Dissection of the prostatic apex for radical cystectomy and detubed ileocystoplasty.
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Biomedical subjects
Publications and source records attributed to H Le Doze.
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Intractable bleeding occurred in patient who has his inflated balloon catheter accidentally torn out. Treatment by bilateral transcatheter embolization of the hypogastric arteries was successful. The indications, technical requirements and complications of this method are reviewed.
A procedure of small endoscopic nephrolithotomy during open surgery for staghorn calculi is described. This procedure is based on the principle of percutaneous nephrolithotomy. Same instruments are used. These endoscopic nephrostomies are less traumatic.
The authors present two well documented cases of extensive acquired stenosis of the infra-pelvic upper urinary tract following percutaneous nephrolithotomy. This type of complication appears to be exceptional as, by combining the series of two centres, it represents only two cases out of more than five hundred cases treated. The delay in appearance is of the order of six months. The more or less complex nature of the procedure does not appear to be responsible. It is difficult to determine the exact mechanism fo this complication: several hypotheses are proposed. A few rare cases have been reported in the literature without raising any particular attention. These complications required difficult reconstructive surgery with a good result in both cases. Although these complications seem to be difficult to prevent, they should be systematically detected by ultrasonography at two months and at six months to avoid delay in the diagnosis of functional renal exclusion.
The visualisation of the lower urinary tract by the mean of a fiberscope makes an advance when compared to rigid endoscopy mainly in male patient. Technical features of the fiberscopes suitable for urology thus basic technique of the examination are described. Main advantages are painfree and total visual scanning of the mucosa. Disadvantages are very low.
The authors report their experience of percutaneous nephrolithotomy over a period of three years. The analysis of the first 250 cases performed reveals a low morbidity, with serious complications in 1% of cases, and an acceptable complete success rate of 83%. The indications for percutaneous nephrolithotomy have been modified since the opening of an extracorporeal lithotripsy unit. The choice between the two techniques depends on their efficacy and their expected morbidity based on four criteria: the volume, chemical composition and site of the stone and the morphology of the upper urinary tract. Percutaneous nephrolithotomy is the treatment of choice for large stones (greater than 2.5 cm), hard stones or those formed proximally to a stenotic lesion of the urinary tract, which can then be dilated at the same procedure. A combination of the two methods is sometimes uses to treat staghorn calculi with a success rate of 80%. On the other hand, very large staghorn calculi with caliceal branches are best treated by open surgery.
Owing to its considerable effectiveness, modern multiple chemotherapy ranks first in the treatment of non-seminoma metastatic tumours of the testis. Its side-effects in short-term treatment are recognized and acceptable in view of the results obtained, but they remain imperfectly known in long-term treatments. Fort this reason, the present tendency in clinical stage I non-seminoma tumours is to reserve chemotherapy for patients who relapsed after orchidectomy. Advanced seminomas with or without high levels of human chorionic gonadotrophin (subunit beta) already benefit from chemotherapy, and this treatment is likely to be extended to less disseminated forms of cancer. Pure or predominant choriocarcinomas still respond poorly to the cytotoxic drugs at present available.
A.F.P. and B.H.C.G. serum levels were measured using a radio-immunoassay in 22 patients with a N.S.G.C.T.T. before and 15 days after orchidectomy. The results were confronted to the stage of the disease as determined by R.P.L.N.D. in the absence of gross metastatic disease. 4 of 6 patients with normal tumor markers had stage II or III disease, and 2 of 7 in whom the markers returned to normal were stage II. Pre-orchidectomy A.F.P. levels over 100 ng/ml are consistent with metastatic disease as well as vascular and/or cord involvement irrespective of the markers status. These results should be born in mind when deciding a simple surveillance policy in clinical stage I N.S.G.C.T.T. Serum tumor markers, alfa foetoprotein (A.F.P.) and the B fraction of human choriogonadotropin (B.H.C.G) are commonly used to monitor surveillance as well as therapeutic response in patients with N.S.G.C.T.T. It is however well known that 30% of the patients with stage IIa, IIb, N.S.G.C.T.T. have normal post-orchidectomy serum markers (SKINNER). These false negative which may proceed from absence or undetectable tumor markers secretion by the metastases, question the safety of the wait and see policy based on serial serum markers determination as well as abdominal and thoracic C.T. Scan. Nevertheless, the level of pre-orchidectomy serum tumor markers as well as their evolution after orchidectomy may be more meaningful.
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The authors report a series of forty patients presenting with vesicorenal reflux treated by ureteral reimplantation. Seventeen ureterorenal units were treated by Hutch's procedure, with a success rate of 75%. In 1972, this procedure was abandoned in favor of Cohen's technique, and a further forty two ureterorenal units were treated with a 90% success rate. There was no recurrence of the reflux, but there was one case of stenosis.