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PubMed2001

Recreational water safety in Wisconsin.

Due to Wisconsin's numerous lakes and rivers, tourists and residents alike frequently participate in water-related recreation. Unfortunately, drowning is a leading cause of injury-related death, especially in children and young adults. Developmental factors place children who are less than 5 years at increased risk for drowning. Teenagers also have a higher drowning mortality rate, largely due to risk-taking behaviors in this age group. This article reviews drowning mortality trends and statistics for Wisconsin and the United States, as well as current recommendations and legislation regarding water safety. We also discuss drowning prevention strategies such as patient education and legislative efforts surrounding swimming pool and boating safety.

Adolescent↗

PubMed1990

["Computer-assisted psychodiagnosis with COMBITEST 2 using MS-DOS"].

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Artificial Intelligence↗

PubMed1990

[Action and reaction elements as performance-modifying components of computer use in clinical psychology].

Application of computerized equipment in psychodiagnosis and cognitive training entails novel methodical aspects which relate to design of operator and response controls as well as to the test configuration. Some of these aspects are discussed.

Attention↗

PubMedDate not supplied

Associations of the bacterial mutagenicity of halogenated 2(5H)-furanones with their MNDO-PM3 computed properties and mode of reactivity with sodium borohydride.

Electrophilicity as a general basis for both the mutagenicity and nucleophile inactivation of halogen-substituted 2(5H)-furanones was tested. Lowest unoccupied molecular orbital (LUMO) energy levels and stabilities of 2(5H)-furanone radical anions and C-2, C-3, and C-4 anionic hydride adducts were computed with MNDO-PM3 for each of 10 compounds. These three computed sets of values were considered electrophilicity indicators. Each individual value from a given indicator set was plotted against the logarithm of the Salmonella typhimurium (TA100) mutagenicities (log Mm) for each of the corresponding compounds. Highest occupied molecular orbital (HOMO) energy levels for the 10 compounds were also computed. Strong negative correlations were obtained from the plots of LUMO and radical anion stability against log Mm of the 10 compounds. Also, a negative correlation was observed for the plot of the stability of the C-4 anionic hydride adduct for a smaller set of six compounds possessing a 4-(chloromethyl)-2(5H)-furanone structure and having the same HOMO characteristics. HOMO energies failed to correlate with mutagenicity. Neither computed atomic charge nor 13C chemical shift values for the larger compound group of 10 correlated well with mutagenicity or with each other. Sodium borohydride and borodeuteride reductions of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone demonstrated experimentally that hydride became attached to C-4.

4-Butyrolactone↗