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Biomedical subjects

H M Annis

Publications and source records attributed to H M Annis.

At least 19 recordsLinked to original sources

Measurement of antecedents to drug and alcohol use: psychometric properties of the Inventory of Drug-Taking Situations (IDTS).

The development, factor structure, and validity of the Inventory of Drug-Taking Situations (IDTS) is described. This 50-item self-report questionnaire, which is an extension of the Inventory of Drinking Situations (Annis, 1982. Inventory of drinking situations; Annis, Graham & Davis, 1987, Inventory of drinking situations (IDS): User's guide), is designed to assess the situational antecedents to use of a wide range of drugs of abuse. The IDTS consists of 8 subscales that measure a client's substance use in the 8 situations identified in the work of Marlatt (1978, Alcoholism: New directions in behavioral research and treatment): Unpleasant Emotions, Physical Discomfort, Pleasant Emotions, Testing Personal Control, Urges and Temptations to Use, Conflict with Others, Social Pressure to Use, and Pleasant Times with Others. Reliability, factor structure and validity of the IDTS were assessed on 699 clients admitted to the Addiction Research Foundation's treatment facility in Toronto. The IDTS was shown to have reliable subscales. The IDTS total score correlated with self-ratings of the severity of the clients' substance use problem, and with retrospective reports of frequency of use (drugs) and quantity of use (alcohol), years of usage, and severity of dependence. Confirmatory factor analysis was used to test the fit of the data to Marlatt's model of substance use situations, as well as to several alternative models. The goodness-of-fit indicators suggested that the best fit for the data was an 8-factor model corresponding to the 8 subscales based on the Marlatt categories. Evidence was presented that the 8 subscales can be further grouped into 3 second-order factors: (1) negative situations, (2) positive situations, and (3) temptation situations. The negative situation subscales of Unpleasant Emotions, Conflict with Others and Physical Discomfort were found to be correlated with the SCL-90R Depression scale. Interpersonal Sensitivity scale and Somatization scale respectively. The positive social situation subscales of Pleasant Times with Others and Social Pressure to Use were found to be negatively correlated with percentage of time using alone, and positively correlated with pressure from friends and family to use. On the States of Change Readiness and Treatment Eagerness Scales (SOCRATES), clients at the precontemplation stage of change had relatively flat, undifferentiated IDTS profiles (i.e. little scatter of subscale scores), whereas clients in the determination stage had the most differentiation in their IDTS subscale scores. Excellent comparability was found for alcohol clients between the IDS and the IDTS. Evidence was also presented for adequate comparability between the computer and paper and pencil administrative formats of the IDTS.

Adult↗

The role of coping in relapse crisis outcome: a prospective study of treated alcoholics.

This study investigates the influence of coping on the outcome of a relapse crisis for a sample of 125 treated alcoholics during the first 12 weeks following treatment completion. Both number and type of coping responses were examined. Results indicated that survival of a relapse crisis was most strongly related to the number of coping strategies used. Termination of a drinking episode was also related to number of coping responses. In addition, the type of coping strategy influenced survival, with the exclusive use of active coping strategies significantly associated with abstinence outcome compared with the exclusive use of avoidant strategies. Combining active and avoidant strategies appeared to be most effective for terminating a drinking episode. Results are discussed in the context of the cognitive-behavioral model of relapse, the general literature on coping behavior and the findings of other relapse studies.

Adaptation, Psychological↗

A controlled field trial of group versus individual cognitive-behavioural training for relapse prevention.

Results are presented of a randomized field trial comparing two aftercare regimes, namely individual versus group delivery of a structured relapse prevention approach. Two addictions treatment programs (one a 12-Step 26-day residential program, the other an evening group counselling program) implemented structured relapse prevention in either group or individual format as part of the first three months of aftercare. Process measures (e.g. attendance, client satisfaction) indicated that both group and individual formats were delivered very successfully at both sites. Follow-up rate at 12 months across both programs was 74%, and drinking and drug use at the 12-month follow-up was substantially less than use at entry into treatment. However, there were no significant differences in outcomes between individual and group delivery on any of the alcohol or drug use measures. Only one psychosocial outcome measure (social support from friends at 12-month follow-up) showed a significant difference for format and it favored the group format. These findings suggest some important directions for future research.

