused on three pathogens: Legionella pneumophilia, Pneumocystis carinii, and Mycobacterium tuberculosis. Only Legionella pneumophilia was detected by both immunohistochemistry and polymerase chain reaction.

Bronchiolitis↗
PubMedDate not supplied

Multiple penetrating colonic ulcers in secondary amyloidosis caused by rheumatoid arthritis.

An autopsy case of multiple penetrated colonic ulcers with secondary amyloidosis caused by rheumatoid arthritis in a 61 year old woman is reported. Amyloid deposition was conspicuous in the transverse colon with numerous penetrating ulcers that were circumferentially scattered. Deposition was mainly in the small vessel walls of the submucosal layers. In the quantitative comparison of the histological components between the colonic segments affected by severe and mild ulcer formation, occlusive vascular amyloid deposition was revealed more frequently in the severe involved portion than in the mild involved portion. In addition, submucosal fibrosis that tended to appear around ulcers was more extensive and thicker in the former than in the latter. The complete vascular occlusion caused by amyloid deposition was particularly concentrated in the submucosal layer adjacent to the ulcer. These findings indicate that peripheral circulatory disturbance by amyloid deposition in the small vascular walls leads to ulcer formation in the colon.

Amyloid↗