[Mikulicz's syndrome in 2 patients with acute leukemia].
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Acute Disease↗
Biomedical subjects
H Kordecki
Publications and source records attributed to H Kordecki.
[Myeloblastoma of the brain and spinal cord in a patient with acute myelomonocytic leukemia].
A case of the myeloblastoma involving brain and spinal cord in a patient with acute myelomonocytic leukemia is reported. Numerous mitoses within the tumor provide an evidence for local cell proliferation in the neoplasm. Surgery combined with radiotherapy is suggested as the most efficient modality of the treatment.
Adult↗
[The mechanism of cell proliferation in acute (immature-cell) leukemia].
In 40 patients with acute leukaemias the 3H-thymidine and mitosis indices were determined in the population of blast cells in bone marrow and the cellularity of bone marrow was determined. The studies were carried out in the first episode of the disease before treatment and in some patients (13) they were repeated during relapse after remission or improvement. The results showed that proliferative activity of blast cells was reduced in relation to precursors of normal granulopoiesis in all forms of acute leukaemia. Myeloblastic leukaemias showed a greater scater of values of both proliferation parameters in relation to lymphoblastic leukaemias. It was found, moreover, that in highly cellular bone marrow the proliferative activity of blast cell population was significantly lower than in patients with low bone marrow cellularity. On the ground of this observation the authors put forward the view that in acute leukaemias the intrinsic mechanism controlling the proliferation of cells is disturbed.
Acute Disease↗
[Results of the treatment of infectious complications in patients with non-Hodgkin's malignant lymphomas].
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Adolescent↗
The parameters of cellular proliferation in acute (immature-cell) leukemias.
In 20 patients with acute leukemia the 3H-thymidine labelling index and the mitotic index were determined in the population of leukemic blast cells and the degree of bone marrow infiltration was evaluated. Determinations were carried out in acute stage of the disease and in 4 cases additionally during improvement or remission and then during subsequent exacerbations. In the acute phase of the disease both indices were low in comparison with the indices obtained in normal granulocytopoiesis. In acute leukemia in 15 cases the bone marrow contained high or moderate number of cells, while in 5 remaining cases it was low. The 3H-thymidine labelling index and the mitotic index were lower in acute period of the disease in patients with bone marrow infiltration as compared with patients with hypoplastic bone marrow. During improvement both proliferation indices increased.
Acute Disease↗