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Biomedical subjects

H Lübbe

Publications and source records attributed to H Lübbe.

13 recordsLinked to original sources

[Migration of a retained premolar into the processus muscularis of the mandible].

Migration of an impacted mandibular premolar is a rare finding, whereas dystopia of lower jaw cuspids is described much more often in the literature. We present a patient in whom radiographic studies show the migration of a mandibular premolar to the muscular process over a period of 14 years. Most of the tooth migration along the vertical portion of the mandibula into the processus muscularis took place after the root development had ended. Neither radiological nor clinical examination revealed the stimulus which changed the path and the direction of the impacted tooth.

Adult↗

[Acceptance: scientific cultural aspects].

In highly developed industrial societies the acceptance of risk is in decline. The reasons for this are connected in elementary fashion with the fact of modern life. Their effects may be considered irreversible, and pep talks under the motto "dare to risk!" are probably of no avail; we must adapt ourselves to declining risk acceptance. What are the reasons for it?

Culture↗

[Not Available].

Explore the source record for details and available documents.

Germany↗

[Growth of the jaw after preoperative orthodontic treatment of cleft lip and cleft palate].

In 48 patients a systematized therapeutic model plan for the preoperative and postoperative orthodontic treatment of patients with unilateral or bilateral cleft lips and palates is pursued. In addition to stimulation and growth control of the maxillary alveolar segments in a transverse direction and at the segment poles, increasing sagittal development is observed in a later developmental phase.

Child, Preschool↗

[Studies on the surgical and chemotherapeutic management of oral cancer].

Of the 101 patients who have been treated with bleomycin since 1971 two groups were formed: Group I: Preoperative chemotherapy with 345 mg bleomycin, followed by radical operation. Group II: 200 mg bleomycin preoperatively, followed by radical operation and postoperative chemotherapy up to a total dose of 345 mg bleomycin. 1. Bleomycin- induced cellular alterations showed a dose-time relation. 2. The treatment plan for group II with 200 mg bleomycin preoperatively plus postoperative cytostatic therapy up to a total of 345 mg resulted in less recurrences and fewer distant metastases than the sole preoperative application of the full dose of 345 mg bleomycin. 3. In all cases, preoperative microscopic examination after administration of the full dose of 345 mg still showed tumor cells with possible growth potential.

Bleomycin↗

The NADPH-dependent cytochrome P-450 reduction in liver microsomes of rats of different ages with and without phenobarbital pretreatment.

The activity of NADPH-cytochrome P-450 reductase in liver microsomes of 10- to 60-day-old rats was determined. Neither the half life time of cytochrome P-450 reduction nor the absolute amount of cytochrome P-450 reduced per time unit depend on age. Phenobarbital pretreatment enhances the reduction rate in all age groups. The addition of hexobarbital or ethylmorphine to microsomal suspension accelerates the reduction of cytochrome P-450 in some age groups only. Age differences corresponding to developmental changes in drug-metabolizing activities are not detectable. The NADPH-cytochrome P-450 reductase seems to be not responsible for the age dependence of drug metabolism.

Animals↗