Biomedical subjects
H Lamki
Publications and source records attributed to H Lamki.
Bilateral ovarian cysts with squamous intraepithelial neoplasia.
We report a case of bilateral ovarian cysts lined exclusively by squamous epithelium showing multifocal intraepithelial neoplasia. The cervix showed synchronous high-grade intraepithelial neoplasia (CIN III). We interpreted the ovarian lesions as squamous carcinoma of borderline malignancy and believe that they are part of a "field change" that also involves the cervix.
Pregnancy complicated by maternal heart disease. A review of 519 women.
Between 1970 and 1983, 519 pregnancies in 405 women with heart disease were managed at the Royal Maternity Hospital, Belfast, Northern Ireland, a rate of 1.3 per 100 deliveries. In 312 (60%) the heart disease was of rheumatic origin, in 161 (31%) congenital, and the remaining 46 (9%) were a miscellaneous group that included arrhythmias, ischaemic heart disease and cardiomyopathies. The New York Heart Association (NHYA) grading was no greater than 1-2 in 445 (86%) pregnancies antenatally. Three maternal deaths occurred, all in the group whose antenatal NYHA grade was 3-4. Heart failure was present in 96 (18%) pregnancies antenatally, and six others developed failure during labour or in the puerperium. Prophylactic antibiotics were not used routinely and infective endocarditis did not occur. The perinatal mortality rate was 19/1000, and the rate of congenital malformations was not raised in the reviewed group.
Metastatic germ cell tumour associated with XY gonadal dysgenesis: successful chemotherapy. Case report.
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Carcinoma-in-situ of the cervix and vulval warts complicating malignant lymphoma.
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The prognostic value in threatened abortion of plasma progesterone values and the cornification index of vaginal smears.
The predictive values of plasma progesterone levels in 70 patients threatening to abort was investigated. It was found that no patient aborted whosed plasma progesterone level remanined above 35 nmol/l between 7 and 16 weeks of pregnancy, whereas if the plasma progesterone level was less than this, subsequent abortion always occurred. The predictive value of cornification index in vaginal smears was also examined: many smears were unsatisfactory for assessment and in patients with threatened abortion there was a 14 per cent incidence of falsely optimistic and 29 per cent of falsely pessimistic predictions.
Hepatic-cell adenoma presenting with intraperitoneal haemorrhage in the puerperium.
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A study of plasma diazepam levels in mother and infant.
A 10 mg dose of diazepam was given intravenously to mothers at 15 to 205 minutes before delivery, and plasma diazepam concentrations were measured by gas-liquid chromatography in mothers and infants at delivery and again 24 hours later. The plasma levels in the infants were always significantly higher than in the mothers but there was no evidence to suggest that the newborn were unable to metabolize the drug. All infants had a good Apgar score at birth.
Induction of labour by prostaglandin E2 compared with Syntocinon.
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Induction of labour with oral prostaglandin E2.
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