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Biomedical subjects

H L Eng

Publications and source records attributed to H L Eng.

At least 91 records · Page 5Linked to original sources
PubMed1996

Nasopharyngeal tuberculosis.

Tuberculosis of the nasopharynx is uncommon and may mimic malignant disease. In this study, 14 patients (17-61 years old; 12 women, 2 men) who were histologically diagnosed as having nasopharyngeal tuberculosis were described. None of them bad known previous history of tuberculosis. Half of our patients had isolated nasopharyngeal tuberculosis with no apparent pulmonary involvement. Eleven patients present with enlarged neck lymph nodes and 6 of the 14 had blood-tinged nasal discharge. A bulging mass, with or without ulceration was the most common nasopharyngeal lesion encountered in 11 patients. Clinically, it appeared to resemble cancer presenting as a nasopharyngeal mass lesion with concomitant enlarged neck lymph nodes. It is important to consider tuberculosis in the differential diagnosis of nasopharyngeal lesions and take biopsy specimens for histological and bacteriological studies.

Adolescent↗
PubMed1996

Malignant fibrous histiocytoma of the left ventricle: a case report.

Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adults, but is distinctly rare as a primary tumor of the heart. Herein we report a case of left ventricular MFH obstructing the outflow tract and presenting as congestive heart failure. Surgical removal of the mass confirmed the tissue diagnosis of MFH. To our knowledge, this is the first report of MFH originating from the left ventricle.

Aged↗
PubMed1995

Tuberculosis presenting as a solitary splenic tumour.

A 48-year-old male had suffered from body weight loss and general malaise for 2 months. Abdominal computed tomography showed a dilated intrahepatic duct with stones and a hypodense nodular mass in the spleen. A splenectomy and distal pancreatectomy were performed under the preoperative impression of a malignancy. Histological examination of the specimens revealed tuberculosis.

Diagnosis, Differential↗
PubMed1995

Dramatic response to levamisole and low-dose prednisolone in 23 patients with oral lichen planus: a 6-year prospective follow-up study.

The purpose of this prospective study was to evaluate the short-term and long-term clinical efficacy of levamisole used with low-dose prednisolone in patients with refractory oral lichen planus. Twenty-three patients with OLP who had been treated unsuccessfully with other modalities were given 150 mg/day levamisole and 15 mg/day prednisolone for 3 consecutive days each week. Twelve patients showed dramatic remission of signs and symptoms within 2 weeks, whereas 11 had partial remission. All 23 reported significant pain relief and showed no evidence of erosive oral lichen planus after 4 to 6 weeks of treatment. All 23 also remained free from symptoms for 6 to 9 months after the treatment ended. There were few side effects from this treatment besides minor skin rash, headache, and insomnia from the levamisole in three cases. We conclude that the addition of levamisole to prednisolone may produce improved results in the management of erosive oral lichen planus.

Administration, Oral↗
PubMed1995

Tumoral calcinosis after thumb tip injury: case report.

Tumoral calcinosis, developed in a 44-year-old male patient after a left thumb tip injury that was initially treated with a wraparound procedure, was excised. Five years after excision, there was no recurrence, and the thumb remained well-functioning.

Adult↗
PubMed1995

Use of laparoscopy in intersex patients.

PURPOSE: Management of impalpable gonads in intersex patients remains a challenging problem. Since laparoscopic gonadectomy or gonadal preservation has been used in the management of impalpable gonads in the normal male population, laparoscopy can be an alternative method in the treatment of intersex patients. MATERIALS AND METHODS: Laparoscopic operations were performed on 6 patients with intersex conditions, including the testicular feminization syndrome in 2, 17 beta-hydroxysteroid dehydrogenase deficiency in 1, 5 alpha-reductase deficiency in 1 and mixed gonadal dysgenesis in 2. RESULTS: Laparoscopic gonadal biopsy, gonadectomy and hysterosalpingectomy were done in select patients. CONCLUSIONS: Although the initial diagnoses were made by phenotypic presentation, and biochemical and cytogenetic studies, laparoscopy had an important role in defining the internal ductal and gonadal structures to confirm the diagnosis, and served as an efficient method for gonadectomy and removing structures contrary to the assigned gender.

