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Biomedical subjects

H Löhr

Publications and source records attributed to H Löhr.

At least 55 records · Page 3Linked to original sources
PubMed1980

[Infection due to Yersinia enterocolitica in healthy and chronically ill children (author's transl)].

A septicaemic course of infection due to Yersinia enterocolitica developed in three children, two Italian girls with thalassemia (serotype 03) and a previously healthy boy (serotype 09). There were marked gastrointestinal symptoms. The boy required two transfusions for acute haemolysis. Because it may take a serious course, the possibility of this organism as the causative agent should be considered in the differential diagnosis of severe infections, especially in patients with chronic debilitating disease. The death rate is about 30%.

Blood Transfusion↗
PubMed1980

[Radiation-risk in catheterization and angiocardiography of the child (author's transl)].

The skin exposure and the energy transferred to the body (integraldose) increase with the child's growth. Nevertheless the mean body dose (integraldose/body-weight) is the highest in the youngest patient. The probability of roentgenray induced letal malignancy is approximately 1:9000--1:17000. The morbidity risk may be 2--3 times higher at the least.

Adolescent↗
PubMed1980

[Radiation exposure and radiation risks from body scanners (author's transl)].

The exposure received during investigation with the Delta 50 FS body scanner was measured in 150 patients. On the basis of data in IRCP 26, the somatic and genetic risk from the absorbed dose was calculated. The somatic risk per examination varies between 1:40 000 and 1:310 000, depending on the part of the body examined. The genetic risk (probability of radiation induced malformation in off-springs) is of the order of 1:19 000 to 1:1 5 million.

Abnormalities, Radiation-Induced↗
PubMed1980

[Radiation risk for the child in urinary tract roentgendiagnostic (author's transl)].

During one urogramm skin doses were measured between 0,1--0,9 Roentgen (R) in the radiation field. The testes dose was 6--41 mR. In mictioncysto-urethrography the skin dose was between 0,2 and 4,2 R/examination, and the testes dose 50--80 mR. The energy transferred to the body by the X-rays (integral dose) was 5,6--23 mJoule (mJ) per urogramm. The mean-body-dose (integral dose/bodyweight) was 1,3--0,6 mJ/kg per examination. The probability to induce a lethal disease (for example leukemia or malignoma) by this dose is approximately 1:50 000--1:500 000. The probability that exposure of the gonades induces mutations and thereby malformations in the following two generations is equally about 1:50 000--1:500 000.

Adolescent↗
PubMed1978

[Visceral kala-azar disease in a child (author's transl)].

Repeated blood cultures were negative in a six-year-old boy with high septic temperature. Rheumatoid arthritis, typhoid and brucellosis were excluded. There was no evidence of leukaemia (bone-marrow tests). There was hepatomegaly with increased transaminase activity. Cortisone treatment was begun for suspected collagen disease. Several liver needle biopsies at first revelaed increasingly severe necrotising changes, predominantly in the centres of the acini. There were no parasites demonstrable histologically. The spleen was increased in the isotope scan but, covered by the liver, not definitely palpable. Diagnosis of mediterranean Kala-Azar disease was then suspected (the parents reporting a camping holiday in Yugoslavia) and finally proven serologically. The previously treatment-resistant disease improved dramatically after administration of trivalent antimony (Fuadin).

Alanine Transaminase↗
PubMed1978

[Radiation dose and risk in gastrointestinal roentgendiagnostic of the child (author's transl)].

In gastrointestinal roentgendiagnostic of the child the exposure of the skin and the testis depends on body height and body weight. The dose grows with the age. The squaredose product (Rcm2) and the energy absorbed by the body (integraldose, rdkg) increases comparably. On the other hand the quotient integraldosis/body weight is similar for the different age-groups. The radiation risk (the probability to die as consequence of a roentgenray induced disease) is approximately 1:100,000 to 1:10,000,000.

Age Factors↗
PubMed1977

[Differences of X-ray exposure between roentgen examen with a conventional roentgen-screen-system and with an image intensifer-television-unit (author's transl)].

