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Biomedical subjects

H Lennartz

Publications and source records attributed to H Lennartz.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Successful therapy of accidental deep hypothermia].

A case of extreme accidental hypothermia to 23,5 degrees rectal temperature in a 79 years old female with a skull-brain-trauma is reported. Under continuous monitoring and maintenance of vital functions, we succeeded by means of slow surface rewarming in prevention of noxious side effects on the circulatory system. The favourable course during the rewarming process probably was due to elimination of thermoregulation in brain trauma. The patient had a good longterm out-come.

Aged↗
PubMed1983

[Effect of neuroleptanalgesia on operation-induced rise in the antidiuretic hormone].

Plasma-levels of antidiuretic hormone were measured in patients undergoing major abdominal surgery pre-, intra- and postoperatively. All patients (n=20) received neuroleptanalgesia as anaesthetic procedure; 10 of them received etomidate additionally. Initial value of vasopressin as well as values after induction of anaesthesia stayed within normal range in all patients. The operation period was accompanied by elevated ADH-levels with a maximum of 500% above initial values. 5 patients having been antagonized postoperatively with naloxone 0.005 mg/kgbw showed marked increase in ADH-level. In comparison to former investigations we conclude that NLA can not block stress-induced rise in vasopressin-concentration effectively as seen under the combination of NLA plus epidural analgesia.

Abdomen↗
PubMed1982

Plasma histamine levels in patients in the course of several standard operations: influence of anaesthesia, surgical trauma and blood transfusion.

A prospective controlled clinical trial was conducted on changes in plasma histamine and catecholamine levels during 5 standard operations. This communication, as the first part of the trial, deals only with the feasibility of such a trial and the changes in plasma histamine levels. Elevated histamine concentrations corresponding to histamine-release responses of greater than 1 ng/ml occurred in 8 of 25 operations. In an explorative analysis these responses were associated with distinct phases of anaesthesia or the surgical procedure. Blood transfusion carried the risk of infusion of "free histamine" into the patient--especially when administered under pressure. Since during operations "free histamine" enters the circulation with a rather high incidence and may cause harmful effects, premedication with H1-+H2-receptor antagonists seems worth consideration.

Adult↗
PubMed1982

[Peridural anesthesia and analgesia results in general surgery].

Anesthesia for major general surgery should involve the use of anesthetic techniques that might reduce the risk of intraoperative and postoperative complications. The combination of intraoperative epidural anesthesia with local anesthetics (EPA) and the use of epidural opiates for postoperative pain relief shows advantages over the application of pure general anesthesia and over postoperative systemic analgesia. Epidural opiates lead to better quality analgesia with a quicker onset and longer duration than systemical analgesics. The spirographic parameters of ventilatory function PF, FVC, FEV [1], paO2, and paCO2 decreased significantly (p less than 0.05) compared with preoperative values when systemic analgesia was performed. After epidural opiates no significant decrease could be seen. Intraoperative use of EPA has the advantages of better hemodynamic conditions and a blockade of the endocrine-metabolic response to surgery. Postoperative peridural opiates block the endocrine response as well: the serum levels of ADH and cortisol are lower than under systemic analgesia.

Anesthesia, Epidural↗
PubMed1982

[A Draeger-universal ventilator with an extended capacity of ventilation].

We have compared an improved Draeger universal ventilator (UV 1) with the corresponding standard model. The improvement was carried out by Draegerwerk according to our directions. The improved equipment is able to provide an increased minute volume (about 50%) and increases, therefore, the respiratory reserve for problem patients.

Humans↗
PubMed1981

[Plasma antidiuretic hormone level as an indicator of perioperative stress (Part I) (author's transl)].

The secretion of antidiuretic hormone (ADH) is mainly influenced by changes in osmolality and blood volume. In addition stress and surgical trauma may cause an elevation in plasma-ADH levels. In 20 patients scheduled for similar surgical procedures two different anaesthesia techniques were applied: in group 1 (n = 10) a combination of peridural anaesthesia and neuroleptanalgesia (PDA/NLA) was performed, in group 2 halothane anaesthesia with intubation was used. The perioperative control of plasma-ADH levels demonstrated a smaller increase in group 1 (PDA/NLA) compared to group 2 (Halothane), thus implicating a better attenuation of stress and pain.

Adolescent↗
PubMed1981

[Plasma-antidiuretic hormone level as indicator of postoperative stress (part II) (author's transl)].

For a period of five days serum levels of antidiuretic hormone (ADH) have been investigated postoperatively in a group of 20 patients with upper abdominal surgery. In addition serum electrolytes (Na+, K+) and plasma osmolality have been controlled regularly. Patients in group A (n = 10) received Fentanyl epidurally (0.1-0.2 mg diluted with 0.9% saline solution) for treatment of postoperative pain, whereas in group B (n = 10) systemic opiate therapy was performed by intramuscular application of piritramide (Dipidolor, 15-25 mg). There was a significant increase in ADH in all patients, whereas serum electrolytes (Na+, K+) and plasma osmolality stayed within normal range. ADH-levels in group A (epidural opiate), however, were significantly lower than mean values in group B (systemic opiate application). The postoperative increase in ADH is interpreted as a reaction to stress and trauma, being less pronounced, when epidural opiate therapy is performed for postoperative pain treatment.

Adult↗
PubMed1980

[Effectiveness of Cendehill vaccine in the prophylaxis of rubella embryopathy (author's transl)].

Recent rubella infection (rubella-specific IgM positive, raised rubella complement fixation reaction and haemagglutination inhibition) could be demonstrated during a prophylactic investigation in early pregnancy in a 19-year-old girl previously successfully immunised with Cendehill vaccine (seroconversion). Due to the seroconversion demonstrated during school age no interruption was performed. The newborn baby had a rubella-HAI-antibody titre in the umbilical blood of 1 : 640, but no rubella-specific IgM antibodies (also at later controls). Rubella infection of the child in utero could thud be excluded. This for the first time confirms the protective effect of the Cendehill vaccine in the prophylaxis of rubella embryopathy.

Antibodies, Viral↗
PubMed1979

[Hemolysis in ger test -- an alternative to hamagglutination inhibition test for search of antibodies against rubella virus (author's transl)].

640 sera of unknown immune status were tested in the rubella hemagglutination inhibition test (HI) as well as in hemolysis in gel test (HIG). The results have been analysed by statistical methods. The reproducibility of zones of hemolysis are 1.7 mm for the long term precision and 1.0 mm for the short term precision. Comparing the HIG and the HI tests we had a correlation of 97% = sensitivity (544 out of 561 sera) in positive reacting sera and of 87% = specifity (69 out of 79 sera) in the negative reactions. We consider a person to have antibodies against rubella if the zone of hemolysis had a diameter of 8 mm or above. In cases of diameters under 8 mm the results of IH and HIG-tests do not correlate. The reasons are not completely known and should be investigated.

Antibodies, Viral↗