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H Lanfermann

Publications and source records attributed to H Lanfermann.

76 records · Page 5Linked to original sources

[The value of computed tomography for the staging of esophageal carcinoma].

64 patients were operated on for carcinoma of the oesophagus during a five-year period (1/83 to 1/88) at the Department of Surgery of the University of Cologne; 95.3% of these suffered from squamous cell carcinoma. A preoperative CT of the thorax was performed in 38 patients, 13 of whom underwent abdominothoracic surgery and 25 blunt oesophagus dissections. The CT and plain diagnostic results were compared retrospectively and postoperatively with the intraoperative or histological findings. Three of seven oesophageal carcinomas of up to 2 cm size were not identified by CT. Infiltration of adjacent mediastinal structures by T3 carcinomas was detected in 16 of 22 cases with 3 false positive findings. In blunt oesophagus dissection the preoperatively diagnosed lymph node status agreed with the histological findings in more than 80% of the cases; a limitation, however, was the fact that only those lymph nodes could be assessed that clung to the resectate. In contrast, agreement was seen in only 7 of 13 cases (with 6 false negative findings) after abdominothoracic resection of oesophageal carcinomas. On the whole, there was agreement between preoperative and histological staging according to the TNM classification (UICC = in 50% of the cases, whereas in almost 40% (n = 15) the size or extension of the tumour growth had been underestimated preoperatively. Hence, the value of CT for the preoperative staging of oesophageal carcinoma is restricted.

Aged↗

[Diagnosis of intracerebral aneurysms].

Even today intracerebral aneurysms are a diagnostic challenge. CT is still the method of choice in the acute phase of subarachnoid haemorrhage. In later stages potential results of aneurysmal bleeding like oedema and infarction are better detected by MRI. Selective arteriography remains an obligatory element of radiologic diagnosis preoperatively and in cases of possible interventional proceedings. A synthesis of all methods ensures high diagnostic accuracy.

Aortic Dissection↗

Central nervous system lymphoma in children.

This paper describes the rare MR and CT features of central nervous system (CNS) lymphoma in immunocompetent children and in survivors of childhood acute lymphoblastic leukemia (ALL) and discusses the causative role of cranial irradiation and/or leukoencephalopathy preceding central nervous system (CNS) lymphoma in survivors of childhood leukemia. The authors reviewed MR and CT scans of 3 children with biopsy-proved CNS lymphoma. One child had tumor infiltration within the optic nerve sheaths and optic chiasm by previously known non-Hodgkin lymphoma. In 2 patients, CNS lymphoma developed 8 and 10 years after initial ALL treatment. In both cases CNS lymphoma was preceded by cranial irradiation and leukoencephalopathy. A single lesion was present in 3 out of 4 patients. All lesions were isointense or hypointense on the T1-weighted images relative to gray matter and showed homogeneous enhancement. One lesion was centered in the central gray matter, one lesion was centered within a cerebral hemisphere, one lesion was in optic nerve, and there were 2 parasellar lesions. CNS lymphoma has a variable appearance in children. Knowledge of risk factors in children may help in the early recognition of disease, allowing for timely intervention. This may prompt early biopsy or a conservative management in the appropriate clinical setting.

Adolescent↗

Functional MRI of language-related activation in left frontal schizencephaly.

Brain activation associated with covert verb generation was studied in a right-handed patient with an asymptomatic left frontal schizencephaly by functional magnetic resonance imaging. Activation of the dysplastic neuronal tissue lining the cleft and the adjacent cortex was found, indicating participation of the malformed region in physiologic cerebral functions. This finding may have clinical impact in patients with medically intractable seizures due to malformations of the cortical development prior to epilepsy surgery.

Adult↗