During roentgen examens of patients in the II. Medizinische Poliklinik the X-ray exposure was determined. It corresponded to the datas described in literature. Two groupes were compared: 518 patients examined with a conventional roentgen-screen-system and 642 patients examined with an image-intensifer-television-system. The results demonstrated that with exception of thoracical X-ray examination the replacing of the old system by the television system brought a remarkable increase of the X-ray exposure. The doses depended of the patients constitution to a high degree.

Adult↗
PubMed1977

[Radiation protection measurements at the intensive care unit and in the operating room].

For chest X-ray in the ward and for intraoperative cholangiography the registered doses were low. A limitation of the exposures or the operations was not necessary. For osteosynthesis operations the doses for the patient and the staff could be kept low by preparing the operation adequately, by using modern image-intensifer units with grid and automatic regulation in fluoroscopy, and with discipline in using fluoroscopy. During one week a surgeon could do eight osteosynthesis operations without reaching legally imposed dose limit. The control area could be restricted to a space around the patient with a radius of two meters.

Germany, West↗
PubMed1977

[Exposure doses of the patient and the medical staff during urological x-ray examens (author's transl)].

During 32 intravenous urografies and 48 angiografies of the kidney and the suprarenal glands the x-ray doses at the patient's skin and gonades were determined. During the angiografies the doses were measured at the hands, the gonades and the front (eyes) of the medical staff. The results are discusses. Because the x-ray doses are realtively high, the number of the pictures and the exposure time is to be reduced to the minimum. Clinical experience (sufficient training) and special knowledge is the best x-ray protection.

Adrenal Glands↗
PubMed1976

[Radiation exposure of patients and personnel in the endoscopic retrograde cholangiopancreaticography (author's transl)].

The results of the measurement of radiation protection in 54 patients and the involved personnel exposed to radiation (physician performing the endoscopy and the radiologist) during ERCP were analyzed. The radiation exposure values were relatively low and were within the range of those doses to be expected for gastroenterologic radiodiagnostics. After many years of experience, the radiation exposure for patients and physician can be further reduced. Actual danger from radiation need not be feared for the patient or the exposed personnel. The range of maximum values for radiation exposure set-up in the regulations for x-rays is so broad that, with endoscopic centers need not be decreased. Rather it can still be considerably increased.

Cholangiography↗
PubMed1976

[Albumin kinetics in superior mesenteric artery shock in rats].

1. After 1-hour-tourniquet of the arteria mesenterical superior of the rat the result is a loss of intravasal fluid into the small intestine. After 2-hour-tourniquet the loss of fluid into the samll intestine can be higher than the volume of plasma circulating at the start of the experiment. During therapy with plasma substitute on base of gelatine (Haemaccel) the volume of content of the small intestine increases further. 2. After 1-hour-tourniquet the content of intravasal albumin is diminished by 26%, after 2-hour-tourniquet by 46%. Under therapy with a plasma substitute the loss of intravasal albumin increases further. 3. After 1-hour-tourniquet a transient accumulation of albumin was found in the wall of the samll intestine which was reduced after 2-hour-tourniquet. 4. The intravasal albumin is excreted in the small and the large intestine. After 1-hour-tourniquet 46% of excreted albumin was found in the small intestine after 2-hour-tourniquet 61%. It can be demonstrated, that under replacement with plasma substitute the result is mainly an "albumin dilution effect". The wall of the small intestine becomes permeable to high-molecular weight substances with an average molecular weight below 60.000. An effective therapy with the plasma substitute of the AMS-shock should, therefore, contain carrier substances with a molecular weight higher than 60.000.

Animals↗
PubMed1975

[Determination of intravasal volume loss in arteria mesenterica superior shock in the rat and attempt for adequate substitution therapy].

In ams-shock of rats the weight of the small bowel contents of an animal 310 g of weight increases from 2.5 g to 13.0 g. The fluid loss into the bowel lumen amounts to 10.5 g and exceeds the plasma volume of 9.6 g. Drainage into the large bowel is not taken into consideration. After treatment of the ams-shock with gelatine infusion the weight of the small bowel wall increases significantly for a limited period of time to 3.2 g% body weight compared to normal controls with 2.3 g% body weight. After at least 24 hours the necrotic epithelium of the small bowel is fully recovered. Following ams-shock it is possible by means of gelatine infusion to improve the time and rate of survival significantly and to give support to the theory of volume loss.

Animals↗