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Biomedical subjects

H Lincoff

Publications and source records attributed to H Lincoff.

At least 73 records · Page 4Linked to original sources

Color vision and other parameters of macular function after retinal reattachment.

Patients with a preoperatively detached macula and operated upon between October 1976 and July 1978 were analyzed for three parameters of macular function after surgical repair. Reattachment was achieved by cryopexy, an external sponge plombage and nondrainage. The observation period was a minimum of 1 year. Visual acuity increased in all patients with a maximum improvement in the first 3 months after macular reattachment. Color vision was postoperatively defective in every second patient. In the majority of cases it was a trito disturbance. The disturbance in color vision was most prominent in patients over 60 years old. During the period of 1 year, normalization of color vision occurred for the most part only in patients under 60 years of age. Metamorphopsia proved to be the most sensitive indicator of an episode of previous macular detachment. It occurred in every patient independently of age and was still present at the end of 1 year. It could be considered as a 'scar in the Amsler grid.' The occurrence of metamorphopsia was independent of whether subretinal fluid was drained or allowed to absorb spontaneously.

Adult↗

Intravitreal longevity of three perfluorocarbon gases.

Three gases, perfluoromethane, perfluoroethane, and perfluoropropane (CF4, C2F6, and C3 F8, respectively) were studied for their possible value as intravitreal tamponades in retinal surgery. The gases expand and have intraocular longevities that increase with the length of the carbon chain. A 0.4-cc injection of CF4, remained in the eye six days, twice as long as an equivalent amount of air; C2F6 remained 16 days, more than four times as long as air; and C3F8 remained 28 days, nine times as long as air and four times as long as sulfur hexafluoride.

Air↗

Additional indications for a temporary balloon buckle.

An operation for small retinal detachments that uses a balloon-tipped catheter as the buckling device was described in October, 1978. The balloon is inserted into Tenon's space through a small incision in the conjunctiva and is manoeuvred beneath the retinal break. Expansion of the balloon produces a buckling effect that causes the subretinal fluid to absorb. The balloon is withdrawn after 1 week. Permanent attachment is obtained by transconjunctival cryopexy around the break at the time of insertion or laser coagulation after the retina has re-attached. The balloon operation has become a preferred technique at the New York Hospital and has been used in 93 patients. Application is limited to retinal detachments caused by a single retinal break or group of breaks that together subtend less than one clock hour and that are located in the anterior two-thirds of the globe. The extent of the detachment has not proved to be a limiting factor.

Diplopia↗

An elastic pouch operation for large retinal tears.

An episcleral pouch operation that uses Dacron-reinforced silicone sheeting for the patch and silicone sponge pellets for the stuffing has been used to extend the localized radial buckling technique to retinal detachments that are caused by breaks that span a circumferential arc between 40 degrees and 70 degrees. Nineteen of 20 retinal detachments responded favorably to the operation, 14 without drainage of subretinal fluid. When the pouch was extended circumferentially to apply to detachments caused by breaks greater than 70 degrees, it failed in six of seven patients because a radial configuration could no longer be maintained. The substitution of transparent silicone sheeting for donor sclera facilitates the fitting and stuffing of the pouch.

Adolescent↗

Infection after sponge implantation for scleral buckling.

In one series of 900 explant scleral buckling procedures, 31 had to be removed over seven years because of contamination. Of 1,000 explants from a parallel series, 27 had to be removed. In the second series, requirement of a sterile conjunctiva preoperatively and the use of prophylactic antibiotics postoperatively did not significantly reduce the rate of infection.

Bacterial Infections↗

Other advances in chorio-retinal surgery. A comparative study of sponge infections.

During a period of seven years out of 900 explant operations done in New York 31 sponges had to be removed. In Bonn during the same period a comparable 27 explants out of 1000 operations had to be removed. Clinical infection occurred as early as one week and as late as seven years after the operation. The infection of the sponge manifested as: fistula, granuloma or a subconjunctival haemorrhagic mass. 2/3 of the infections were due to staphylococcus epidermis which acts as a pathogen in the presence of a foreign body. Bonn's requirement of a sterile conjunctiva preoperatively and the use of prophylactic antibiotics postoperatively did not significantly reduce the rate of infection.

