Prognosis of chronic subdural hematoma using noninvasive skull impedance plethysmography.
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Biomedical subjects
Publications and source records attributed to H Kushi.
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We report a case of five aneurysms, including three giant aneurysms, a pair of symmetric aneurysms, and two fusiform aneurysms. The initial clinical symptom was a cerebral ischemic attack. On admission, the patient complained of sudden onset of speech disturbance. Physical examination showed left hemiparesis. Radiological studies, including computed tomography and cerebral arteriography, revealed multiple low density areas bilaterally in the basal ganglia and three fusiform giant aneurysms bilaterally in the middle cerebral arteries and basilar artery. Considering the difficulty of surgical treatment, the patient was discharged. Six months later, complaining of right hemiparesis and total dysphasia, the patient was readmitted to our department. CT scan on admission revealed no changes except for ischemic changes. During the second admission, another attack of subarachnoidal hemorrhage due to rupture of the left middle cerebral artery aneurysm occurred, and the patient died. Autopsy was performed, and two more aneurysms, not visualized in the former studies, were found in the right anterior communicating artery and the cortical branch of the right middle cerebral artery. The occurrence of aneurysms in such a fashion as seen in the present case is to be very rare in the aspect of the size, the multiplicity and the bilaterally development.
Using skull impedance plethysmography, a developmental approach was made to the measurement of mean cerebral blood flow (mCBF) from brain volume exchanging ratio (delta V) involved in bilateral jugular venous occlusion. An experimental study thereof revealed the following results: Comparative examinations were made between total cerebral blood flow obtained by the superior sagittal sinus hydrogen clearance method and delta V X t obtained by the present approach led to the establishment of a linear correlation there between and also of the following calculating formula: mCBF = k X delta V X t (omega X sec) k: proportional coefficient t: blood flow increasing time (10 sec.) The experimental results revealed that the present approach was valid enough as an index of cerebral blood flow. Some future improvements therein seem to make also its clinical application possible. The theory and method of the present approach are described with an examination of several points raised thereby.