PubMed Health⌕ Search

Biomedical subjects

H Logemann

Publications and source records attributed to H Logemann.

7 recordsLinked to original sources

Onychomycosis in children.

BACKGROUND: Onychomycosis is the most common nail disease in adults. During recent years an increase in its frequency has been reported in children. MATERIALS AND METHODS: Children under 12 years were examined and a clinical diagnosis of onychomycosis was made (Figs. 1-4). Potassium hydroxide (KOH) preparations were made and a fungus culture was done in each case. RESULTS: Twenty-six children with onychomycosis are reported; 16 boys (61.4%) and 10 girls (38.6%). The average age was 8 years. The most frequent variety was distal subungual onychomycosis (88.5%) and the earliest sign was distal subungual hyperkeratosis. The agent most frequently isolated was Trichophyton rubrum which was found in 18 cases (69.2%). CONCLUSIONS: Onychomycosis in children is not exceptional. Attention should be given to any sign during physical examination to avoid dystrophy of the nails and also to eliminate any source of infection.

Antifungal Agents↗

The recurrent carpal tunnel syndrome.

Sixteen out of 720 patients with carpal tunnel syndrome who had undergone surgery since 1979 were reoperated for a "recurrence" (2.2%). Twelve of these patients had been originally operated on in our department. Thus, our own recurrence rate is 1.7%. Three patients deteriorated following surgery, 6 had an unsatisfactory improvement, and in 7 the symptoms recurred after initial improvement. Eight of the reoperated patients had a predisposing disease (terminal renal insufficiency, insulin-dependent diabetes mellitus, acromegaly). In 10 of the 16 cases the initial operation had been carried out by surgeons in the first three years of training. Reoperation revealed incomplete splitting of the transverse carpal ligament in 10 cases, compression of the median nerve by the scar in 4, injury of the muscular branch in 1, and an anatomical variant as cause of incomplete decompression in 1 patient. "Recurrences" after carpal tunnel surgery are predominantly due to inadequacies of the first procedure. A remarkable number of patients (50%) has predisposing diseases. Interfascicular or epineural neurolysis and complete exposure and neurolysis of the median nerve and its branches is necessary only in cases of recurrence. Their omission at the first surgery does not result in an increased recurrence rate. Our observations indicate that the number of operations for recurrent carpal tunnel syndrome can probably be reduced when the first operation is performed with care and experience. Patients with carpal tunnel syndrome secondary to a systemic disease are particularly at risk.

Acromegaly↗

Plants used in Guatemala for the treatment of dermatophytic infections. 1. Screening for antimycotic activity of 44 plant extracts.

Skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. Through ethnobotanical surveys and literature review 100 plants were detected as being used in Guatemala for the treatment of dermatophytoses. Of these, 44 plants were screened for in vitro activity against the most common dermatophytes (Epidermophyton floccosum, Microsporum canis, Microsporum gypseum, Trichophyton mentagrophytes and Trichophyton rubrum). Results showed that aqueous extracts from 22 of the plants tested inhibit one or more of the dermatophytes. The most commonly inhibited dermatophytes were E. floccosum (43.2%), T. rubrum (36.0%), and T. mentagrophytes (31.8%); the less inhibited were M. canis (22.7%) and M. gypseum (24.0%). Plants of American origin which exhibited anti-dermatophyte activity were: Byrsonima crassifolia, Cassia grandis, Cassia occidentalis, Diphysa carthagenensis, Gliricidia sepium, Piscidia piscipula, Sambucus mexicana, Smilax regelii, Solanum americanum and Solanum nigrescens. Fungicidal and fungistatic activities as well as the minimal inhibitory concentration were demonstrated. These results provide a scientific basis for the use of these plants for the treatment of dermatophyte infections in man.

Antifungal Agents↗