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H L Ross

Publications and source records attributed to H L Ross.

25 records · Page 2Linked to original sources
PubMed1987

Britain's Christmas Crusade against drinking and driving.

Great Britain's 1983 "Christmas Crusade" against drunken drivers, during which the police of England and Wales administered an average of 1350 breath tests daily, is discussed. Although not deliberately planned and organized, the campaign, fueled by press reports, was perceived by many observes to be a national organized deterrent effort. To test the hypothesis that the crusade reduced drunken driving, the index of total automobile crash-related fatalities was used in the analysis. Results showed that the index declined significantly during the month of the crusade, providing support for the hypothesis of deterrent effect. The experience of the Christmas Crusade reinforces the expectation that deterrent interventions involving highly publicized campaigns increasing the certainty of punishment for illegal behavior can be successful over a limited period of time.

Accidents, Traffic↗
PubMed1986

The brewing industry views the drunk-driving problem.

A survey of executives in the largest U.S. and Canadian brewing companies reveals acknowledgment of a drunk-driving problem in which their product is implicated through misuse. It is thought that the industry can and should endorse countermeasures premised on the responsibility of the driver and drinker, which leads to active cooperation with the anti-drunk-driving movement in North America. However, the industry can and should oppose drunk-driving countermeasures premised on a negative view of the product; this stance is likely to result in future conflict with the movement.

Accidents, Traffic↗
PubMedDate not supplied

Reaction with DNA and mutagenic specificity of syn-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide.

The spectroscopic characterization of purine deoxyribonucleoside adducts derived from the fjord-region syn-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide and the mutagenic specificity of the latter compound for the supF gene in the pSP189 shuttle vector are described. This dihydrodiol epoxide preferentially forms adducts with deoxyadenosine residues in DNA and is preferentially opened trans in reactions with DNA or with deoxyribonucleotides. In common with other fjord-region syn-dihydrodiol epoxides, the most frequently observed mutational changes were A-->T and G-->T changes. This hydrocarbon dihydrodiol epoxide is structurally similar to syn-benzo[c]phenanthrene 3,4-dihydrodiol 1,2-epoxide but has an additional benzene ring annelated distant from the reaction center. As anticipated, there were some common features in the chemistry and mutagenicities of these two compounds, but there were also substantive differences which indicate factors of importance in controlling reactions of these kinds of compounds with DNA.

Animals↗