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Biomedical subjects

H Löllgen

Publications and source records attributed to H Löllgen.

At least 91 records · Page 5Linked to original sources
PubMed1977

[Sports and breathing (author's transl)].

The effect of physical training on pulmonary function and the changes in pulmonary parameters during physical exertion is described. Respiratory mechanics, vital capacity, forced expiratory volume and related variables are of less importance in judging the state of physical fitness and training condition. On the other hand, ventilation, respiratory gas exchange and regulation of breathing are important. Continuous analysis of alveolar and arterial partial pressures of gas and measurement of diffusion capacity may improve the assessment of the exercise test and physical fitness. Regular physical training may be of increasing significance for the rehabilitation of patients with chronic lung diseases.

Humans↗
PubMed1976

[Therapy of chronic non-specific respiratory tract diseases. 2. Therapy of infection, oxygen therapy, supplementary therapy].

Based on the pathological findings and functional analysis treatment of chronic non-specific lung disease (CNSLD) consists in improvement of secretion disorders and airways obstruction as well as in antiphlogistic treatment. The agents and drugs for therapy of pulmonary impairment are reviewed, the efficacy, way of administration, and side effects are outlined. Drug therapy is complemented by digitalis, oxygen administration, physical measures, and causative therapy. With these complex therapeutic efforts an effective therapy of chronic non-specific lung diseases is possible.

Adrenocorticotropic Hormone↗
PubMed1976

[Sputum viscosity and pulmonary function measurements during a one-week parenteral treatment with a standardized oxidation product of oil of turpentine and terpin hydrate].

In 23 patients with chronic obstructive lung diseases, viscosity, airway resistance, arterial blood gases and acid-base balance, and sputum aspect were measured before and after one-week treatment with Ozothin, a substance from oxidation products of ol. terebinth. and terpinum hydratum. Within this time, viscosity of the sputum was reduced, airway resistance decreased, and arterial oxygen pressure slightly increased, whereas arterial carbon dioxide tension obvious change of sputum aspect could be observed. Correlation calculations revealed no significant relations between viscosity and the above cited lung function values. The results indicate that administration of Ozothin may liquefy viscous secretion and reduce sputum viscosity.

Adult↗
PubMed1976

Respiratory gas exchange and lung perfusion in man during and after head-out water immersion.

The respiratory gas exchange for O2, CO2, and CO has been studied in nine healthy male subjects before, during, and after head-out water immersion. Distribution of lung perfusion and ventilation were determined by quantitative double nuclide scintigraphy (131J and 99mTc) and by argon washout, respectively. The well-known decrease of PaO2 and increase of AaDO2 during immersion is accompanied by a decrease of the CO-transfer factor. Ventilation in relation to functional residual volume does not change significantly, whereas distribution of lung perfusion becomes more even, with an increase in the apical lung zones. Immediately after the end of immersion, PaO2 increases rapidly, exceeding the initial value under dry conditions. At the same time, lung perfusion is shifted markedly more towards the basal lung regions, exceeding the gravity-induced blood pooling in the erect subject under dry conditions. The observed changes tend to normalize within 2 min. The changes of respiratory gas exchange during and immediately after immersion can be explained by changes of the inequality of the ventilation-perfusion ratios.

Adult↗
PubMed1975

Measurement of partial pressure of gases in liquids by mass spectrometry.

The experimental setup of mass spectrometric determination of gas contents in liquids has been modified for continuous and discontinuous measurement of partial pressure of gases in liquids. The inlet system consists of a stainless steel capillary with slits covered by a silicone rubber membrane. Several gases can be measured simultaneously under static conditions and in flowing liquids. The measurement and calibration procedure is described. Results of the analysis of the test criteria, reproducibility, detection limit, response time, and depletion are presented. The difficulties in discontinuous measurement of oxygen in blood are explained by the complex permeation-diffusion process at the membrane and the form of the dissociation curve. With regard to solubility, physically dissolved gases can be determined without problems down to tensions of about 0.01 mm Hg. Continuous measurement of oxygen and carbon dioxide partial pressure in liquids, including blood, is possible with the described system.

Blood Gas Analysis↗
PubMed1975

Methodical aspects of perceived exertion rating and its relation to pedalling rate and rotating mass.

Methodical aspects of the relationship between pedalling rate and rotating mass and perceived exertion rating (PER; Borg, 1962) were studied in trained, untrained, and ill subjects in bicycle ergometry. Pedalling rate varied between 40 and 100 rpm, work load steps were 5, 10, 15 and 20 mkp/sec in the healthy subjects, and 2.5, 5, 7.5 and 10 mkp/sec in the patients. PER decreased with increasing pedalling rate in all healthy subjects. In the patients, PER increased moderately at work load of 2.5 mkp/sec, but decreased at higher work loads up to 80 rpm, followed by a slight increase at 100 rpm. Higher mass of the flywheel, studied in 6 trained subjects, lowered the PER insignificantly. In the healthy subjects, test criteria, such as reproducibility, reliability, sensitivity, and linearity remained almost unaffected by pedalling rate. In patients, increasing pedalling speed diminished reproducibility and sensitivity. The strictness of the PER work load relationship is lowered at higher pedalling rate, especially at 100 rpm. When using the PER scale, pedalling rate has to be considered as an factor of main influence.

Adult↗