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Biomedical subjects

H L Lim

Publications and source records attributed to H L Lim.

22 records · Page 2Linked to original sources

Cancer: To tell or not to tell?

After a patient is diagnosed with a malignant illness, the physician is often left with the dilemma of how to communicate the diagnosis to the patient and the family. In the West, it is often the consensus that the patient be told. This is not necessarily true elsewhere, eg in Japan, the patient is often not told. A questionnaire survey was done to study how Singapore doctors feel about revealing the diagnosis of cancer to the patient. 90.4% of respondents will reveal the diagnosis to the family, while only 43.6% will inform the patient. The possible reasons are discussed.

Attitude of Health Personnel↗

The toxic strept syndrome: two case reports.

We describe two patients with group A beta hemolytic streptococcal septicemia from minor foci in the skin. They developed extreme toxemia, mental obtundation and multi-system organ failure associated with diffuse erythema. They both survived after appropriate antibiotic and intense supportive therapy. These are examples of the "toxic strept syndrome" which is similar to staphylococcal toxic shock.

Anti-Bacterial Agents↗

Fluprazine hydrochloride decreases copulation in male rats.

The copulatory performance of 18 sexually experienced male rats was tested 30 min after IP injection of the phenylpiperazine, Fluprazine Hydrochloride (4 and 8 mg/kg), or saline solution. Three 20-min tests with an estrous female were conducted at weekly intervals. Each drug dose produced a significant depressive effect on copulatory behavior (latency to and frequency of intromissions and ejaculations) without affecting social investigation. The increased latencies to mounting and intromission observed at both doses suggest that the primary action of the Fluprazine Hydrochloride is to interfere with the transition from social to copulatory patterns. Although the drug's mode of action is currently unknown, the present findings suggest that it operates on some common mediator of sexual and aggressive behavior.

Animals↗