Adult↗

The use of calcium carbimide in relapse prevention counselling: results of a randomized controlled trial.

The effect of combining relapse prevention counselling with use of an alcohol-sensitizing drug was examined. Fifty-six alcoholic subjects who participated in a clinical trial of the short-acting alcohol sensitizing drug, citrated calcium carbimide, were randomly assigned to: (i) a Physician Advice condition in which subjects took the drug within a context designed to reinforce the medical management of their drinking problem; and (ii) a Relapse Prevention condition in which subjects were instructed to pair use of the drug with planned entry into high risk drinking situations and to gradually reduce reliance on the drug by developing alternative coping behaviour patterns. As predicted, subjects receiving carbimide in conjunction with relapse prevention counselling showed significant growth in internal attribution for change; whereas those receiving carbimide under more traditional medical management showed no movement toward internality. On measurement of alcohol consumption at 6, 12 and 18 months follow-up, there was some indication of superior maintenance of treatment gains at 18 months post-treatment for subjects who had received relapse prevention counselling, although the effect did not reach a conventional level of significance (F = 2.82; P less than 0.06). The findings are interpreted as consistent with a cognitive social-learning analysis of the maintenance of behaviour change.

Adult↗

A cognitive-social learning approach to relapse: pharmacotherapy and relapse prevention counselling.

A cognitive-social learning model of relapse prevention, specifically Albert Bandura's theory of self-efficacy, is one of the most influential theoretical frameworks that has been applied to the problem of relapse in the substance abuse field. Theory and research within this approach are reviewed and future directions for research are suggested. It is proposed that the critical distinction drawn between treatment strategies aimed at "initiation" versus "maintenance" of behaviour change provides a theoretical framework for the use of pharmacological agents in the treatment of alcohol problems. Pharmacological agents can be powerful in initiating a change in consumption, but if patients externally attribute to the drug the cause of their improvement, maintenance of improvement following withdrawal of the drug is likely to be poor. Relapse prevention counselling procedures, on the other hand, have been designed to provide self-attribution for change in drinking behaviour on the part of patients to promote maintenance of treatment effects. A combined approach using pharmacological agents (aimed at initiating a change in drinking) in conjunction with relapse prevention counselling procedures (aimed at fostering internal attribution and maintenance of change) should improve long-term outcome results. Available empirical evidence is presented.

Alcoholism↗

Outcome and efficacy expectancy in the prediction of post-treatment drinking behaviour.

A recent controversy in research on self-efficacy theory has been directed at the role of outcome and efficacy expectancies in the prediction of behaviour. While Bandura maintains that outcome expectancies add little information to prediction beyond that explained by efficacy expectations, others disagree. The present study explored the efficacy-outcome expectancy relationship in a population of alcoholic clients as they moved through a traditional treatment program and were contacted following a three-month aftercare period. Results indicated that outcome expectancies (defined as the costs and benefits expected to result from a change in drinking) did not predict consumption at follow-up. However, self-efficacy (defined as confidence in being able to resist the urge to drink heavily) assessed at intake of treatment, was strongly associated with the level of consumption on drinking occasions at follow-up. These findings are discussed in relation to the relevance of self-efficacy theory to research and treatment of alcoholic patients.

Adult↗

Calcium carbimide in alcoholism treatment. Part 2: Medical findings of a short-term, placebo-controlled, double-blind clinical trial.

Drug-induced toxicity in chronic alcoholics who participated in a 4-month placebo (Pl)--controlled clinical trial of the efficacy of calcium carbimide (CC) is reported. Daily monitoring of patients' compliance indicated that 85% of study medications were taken, and very little drinking took place during the study. Patients did not report more symptoms or experience more medical problems during CC administration than during placebo administration. There was no evidence of hepatotoxicity, or behavioural toxicity. Mean white blood cell count was slightly increased during CC treatment, and returned to baseline values when CC was stopped. Thyroid function was not affected by CC in patients with normal pretreatment function. However one patient with pretreatment reduced thyroid function became hypothyroid after CC administration, which indicates a need for systematic monitoring. We conclude that CC is safe for use in alcoholics with normal thyroid function, and may be the preferred alcohol-sensitizing drug in some situations.

