Biomedical subjects
Publications and source records attributed to H Langhorst.
Inborn abnormalities of the lung are rarely seen by clinicians. This paper reports about the cases obeyed within a ten-years-space in a lung-clinic. Symptoms, diagnostic procedure, and treatment are described.
In 124 patients with Crohn's disease (69 women, 55 men; mean age 33.7 [11-66] years) and 53 with ulcerative colitis (30 women, 23 men; mean age 36.2 [19-74] years) the incidence of lactose intolerance, as measured by the H2 breath test and blood sugar concentration, was determined prospectively. To exclude abnormal bacterial colonization of the small intestine or rapid small-intestine transit after partial resection of the small intestine as a cause of lactose intolerance, the oro-caecal transit time for lactulose (H2 breath test) was measured. While 21 of 124 patients with Crohn's disease (16.9%) had the expected incidence of lactose intolerance, this was present in only 2 of 53 patients with ulcerative colitis (3.8%; P < 0.05). The lactose intolerance was independent of the site of any inflammatory changes, disease activity and extent of small-intestine resection. Oro-caecal transit time for lactose was similar for all patients. There was no lactose intolerance in two patients with abnormal small-intestinal bacterial colonization.--Because of their considerable diagnostic and prognostic significance, tests for lactose intolerance should be performed routinely in all cases of Crohn's disease or ulcerative colitis.
Benign tumors of the lung are infrequent diseases. Their symptoms depend on their localisation in the periphery of the lung or in the central airways. Cough, hemoptysis, and dyspnoea are the most frequent symptoms, they should cause further diagnostic investigations (X-ray in two directions, bronchoscopy). This paper shows the frequency, symptoms, diagnostic procedure and findings, and the treatment of benign lung tumors, giving a survey of the patients of a pneumologic clinic during ten years.
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