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Biomedical subjects

H M Goldman

Publications and source records attributed to H M Goldman.

At least 19 recordsLinked to original sources

An unusual cutaneous reaction secondary to allopurinol.

A 60-year-old man presented with erythematous papules and plaques on his body as well as a violaceous indurated nodule on his face. A cutaneous drug reaction secondary to allopurinol was considered. Examination of biopsy specimens revealed a dense lymphocytic infiltrate of the skin as is seen in lymphocytoma cutis. The lesions cleared promptly after use of allopurinol was discontinued. A literature review showed that an eruption of this kind, including a nodule on the face that histologically simulated a lymphocytic infiltrate of the skin, has not yet been reported secondary to allopurinol.

Allopurinol

Laterally repositioned "stimulated" osteoperiosteal pedicle grafts in the treatment of denuded roots. A preliminary report.

In order for successful coverage of denuded roots to be accomplished, correctly applied fundamental biological principles must be considered in the choice and utilization of the surgical modality. In this report some representative clinical cases are presented to indicate favorable results that may be achieved with stimulated osteoperiosteal pedicle flaps. These cases are part of an ongoing clinical and statistical evaluation.

Gingiva

The gingival autograft and gingivectomy.

A rationale and technique for the utilization of the combined procedures of the gingival autograft and the gingivectomy technics for the purpose of pocket elimination and creation of an adequate zone of attached gingiva has been presented. It allows for the predictable and relatively atraumatic treatment of gingival problems in which there has been no deformity of the underlying osseous structures.

Connective Tissue

A long term clinical study evaluating the effect of two dentifrices on oral tissues.

1. A long term (54 months) supervised, double-blind human clinical study has been conducted to ascertain whether the routine use of a commercially available cosmetic dentifrice, with purported stain removal and flavor impact characteristics, would cause adverse manifestations in the oral tissues, as compared to the similar use of a more conventional type of commercially available dentifrice. 2. One hundred and twenty male and female subjects (aged 12 to 70) were randomly assigned to the use of one of the two dentifrices under investigation, after which they used the assigned dentifrices twice daily (1 min each brushing) under supervised conditions for a period of 54 months. 3. Clinical examinations were conducted on all subjects initially (base line), and at 3-month intervals throughout the 54-month course of the study. This examination included a complete and thorough inspection of the oral soft and hard tissues. 4. The results after 54 months of continuous use of the dentifrices (representing a total dentifrice/oral tissues exposure time of approximately 45 hours per subject) indicated that neither of the two dentifrices caused any adverse reactions of the oral soft tissues and that both dentifrice groups had similar patterns and levels of cervical abrasion and/or erosion. 5. The results also indicate a lack of direct correlation between laboratory abrasivity values (as determined by a radioactive dentin abrasion procedure) and the clinical situation, thus suggesting that factors other than dentifrice abrasivity may play an important role with regard to tooth wear.

Adolescent

The role of the dental specialist in the hospital.

As can be seen from this incomplete list of dental specialties and functions they perform in the hospital, there is an increasing participation of dental specialists in the delivery of total health care to the hospitalized patient. In order to disseminate knowledge further of the special protocols of hospital practice and of special hospital dentistry problems, the American Association of Hospital Dentists was formed and publishes a journal containing this special information.

Dental Service, Hospital