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Biomedical subjects

H Lumerman

Publications and source records attributed to H Lumerman.

At least 19 recordsLinked to original sources

Benign fibrous histiocytoma of the maxilla.

Benign fibrous histiocytomas of bone are unusual neoplasms that often are confused with metaphyseal fibrous defects. Although the two lesions have overlapping microscopic characteristics, they differ in their clinicopathologic presentations. This report describes the clinicopathologic features of the first reported case of benign fibrous histiocytoma involving the maxilla and the fourth description of this tumor in the jawbones. In addition, the concept of fibrohistiocytic lesions of bone is discussed with consideration of their pathologic classification and their clinical, radiographic, and microscopic differential diagnosis.

Adolescent

Oral Kaposi's sarcoma: a clinicopathologic study of 23 homosexual and bisexual men from the New York metropolitan area.

A total of 3970 cases of Kaposi's sarcoma (KS) associated with the acquired immunodeficiency syndrome had been reported to the Centers for Disease Control by the end of 1986. The prevalence of oral KS in patients with KS of the skin varies, reaching a maximum of 44% in one published study. We present a retrospective clinicopathologic analysis of 23 previously unreported cases of oral KS in male homosexual and bisexual patients from the New York metropolitan area. Our data reveal that 21 of the patients had KS confined to the oral cavity and that, in 16 cases, the oral KS was the first presenting sign of the acquired immunodeficiency syndrome. Sixteen of the 23 patients had solitary oral lesions. Nineteen of the tumors showed prominent endothelium-lined capillaries resembling lymphatics, 16 exhibited a prominent spindle cell component, and 17 demonstrated areas of fibrosis. Of the 13 patients for whom there was adequate follow-up information, five were dead within 6 to 15 months. All five deaths were due to Pneumocystis pneumonia.

Acquired Immunodeficiency Syndrome

Recurrent botryoid odontogenic cyst (lateral periodontal cyst).

The terms botryoid odontogenic cyst and lateral periodontal cyst have both been used to describe a histologically distinct type of cyst characterized by a thin epithelial lining exhibiting focal thickenings or plaques. The cyst reported herein is a well-documented example of this type of cyst, which exhibited persistent and recurrent behavior.

Adult

Acute promyelocytic leukemia appearing as spontaneous oral hemorrhage: report of case.

Oral signs and symptoms may often signify a serious underlying systemic disease. This case report describes a 45-year-old Oriental male with spontaneous oral hemorrhage and submucosal bullae of 4 days' duration. These oral findings represent the initial manifestations of acute promyelocytic leukemia. An aggressive postdiagnostic course was taken; however, the patient died 8 days after the diagnosis was established.

Diagnosis, Differential

Pigmentation of the jawbones and teeth secondary to minocycline hydrochloride therapy.

Oral pigmentation due to minocycline hydrochloride (Minocin) therapy is an unusual and infrequently reported side effect of the drug. This report describes a patient on long-term minocycline therapy who presented with gingival pigmentation. Upon surgical exploration, the gingiva was noted to be normal in color, but the underlying bone was deeply pigmented. Via fluorescent microscopy, minocycline deposition within the alveolar bone was demonstrated.

Adult

Munchausen's syndrome: report of case.

A patient with Munchausen's syndrome received treatment from at least 25 dental practitioners in the New York metropolitan area. The patient and the syndrome are described to alert the dental community about this patient who is still presumed to be living in the New York area.

Adult

Gingival hyperplasia associated with nifedipine therapy. Report of a case.

A case of gingival hyperplasia associated with the administration of nifedipine is reported. Clinically and histologically, the tissue resembled that seen in hyperplasia induced by phenytoin (Dilantin). We believe this to be the first reported case of gingival hyperplasia associated with this drug.

Female

Proliferative myositis of the masseter muscle. A case report and a review of the literature.

A case of proliferative myositis of the masseter muscle in a 62-year-old woman is presented and pertinent literature is reviewed. This benign pseudosarcomatous proliferative lesion has not been previously reported in any of the muscles of mastication. Clinically the patient presented with pain and difficulty in opening of the mouth. On initial examination, a malignant salivary gland tumor was suspected. The proliferative myositis exhibits a disturbing microscopic appearance characterized by the presence of numerous hyperchromatic fibroblasts and oval or spindle-shaped giant cells which resemble malignant rhabdomyoblasts. These lesions have been often misdiagnosed as rhabdomyosarcoma and other types of sarcomas. Awareness of the microscopic characteristics of proliferative myositis and the possibility of its occurrence in the perioral soft tissues is important in avoiding misdiagnosis of this benign condition.

Cell Division

Lobular carcinoma of intraoral minor salivary gland origin. Report of twelve cases.

In an attempt to define more accurately the tumors grouped under the heading of "adenocarcinoma of salivary gland origin," we reviewed the cases in our registry that were classified as adenocarcinoma, carcinoma of salivary gland origin, and infiltrating epithelial salivary gland tumors. Eleven tumors that had certain unique microscopic features in common were identified. These eleven tumors and one that was reviewed in consultation make up the basis of this study. We classified these lesions as lobular carcinoma of salivary gland origin because of their remarkable microscopic resemblance to the breast tumors of the same name. These lesions appear to be of low-grade malignancy and have not recurred or metastasized in any of the eleven cases for which we have follow-up data, at times ranging from 5 to 80 months.

Adult

An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.

Four cases of an unusual skin eruption related to mandibular block injection are presented. The authors suggest an immunologic basis for the reaction, probably to the methylparaben preseravtive, and discuss a possible pathogenic mechanism. The medical-dental literature concerning untoward reactions to lidocaine is reviewed; particular attention is given alleged allergic reactions.

Arthus Reaction

Solitary intraoral keratoacanthoma. Report of a case.

The keratoacanthoma is a tumorlike proliferation which is rarely seen in the oral cavity. Both clinically and microscopically, it may bear close resemblance to squamous-cell carcinoma. The following article discusses the keratoacanthoma and, in addition, presents a case report of solitary intraoral keratoacanthoma.

Carcinoma, Papillary

Sialadenoma papilliferum.

Two previously unreported cases of sialadenoma papilliferum are presented. This brings the total number of reported cases of this entity to five. A review of the literature and a discussion of the histopathologic characteristics and possible histogenesis of the sialadenoma papilliferum are included.

Aged

The papillary cystadenoma of minor salivary gland origin.

This article reviews the literature of the papillary cystadenoma of minor salivary gland origin and discusses and attempts to clarify the true nature of these lesions. The criteria for diagnosis are presented, and classification of this lesion based on the Histological Typing of Salivary Gland Tumours (World Health Organization) is suggested. In addition, an interesting variant, which we have called the papillary cystadenoma, mucous-cell type, is presented.

Aged