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Biomedical subjects

H Lincke-Plewig

Publications and source records attributed to H Lincke-Plewig.

7 recordsLinked to original sources

[Spreading pigmented actinic keratosis--diagnosis and therapy].

Spreading pigmented actinic kereatosis is a rarely described premalignant epidermal lesion occurring on the skin following exposure to the sun. On clinical examination it may be difficult to distinguish it from pigmented seborrheic keratosis or lentigo maligna. Spreading growth and a diameter greater than 1.5 cm are characteristic features. We report a case of spreading pigmented actinic keratosis in a 61-year-old patient.

Facial Neoplasms

[Lichenoid keratosis].

Lichenoid keratosis is a usually solitary skin lesion occurring in sun-exposed areas. It is macroscopically uncharacteristic, resembles actinic keratosis, basal cell epithelioma, Bowen's disease, or flat seborrheic keratosis, but shows histologically the typical pattern of lichen planus. Lichenoid keratosis should be differentiated from the lichenoid variant of actinic keratosis.

Aged

[Bleomycin exanthema].

Four patients were observed which developed cutaneous side effects during treatment with bleomycin. The bleomycin rashes appeared after 10 to 14 days of therapy and a cumulative dose of 120 to 150 mg.

Adult

[Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp].

The clinical differential diagnosis between seborrheic dermatitis and psoriasis vulgaris of the scalp can be difficult. We, therefore, tried to elaborate histopathological criteria for a differentiation of the two dermatoses. Forty excisional biopsies were analysed without knowing the clinical diagnosis. The histopathological substrate within the epidermis is characterized in psoriasis by dermatitis-like and in seborrheic dermatitis by psoriasis-like alterations. Therefore, in some cases a definite histopathological diagnosis could not be made. Strong criteria favouring psoriasis are: moderate condensed hyperkeratosis with alternating parakeratosis, PAS-reactive serum inclusions and Munro abscesses within the horny layer, spongiform pustles and neutrophilic leukocytes within the epidermis. Strong criteria for seborrheic dermatitis are: irregular acanthosis with relatively thin condensed orthoor parakeratotic horny layer, spongiosis and spongiotic vesicles, exocytosis of lymphocytes and the lack of any hard criterias for psoriasis. The results may suggest that seborrheic dermatitis of the scalp may transform into psoriasis in patients with a genetical disposition ("psoriatic diathesis", "latent psoriasis") via a Köbner reaction. The existence of the seborrheic dermatitis (Morbus Unna) is not doubted by these investigations.

Biopsy