Administration, Oral↗

Calcium carbimide in alcoholism treatment. Part 1: A placebo-controlled, double-blind clinical trial of short-term efficacy.

A randomized, double-blind, placebo-controlled single cross-over study of the alcohol sensitizing drug, calcium carbimide (CC), was conducted in 128 patients with alcohol dependence. Seventy-one (55%) completed the 4-month study. Patients reported drinking and pill-taking behaviour, and submitted urines (for analysis of alcohol and the tablet marker riboflavin) on 97%, and 91% of treatment days, respectively. All of the 69 analyzable completers were abstinent on at least 85% of days, and 58% (40) were alcohol-free during the study. Medications were taken on at least 85% of days. Symptoms and adverse clinical findings were not increased in frequency during CC, compared to placebo. Seventy-eight per cent of the patients believed they had received CC throughout the study, suggesting that CC exerts a strong psychological deterrent effect. Alcohol consumption was significantly reduced to the same extent with CC and placebo, compared to pre-treatment levels.

Adult↗

The reactive effects of follow-up assessment procedures: an experimental study.

A four group randomized control study designed to investigate the reactive effects of follow-up interviews and self-monitoring procedures on the self-reported drinking patterns of treated alcoholics failed to demonstrate any such effects. However, problems were experienced in gaining participation in frequent follow-up interviews and with the use of daily self-monitoring procedures. Limitations on the conclusions that can be drawn are discussed.

Adult↗

Maturational changes in Canadian adolescents' cognitive attitudinal structure concerning marijuana.

Thirty-four items concerning marijuana use were administered three times to a cohort of Canadian high school students between Grades 11 and 13, in 1977 (n = 439), 1978 (n = 419), and 1979 (n = 167). These items were designed to measure four distinct constructs: attitude, perceived peer approval or disapproval, concern about risks, and symbolic protest against conventional society. A cross-sectional factor analysis of the Grade 13 data supported the hypothesized factor structure, as had earlier work with college students. However, analogous analyses on the Grade 11 and Grade 12 data contradicted the hypothesized factor structure. Most notably, separate factors for positive and negative attitude appeared in the Grade 11 and 12 analyses. The data were interpreted primarily in terms of maturational changes, largely through elimination of alternative interpretations by internal analyses and previous findings. Implications were discussed for adolescent cognitive-attitudinal development, attitude theory, and analysis of panel data.

Adolescent↗

Discriminant analysis and the selection of patients for controlled drinking programs: a methodological note.

The criterion group classification scheme commonly used in conjunction with discriminant function analysis places individuals in the group for which their membership probability is the highest. This optimizes the proportion of correctly classified cases. The clinical utility of a discriminant based scheme may, however, be underestimated if the proportion of correctly classified cases is the only concern. For clinical purposes, attention must also be paid to minimizing serious diagnostic errors and to improving predictions for individuals. Clinicians can address these concerns by considering membership probabilities for each criterion group of interest. The utility of this approach is illustrated using data from a study in which discriminant analysis was used to identify the characteristics of problem drinkers who abstained, controlled their drinking, or continued to drink heavily after treatment.

Alcohol Drinking↗

Gamma-glutamyl transpeptidase and high-density lipoproteins cholesterol in male problem drinkers: advantages of a composite index for predicting alcohol consumption.

Forty male problem drinkers, participants of a treatment follow-up study, were assessed for levels of gamma-glutamyl transpeptidase (GGTP) and high-density lipoproteins cholesterol (HDL-C) in relationship to self-reported alcohol consumption over the previous 3-week period. A composite index of GGTP and HDL-C was superior to GGTP or HDL-C alone in discriminating abstinent/light, moderate, and heavy drinkers.

Adult↗

Self-report reliability of skid-row alcoholics.

The stability of self-report of 72 skid-row alcoholics over a one to six month interval was explored. Relatively high response agreement on reinterview was indicated for demographic items, but less reliability was observed on items assessing social functioning and drinking patterns. Implications of the findings for the evaluation of treatment programs are discussed.

Adult↗