PubMed Health⌕ Search

Biomedical subjects

H Koch

Publications and source records attributed to H Koch.

At least 37 records · Page 2Linked to original sources
PubMed1978

Endoscopy of the biliary tract and the pancreas in children.

ERCP is a useful method in adults for diagnosing bilio-pancreatic disorders. The application of this technique in children is limited until now according to the rare case reports in the literature. Our experience with this procedure, based on the examination of six children and 12 youths, shows that ERCP can be employed with great benefit, when taking into account the correct indication. ERCP is mainly applied to clarify obstructive jaundice, especially when anomalies of the bile duct system are suspected, and to discover a reason for relapsing pancreatitis where other procedures fail. Blunt abdominal traumata with upper GI bleeding may well be another reason. In general our first reported data are encouraging.

Adolescent↗
PubMed1978

Peroral cholangioscopy in choledocho-duodenostomy--patients using the pediatric fiberscope.

In patients with wide-open bilio-digestive anastomoses peroral cholangioscopy using the pediatric endoscope GIF-P2 is easily performed. The common bile duct is visualised down to the papilla and up to the distributaries of the hepatic ducts. The instrumentation channel allows mobilisation of incarcerated concretions, extraction of food particles (cholangiophytiasis) and guided biopsy of pathological findings. The experience in 12 patients with this method is promising.

Bile Ducts↗
PubMed1978

Ultrastructural changes of colonic mucosa in patients with chronic laxative misuse.

Laxatives are amongst the most widely used and misused drugs. Especially the "irritant chathartics" are associated with severe cell poisoning. Electrolyte disturbances like potassium deficiency may occur as a result of enhanced potassium secretion into the colon. Ultrastructural studies of patients with chronic laxative misuse demonstrate, that this functional disorder is correlated with damage of the colonic epithelial cells consisting in stereotyped lesions as changes in microvilli, reduction and structural defects of cytoplasmic organelles and an increase of lysosomes and dense bodies. The lesions have a focal distribution and may explain the potassium loss from a morphological point of view.

Cathartics↗
PubMed1977

[Limitations in the internistic treatment of ulcerative colitis and Crohn's disease].

Aetiology of ulcerative colitis and Crohn's disease is unknown. Therefore causal therapy is not possible. Conservative treatment for both diseases is of antiinflammatory, symptomatic and substituting nature. Surgical intervention is indicated if conservative treatment fails or if dangerous complications occur. The right moment for an operation can only be determined in close cooperation between internist and surgeon.

Adrenocorticotropic Hormone↗
PubMed1977

[Peptone-stimulated gastric secretion and antacids. Effect of antacids with various content of calcium, magnesium and aluminiumions on the peptone-induced secretion of gastric juice, double-blind study].

A double-blind-trial was performed to prove the effect of antacids containing Mg (OH)2, Al (OH)3 and CaCO3 on peptone-stimulated gastric secretion (intragastric titration). A high efficacy of antacids given after meals was demonstrated. After application of antacids no significant rise in serum gastrin levels during intragastric titration was found. Serum calcium and magnesium levels remained unchanged. Peptone-stimulated gastric secretion was not influenced by application of different antacids within a period of 2 hours.

Aluminum↗
PubMed1977

Cancer and the environment.

The environment is becoming an increasingly important factor in the aetiology of cancer. In addition to physical carcinogenic substances, chemical agents, in particular, are identified in ever increasing numbers as being oncongenic. This has been experimentally shown in the case of more than 1000 substances, of which 30 are also regarded as carcinogenic in humans. To be effective, aetiological research should lead to the elimination of the substances which are identified as harmful. In the present state of our knowledge, this will be a considerable contribution to prophylaxis.

Carcinogens, Environmental↗