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Biomedical subjects

H Klausen

Publications and source records attributed to H Klausen.

17 recordsLinked to original sources
PubMed1990

[Resuscitation].

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Humans↗
PubMed1989

[Organic brain damage in garage workers after long-term exposure to diesel exhaust fumes].

Diesel motors are employed to an increasing extent for occupational transport and fumes from diesel driven vehicles constitute an increasing problem as regards atmospheric pollution but, in particular, they constitute a considerable risk to health for the workers exposed to diesel exhaust fumes in their daily work. In the clinic for occupational medicine, The University Hospital, Copenhagen, 14 garage workers were examined. Eleven of these had been exposed to great quantities of diesel exhaust fumes for 2 to 29 years. All 11 presented acute symptoms due to diesel exhaust fumes in the form of headache, vertigo, fatigue, irritation of mucous membranes, nausea, abdominal discomfort or diarrhoea. Seven persons had been employed for more than five years as garage workers. Six complained of failure of memory, difficulty in concentration, irritability, increased sleep requirement, psychological changes or reduced libido. Neuropsychological examination was undertaken in these six persons and in five of them organic brain damage, mainly of slight extent, was demonstrated. Diesel exhaust fumes contain many toxic substances: carbon monoxide, nitrous gases, sulphur oxides, aldehydes and hydrocarbons. It is not possible to indicate a single compound which is responsible for possible brain damage and a combination effect may well be concerned. This is a casuistic material. Only few investigations have previously been available which illustrated a possible connection between the neurotoxic effects and, in particular, brain damage. It is now considered important to emphasize that this may constitute a problem on exposure to diesel exhaust fumes.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1987

Chronic toxic encephalopathy in solvent-exposed painters in Denmark 1976-1980: clinical cases and social consequences after a 5-year follow-up.

On the basis of previous investigations from occupational medicine, neurology, and neuropyschology, a retrospective evaluation was made of 21 painters in whom chronic toxic encephalopathy following exposure to organic solvents had been diagnosed during a stay in the Neurology Department of Gentofte Hospital, Copenhagen, in the period 1976-1980. All the painters had given up their jobs for this reason. The assumption of a causal relationship between the exposure and the intellectual impairment was supported by a possible dose-effect relationship. The chronic toxic symptoms had considerable social consequences. Five years later, ten had not gotten other jobs. The lack of working ability was correlated to advancing age, increasing exposure, and increasing intellectual impairment. According to the results of the study, conditions at work places ought to be changed in such a way that harmful exposure can be prevented in the future.

Adult↗