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Biomedical subjects

H M Beumer

Publications and source records attributed to H M Beumer.

At least 37 records · Page 2Linked to original sources
PubMed1976

Objective evaluation of antitussive agents under clinical conditions.

A new method for objective assessment of cough under normal or pathological conditions is described. Thoracic coughing can be discriminated from any other pressure wave because of its relatively high frequency. This method was applied in a double blind crossover trial in 18 patients with respiratory disease.

Antitussive Agents↗
PubMed1975

Antagonism of fenoterol against beta-blocking drugs bunitrolol and practolol in asthmatics.

In 4 X 10 young white male histamine-sensitive asthmatics without bronchitis or emphysema, the antagonism of fenoterol (40 mug) to bunitrolol (2.5 and 5 mg) or practolol (20 and 30 mg) was tested in an open comparative trial. Pulse frequency and several physiological parameters were determined before and after histamine challenge test, after injection of beta-blocking drug and after injection of fenotrolol. All groups were found to be equally sensitive to histamine. Bunitrolol and practolol were found to have no influence on histamine effect. It was also found that bunitrolol in the dosages tested is a much more potent beta-blocking drug in the bronchi compared to practolol in the dosages tested were equivalent. beta-Blockade of practolol (20 or 30 mg) could completely be antagonized by 40 mug fenoterol; this dosage was not sufficient to antagonize 2.5 or 5 mg bunitrolol.

Adolescent↗