Anti-Bacterial Agents↗

Mechanics of intraocular gas.

The relationship between the volume of an intraocular gas bubble and the area of retina covered by the bubble was studied with the use of both a transparent model and a mathematical model of the vitreous cavity. The arc of contact of intraocular bubbles was calculated for vitreous cavities of various diameters. A 0.28 cm3 bubble will cover 90 degrees of retina and be of sufficient size to manage many of the problems for which an internal retinal tamponade would be useful. Larger retinal tears require disproportionately large increases in bubble volume to achieve modest increases in the area of retina covered. Estimating bubble size by observing the height of the bubble meniscus in the dilated pupil is subject to errors induced by small shifts in the angle of observation. A correct evaluation requires that the plane of observation be adjusted so that it coincides with the plane of the meniscus.

Gases↗

Mechanisms of failure in the repair of large retinal tears.

An analysis of large tears treated over a decade revealed that while dialyses responded well to circumferential buckling, horseshoe tears responded poorly. A circumferential intrusion of the globe augmented the redundancy of the posterior edge of long tears and predisposed to leaking radical folds. Tears up to 70 degrees responded favorably to radical buckles, often without drainage of subretinal fluid. Beyond 70 degrees and initial procedure with cryopexy and a gas tamponade without buckling reattached the retina occasionally, and if not, would at least reduce the problem to one manageable by local buckling techniques with a more favorable prognosis.

Cryosurgery↗

[Clinical report of a conservative management in treating acute vitreous haemorrhage (author's transl)].

In the first hours after a vitreous haemorrhage dense enough to obscure the retina, the blood is usually confined to the posthyaloid space in an aqueous phase. Binocular occlusion and elevation provides sufficient immobilization of the eyes in 9 out of 10 patients for the blood cells to settle to the bottom of the space and make the retina available for examination and repair. Is this not done, blood will eventually enter the vitreous gel through holes that develop in the posterior hyaloid membrane. Blood in the gel does not settle and requires months to clear.

Acute Disease↗

Geometry of intraocular gas used in retinal surgery.

The relationship between the volume of an intraocular gas bubble and the area of retina covered by the bubble was studied using both a transparent model and a mathematical model of the vitreous cavity. The arc of contact of intraocular bubbles was calculated for vitreous cavities of various diameters. A 0.28-cm3 bubble will cover 90 degrees of retina and be of sufficient size to manage the majority of problems for which an internal retinal tamponade would be useful. Larger retinal tears require disproportionately large increases in bubble volume to achieve modest increases in the area of retina covered. Estimating bubble volume by observing the height of the bubble meniscus in the dilated pupil is subjected to errors induced by small shifts in the angle of observation. A correct evaluation requires that the plan of observation be adjusted so that it coincides with the plane of the meniscus.

Air↗

Exudative retinal detachment secondary to dislocated lenses.

2 cases of retinal detachment with ectopia lentis are described. In each, the retinal elevations had surface features consistent with exudative detachments. Following removal of the posteriorly displaced lenses spontaneous retinal attachment was noted. The clinical and surgical course of these patients suggest a diagnosis of lens-induced exudative retinal detachment.

Adult↗

Limits of constriction in the treatment of retinal detachment.

A constricting silicone band was added to 13% of local sponge buckle operations in this series. The purpose was to relieve circumferential traction or to maintain a high buckle. The inclusion of a cerclage did not require drainage of subretinal fluid. The rate of reattachment without drainage (42 of 50 detachments) is comparable to what might be expected if the subretinal fluid had been drained. Constriction was controlled and limited to between 10% and 25% of the circumference of the eye. Anterior segment ischemia requiring relaxation of the band occurred in two patients; scleral erosion did not occur.

Animals↗

Radial buckling in the repair of retinal detachment.

Experience with external sponge buckles for the treatment of retinal detachment has led to a preference for radial placement of the sponge. More retinal holes, particularly large horseshoe breaks, can be closed effectively with radially oriented buckles than with limbus parallel ones; limbus parallel buckles often were complicated by "fish-mouthing" of the breaks and leaking radial folds. A radial orientation of the buckle averts this complication. The geometry of retinal detachment and scleral buckling reveals the origin of "fish-mouthing" and radial folds and why radially oriented buckles prevent this complication.

Humans↗