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Biomedical subjects

H M Goldstein

Publications and source records attributed to H M Goldstein.

At least 19 recordsLinked to original sources

Abdominal pansonography in the evaluation of renal cancer.

Abdominal pansonography was performed in 34 patients after solid renal tumors were diagnosed. Included were evaluation of the inferior vena cava (IVC), the liver, and the retroperitoneal area. Additional findings including hepatic metastases, IVC extension of tumor, and retroperitoneal nodal masses were discovered in 14 patients. The role of pansonography as a noninvasive adjunctive diagnostic tool for more complete staging and treatment planning of renal cancer is discussed.

Adenocarcinoma

Comparison of scintigraphy, sonography, and computed tomography in the evaluation of hepatic neoplasms.

A comparison of scintigraphy, ultrasonography, and computed tomography (CT) in 94 proven patients with clinically suspected liver disease is reported. CT proved to be the most accurate in detecting masses and assessing the complete extent of intrahepatic disease. The most reliable combination was CT and scintigraphy. The specific advantages and disadvantages of each method are discussed. The diagnostic scheme followed in the imaging evaluation of an hepatic mass in our clinical practice is discussed.

False Negative Reactions

Radiologic demonstration of multiple foci of malignancy in the esophagus.

Three patients, each with two synchronous esophageal carcinomas demonstrated radiologically, are presented. The importance of complete esophageal evaluation in patients with one obvious tumor of the esophagus is emphasized. Assessment of the full extent of disease in such cases directly affects treatment planning.

Aged

Gray scale ultrasonography in the evaluation of metastatic melanoma.

One hundred and eight ultrasonographic examinations of the abdomen and pelvis in 89 patients with malignant melanoma were reviewed. Forty of these patients were found to have metastatic disease demonstrated by this new diagnostic modality. The varied ultrasonographic manifestations of melanoma are illustrated. Its use in staging and evaluating therapy is stressed.

Abdominal Neoplasms

Ultrasonic demonstration of inferior vena caval involvement with right adrenal gland masses.

Ultrasonographic findings in 13 right adrenal gland neoplasms were reviewed. Primary malignancy was the etiology in four patients and metastatic malignancy in nine. Anterior displacement and/or indentation of the posterior aspect of the inferior vena cava was present in nine patients. This sign, although nonspecific, helpful in the localization and diagnosis of right adrenal lesions.

Adolescent

Percutaneous transperitoneal aspiration biopsy of pancreatic masses.

Percutaneous fine-needle aspiration biopsy of pancreatic masses was performed in 34 patients. Biopsies were performed with a 22 or 23-gage, spinal-type needle under fluoroscopic guidance. Correct results were obtained in 73% of the patients including 21 patients with pancreatic carcinoma. No complications occurred. The primary indication for aspiration biopsy was to document the presence of malignancy and avoid a diagnostic laparotomy in patients considered to be unresectable.

Adolescent

Transcatheter therapy of gastrointestinal arterial bleeding.

Transcatheter therapy for arteriocapillary gastrointestinal bleeding is often an effective form of treatment. The choice of transcatheter therapy (ie, vasoconstrictor or occlusive) often is dependent on the etiology and location of bleeding. Vasopressin is a generally safe form of treatment which is often successful in treating bleeding secondary to gastritis, Mallory-Weiss mucosal tears, and diverticular disease. It is less effective in treating bleeding peptic ulcers, neoplastic bleeding, or bleeding when clotting abnormalities exist. Occlusive therapy is an effective alternate form of therapy in selected circumstances. Ischemic complications from vasoconstrictor and embolic therapy may occur and require appropriate caution and discretion with their use.

Aged

Computed tomography in the evaluation of musculoskeletal neoplasms.

In a study of 62 musculoskeletal neoplasms, computed tomography contributed little to establishing tissue diagnosis. Its primary value lay in the assessment of intraosseous and/or extraosseous extent of disease. CT also established the presence or absence of disease in a small number of cases with clinically questionable findings. In most cases, conventional radiographic methods were superior in diagnosing musculoskeletal neoplasms.

Adolescent

Ultrasonography of necrotic hepatic metastases.

Twelve patients with sonolucent hepatic metastases studied with gray scale ultrasonography are presented. Extensive necrosis presumably accounts for the sonolucent appearance of the hepatic lesions. The spectrum of ultrasonographic features and correlations, particularly with computed tomography, are presented. The similarity between anechoic hepatic metastases and benign conditions of the liver is emphasized.

Adult

Ultrasonography in the evaluation of post-nephrectomy renal cancer patients.

The role of ultrasonography in the evaluation of 12 patients who had previously undergone nephrectomy for renal carcinoma is discussed. Ultrasonography is a useful, noninvasive means of evaluating such patients for recurrence of disease. The ultrasonographic features of retroperitoneal recurrence and a potential diagnostic pitfall of bowel loops in the renal bed are emphasized.

Adult

Gray scale ultrasonography of adrenal neoplasms.

Ultrasonic characteristics of 21 adrenal neoplasms (19 patients) examined by gray scale ultrasonography are reviewed. The significance of the adrenal-renal cleavage plane is discussed. In our experience the cleavage plane only has definite localization value when it separates the adrenal gland from the kidney on all ultrasonographic sections. Compression of the posterior wall and/or anterior displacement of the inferior vena cava was seen in about two-thirds of the right adrenal tumors. The difficulty in examining left adrenal masses is emphasized. Ultrasonography has proved to be an excellent screening procedure for adrenal tumors.

Adenocarcinoma

Gray scale ultrasonographic evaluation of hepatic cystic disease.

Eight patients with various forms of hepatic cystic disease studied with gray scale ultrasonography are described. Four had solitary cysts, two had multiple simple liver cysts, and two had congenital polycystic liver and kidney disease. The spectrum of ultrasonographic features in benign cystic disease of the liver is discussed. All eight patients were felt to have malignant disease in the liver prior to ultrasonographic evaluation. The value of gray scale ultrasound as a noninvasive means of differentiating cystic disease from suspected metastatic disease is emphasized.

Adult

Ultrasonic detection of renal tumor extension into the inferior vena cava.

Five cases of extension of renal carcinoma into the inferior vena cava were detected using gray scale ultrasonography. Two different ultrasonographic appearances reflecting the intracaval tumor were observed. Four patients had one or two intraluminal echogenic nodules or thrombi, and the fifth case manifested generalized caval dilatation with innumerable diffuse low amplitude echoes emanating from the lumen. The role of ultrasonography in the complete evaluation of the patient with renal carcinoma is discussed, and the ultrasonographic features of intracaval tumor are demonstrated.

Adolescent

Prone view ultrasonography for pancreatic tail neoplasms.

Ultrasonography was performed in the prone and supine positions in six patients with neoplasms in the tail of the pancreas. The masses were either not apparent (three cases) or less well visualized on the supine scans. The value and indications of the prone position in the ultrasonic evaluation of masses in this portion of the pancreas are documented. Prone scanning is particularly useful when malignant ascites interferes with pancreatic visualization in the supine position.

Adult

Computed tomography of necrotic hepatic metastases.

Seven patients with necrotic liver metastases were evaluated by computed tomography. The metastases demonstrated low attenuation areas varying from a small central portion to the entire lesion. Other findings included mural nodules and fluid-fluid levels. Possible etiologies for necrotic metastases are presented and their differential diagnosis is discussed.

Adult