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Biomedical subjects

H Konczaty

Publications and source records attributed to H Konczaty.

7 recordsLinked to original sources
PubMed1990

[Rheumatism and acne conglobata . Apropos of a new case, in a 13-year-old boy].

With reference to a new case of acne conglobata-associated rheumatic disease in a thirteen-year-old boy, we recall the characteristics of the main joint and/or bone manifestations that may occur during severe flares of acne conglobata, but also acne fulminans or pustulosis of the palms and soles. Joint manifestations mainly involve the large proximal joints of the limbs and consist in pain rather than in signs of inflammation. Although recurrences may develop, joint disease responds to treatment of the acne combined with a non-steroidal antiinflammatory drug. Bone involvement consists in true rheumatic osteitis with hyperostosis responsible for densification and thickening of bone, mainly in the anterior chest wall and spine. The pathogenesis and nosologic place of these bone and joint manifestations remain controversial: they do not seem to represent true reactive arthritis and, although the B27 antigen is usually lacking, they have been likened to the group of spondylarthropathies, especially in those cases with sacroiliac involvement and enthesopathy . Oddly enough, they are reminiscent of some of the side effects of etretinate, an agent prescribed in these severe forms of acne. After a national survey carried out in 1986, the acronym SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) was suggested to designate the range of skin, bone and joint manifestations observed.

Acne Vulgaris↗
PubMed1989

[Neisseria meningitidis: serogroup Y. Apropos of 38 cases].

Thirty-eight cases of infections due to Neisseria meningitidis serogroup Y have been studied. They correspond to the strains sent to the Laboratory (Centre National de Référence since 1987). Their repartition was: meningitidis 9 cases, purpura fulminans (6), septicaemia (5), respiratory syndroms (11), asymptomatic carriage (4), various (3). Patients were 4 months to 86 years old. Mortality was 13.2%. One third or meningitis or meningococcemia happened in correlation with complement deficiency or splenectomy. In most of cases bacterial diagnosis was made by general laboratories but only in two cases over 38 the serogrouping Y was made.

Adolescent↗