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Biomedical subjects

H Logan

Publications and source records attributed to H Logan.

At least 19 recordsLinked to original sources
PubMed1994

Desire for control, felt control, and stress inoculation training during dental treatment.

Coping style research has typically assessed subjects' desire for a coping resource, but ignored whether subjects possess that resource. In this study 110 dental patients were categorized as to their desire for and feelings of control and were randomly assigned, just prior to dental treatment, to a 20-minute Stress Inoculation Training (SIT) session or a Filler condition. SIT significantly reduced pain and increased control only for patients who initially reported a high desire for control coupled with low perceived control. This finding supports the view that the discrepancy between high desire for control and low perceived control plays a causal role in the elevated distress and pain initially reported by patients with such control perceptions. These data indicate that consideration of patients' perceived coping resources as well as their coping preferences adds to our ability to predict reactions to stress reduction manipulations.

Adaptation, Psychological↗
PubMed1993

Emotional and sensory focus as mediators of dental pain among patients differing in desired and felt dental control.

Giving patients instructions to focus on sensory (vs. emotional) stimuli during a root canal procedure significantly reduced self-reported pain, but only among patients who were classified as having strong desire for control and low felt control in dental situations. Among patients with low felt control and low desire for control, sensory-focus instructions produced greater pain reports than did emotion-focus instructions. Finally, high desire-low felt patients reported higher levels of expected pain before treatment than did other patient subgroups. These data suggested limiting conditions for H. Leventhal's (1982) theory of emotion and supported the idea that desire for control might moderate the effects of perceived control.

Adaptation, Psychological↗
PubMed1992

Breast tumour thymidine kinase levels and disease recurrence.

Thymidine kinase (TK) exists in two forms, TK1 and TK2. TK levels and oestrogen receptor status (OR) were measured in tumours from 86 patients with operable breast cancer and the patients were monitored for recurrence over 24 months. During the monitored period, 13 patients showed recurrence. These patients also exhibited higher total TK levels per mg tumour (P < 0.01) and higher TK1 levels (P < 0.001) than those who did not show recurrence. TK1 levels relative to TK2 were significantly higher (P < 0.05) in OR-negative tumours (n = 29) than in OR-positive tumours (n = 57). OR-negative (n = 9) and OR-positive (n = 4) patients who recurred had significantly higher TK1 levels relative to TK2 than did those who not recur (n = 20 and n = 53, respectively). These preliminary results indicate that breast tumour TK levels may have value in determining prognosis.

Adult↗
PubMed1991

The analysis of 5-fluorouracil in human plasma by gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS) with stable isotope dilution.

5-Fluorouracil (5-FU) was extracted from plasma and converted to its di-N-ditrifluoromethylbenzyl (DTFMBz) derivative by treatment with DTFMBzBr. Under negative ion chemical ionization (NICI) conditions the derivative yielded a mass spectrum in which most of the ion current was carried by the M(-)-DTFMBz ion (m/z 355). Selected ion monitoring enabled detection of this derivative in amounts less than 1 pg, and the practical limit of detection for 5-FU extracted from plasma was ca 400 pg ml-1. 5-FU was quantified by adding a fixed amount of [15N2]5-FU to samples of plasma before extraction, and comparing the ratio of the ions of m/z 355 and 357 against a calibration curve constructed over the concentration range under investigation. The method was used to measure the variation in the concentration of 5-FU with time during continuous infusion of the drug via three, different protocols in patients with hepatic tumour.

Fluorouracil↗
PubMed1991

Development of radiolabelled albumin microspheres: a comparison of gamma-emitting radioisotopes of iodine (131I) and indium (111In/113mIn).

Biodegradable albumin microspheres have been prepared incorporating either 131I or 111In/111In. Using cDTPAA/albumin molar ratios of 1, 3 and 10, approx. 0.7, 2.1 and 7 molecules of DTPA could be coupled to an albumin molecule, labelling efficiency being constant over this range. Because 131I microspheres were more stable in plasma than the system labelled with radionuclides of indium it was selected for clinical evaluation: potential uses of this radiopharmaceutical are illustrated.

Biodegradation, Environmental↗
PubMed1990

Some variables affecting dentists' assessment of patients' distress.

Dental students estimated the pain distress and discomfort of their patients after patients received a Class II restoration (simple filing). Dentist's estimates of patient pain accounted for 36% of the variance in patient self-report responses. Dentist accuracy was significantly lower, however, for estimates of anxiety and distress. Dentist accuracy was unaffected by patient's degree of self-monitoring. There was a tendency for female dentists to demonstrate greater accuracy than male dentists, but this effect was nonsignificant. In addition, dentists' accuracy in assessing overall patient discomfort was significantly lower in that segment of the treatment procedure that was most stressful for the dentists. This article discusses theoretical explanations for this latter effect.

Adult↗
PubMed1989

A comparison of two different T-grain films in rare-earth screens with a standard film-screen combination for intravenous pyelography and bone examinations.

T-grain film is claimed to give significantly improved image quality, allowing the use of faster screens without loss of quality and thus reducing radiation dose. We tested this claim for two systems. In each case comparison was made with our usual screen-film combination, Agfa Curix RP1 film with Kodak Xomatic Regular screens (a nominally 200 speed system). The systems tested were Kodak TMatG in Kodak Lanex Medium screens (300 speed) and Agfa STG in Kodak Lanex Regular screens (400 speed). The Agfa STG-Lanex Regular system performed less well than the standard system for intravenous pyelograms (IVPs), bones and soft-tissue detail. Its speed advantage was not apparent below 70 kV. The Kodak TMatG-Lanex Medium system was better than the standard system for IVPs but not as good for bones. It gave virtually no speed advantage below 90 kV. Kodak T-grain film in a medium-speed, rare-earth screen was found to be better than the standard system for IVPs. Agfa T-grain film in a fast rare-earth screen was unsatisfactory for IVPs. Neither combination was as good as the standard system for bones.

Bone and Bones↗
PubMed1988

Detection of splenosis: 99Tcm tin colloid scanning and computed transmission tomography compared.

Ten patients who had been splenectomized for trauma between 1 and 11 years previously were studied by computed tomography (CT) and radionuclide scanning with 99Tcm tin colloid on the same day. Computed tomography detected splenic tissue in three patients. Radionuclide scanning detected splenic tissue in eight patients, including two cases of typical splenosis not identified by CT. Radionuclide scanning was found to be more sensitive in the detection of residual splenic tissue than CT.

Adult↗
PubMed1987

Simplified peripheral arteriography.

Demonstration of both iliofemoral arteries and their peripheral run-off is usually performed either by the translumbar approach, or by placing a pigtail catheter at the aortic bifurcation. A modified version of the old retrograde pressure method, simply using a cannula in one femoral artery, is described. There was considerable saving in materials, personnel and time. This method may once again be the method of choice in a busy radiology department.

Aged↗