3-Oxo-5-alpha-Steroid 4-Dehydrogenase↗
PubMed1995

Amniotic band syndrome: report of two autopsy cases.

The amniotic band syndrome is a collection of congenital deformities presumably due to rupture of amniotic sac. It appears to cause fetal injury through three basic mechanisms including malformation, disruption, and deformation. The associated anomalies vary from minor digital defect to major craniofacial and visceral defects. They can be categorized as neural tube-like defects, craniofacial anomalies, limb anomalies, abdominal and thoracic wall defects, visceral anomalies, and constriction bands. We present two autopsy cases and discuss the diagnostic features. Our findings support Torpin's theory that the fibrous constriction bands generated from early rupture of the amnion. An accurate diagnosis may be achieved by looking for the major features of amniotic band syndrome and a routine chromosome study and placental examination in cases with multiple congenital deformities.

Abnormalities, Multiple↗
PubMed1994

Sebaceous carcinoma arising in a benign dermoid cyst of the ovary.

Sebaceous carcinoma in a ovarian dermoid cyst is a rare entity. The present patient has survived 54 months and has no evidence of recurrence after total abdominal hysterectomy, bilateral salpingo-oophorectomy and adjuvant chemotherapy with cisplatin, vinblastine, and bleomycin.

Adenocarcinoma, Sebaceous↗
PubMed1994

Gastric leiomyosarcoma: a clinicopathological review.

OBJECTIVE: To report our experience of eight patients with primary gastric leiomyosarcoma. DESIGN: Retrospective study. SETTING: Teaching hospital, Taiwan. SUBJECTS: 8 patients who presented with primary gastric leiomyosarcoma between 1986 and 1990. MAIN OUTCOME MEASURES: Endoscopic, radiological, and histopathological features, DNA ploidy, and outcome. RESULTS: Abdominal pain and gastrointestinal bleeding were the most common presenting symptoms. In 5 of the 7 patients who had endoscopy preoperatively a diagnosis of submucosal tumour was made, but a definite diagnosis of leiomyosarcoma was made in only 3. A provisional diagnosis of leiomyosarcoma was made in 3 of the 4 patients who had computed tomography. All patients underwent some form of gastric resection ranging from palliative resection to total gastrectomy. Patients in whom the tumour had invaded adjacent organs had a poor prognosis. Histopathological grading of tumours correlated well with DNA ploidy. CONCLUSION: Both histopathological grading and DNA ploidy could be helpful objective prognostic criteria in patients with primary gastric leiomyosarcoma.

Aged↗
PubMed1994

Twin pregnancy with hydatidiform mole (46, XX) and a coexistent fetus (46, XY): report of a case.

Coexistent hydatidiform mole (46, XX) and live fetus (46, XY) in the second trimester is a rare phenomenon. In this case, the clinical manifestations presented as pregnancy-induced hypertension, including hypertension, proteinuria and oliguria. Ultrasonic examination found an enlarged placenta with a typical honeycomb picture, placenta previa and a normal developing fetus. The patient underwent an emergency cesarean section at 23 weeks' gestation on a preliminary diagnosis of acute chorioamnionitis. A 700 g immature male baby was delivered with Apgar scores of 3 at one minute, and 7 at five minutes. The placenta was composed of two parts: one was a molar pregnancy and the other was a normal placenta, both were separated by the membrane. The membrane consisted of one chorion and two amnions. Postmolar persistence of human chorionic gonadotropin was found one month after termination of this pregnancy. Chemotherapy with a single agent (methotrexate) was given. The patient is doing well and has no evidence of recurrence after one year of follow-up.

Adult↗