Biomedical subjects
Publications and source records attributed to H Le Bars.
Spontaneously leukemic AKR mice were exposed from 6 weeks age to a 50 kV/m electric field 12 hrs./day. In this study, carrying on 50 exposed and 50 sham-exposed mice, like in the two preceding experiments, the exposed group mortality is lightly retarded, and reaches 100% only 10 weeks after the sham-exposed group. These differences are not however statistically significative.
In healthy adult goats, closure of the esophageal groove was induced by thirst, IV administered vasopressin, and intracarotid administration of hypertonic NaCl solutions. The efficiency of stimulation was tested directly by visual inspection of the course taken by orally administered solutions through a ruminal or abomasal fistula, palpation of the lips of the esophageal groove through a ruminal fistula, and indirectly by following the glucose dynamics in the blood after oral administration of glucose solution. Esophageal groove closure was observed during drinking after a 48-hour period of water deprivation. Intracarotid administration of 1.5 ml of a saturated solution or 10.5 ml of a 1.5% solution of NaCl also stimulated groove closure; however, groove closure stimulated by administration of vasopressin is the most satisfactory procedure for passing compounds of therapeutic importance directly from the cardiac orifice to the abomasum.
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Oral toxicity of an oily preparation of carbon tetrachloride is considerably lowered by association with NN' diphenyl-p-phenylene diamine according to a given ponderal ratio with CCl4. The results are discussed with regard to the other authors' reports.
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