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Biomedical subjects

H Leighton

Publications and source records attributed to H Leighton.

5 recordsLinked to original sources

Effect of endotracheal suctioning on the intracerebral haemodynamics of patients in fulminant hepatic failure.

Fulminant hepatic failure is a severe impairment of liver function in someone who has had previously normal liver function. The patients presenting to intensive therapy units have generally had a rapid deterioration which requires prompt intervention and treatment. The first part of this paper gives a detailed review of the aetiology, physiology and management of the disease process. Medical and nursing care of these patients is critical; any adverse intervention may affect outcome. A literature review and small study of the intervention of endotracheal suctioning and its effects on intracranial pressure and cerebral perfusion pressure is described.

Acute Disease↗

Paracetamol poisoning: a case study.

Over a 1-year period, 24 patients have been admitted to one intensive therapy unit (ITU) with fulminant hepatic failure secondary to paracetamol poisoning. This article reviews one such case and the subsequent management which led to successful transplantation, concentrating on the clinical and nursing implications of the patient's care.

Acetaminophen↗

Maintaining the patency of transduced arterial and venous lines using 0.9% sodium chloride.

Using dilute concentration of heparin in continuous flush systems for arterial and venous invasive cannulae is an established practice in intensive care units (ICUs) throughout the UK. It is, however, practical to maintain the patency of these lines using 0.9% sodium chloride, thus reducing the possibility of drug interactions, systemic anticoagulation and cost. A small feasibility study was carried out in a 10-bedded general ICU on both arterial and venous lines using 0.9% sodium chloride over a 3-month period. The study has subsequently changed unit policy.

Catheterization, Peripheral↗