Biomedical subjects
Publications and source records attributed to H Klemm-Mayer.
We report on two patients suffering from circumscribed scleroderma as well as lichen sclerosus et atrophicus. The cases are remarkable because it was possible to demonstrate histopathologic markers of both conditions in the same specimen.
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We report a 60-year-old patient suffering from malignant melanoma and multiple cutaneous, lung, and intraabdominal metastases. After 6 series of combination chemotherapy ( BNCU , Hydroxyurea, Dacarbacin ), the metastases showed a remarkable regression. At present, the patient is in a nearly complete remission.
High molecular pathogenic substances are eliminated from the blood by plasma exchange. Main indications are autoimmune disorders; the experiences with this therapy in dermatological disorders are reviewed. In psoriasis vulgaris immunoglobulins and antigen-antibody-complexes has been discussed as pathogenetic, too; we have therefore treated four patients with psoriasis by plasma exchange. Although we observed a surprising clinical improvement during the initial phase of therapy, the final results are not convincing.
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