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Biomedical subjects

H M Hsu

Publications and source records attributed to H M Hsu.

21 records · Page 2Linked to original sources
PubMed1989

Seroepidemiology of toxoplasmosis on Taiwan and some of the offshore islands.

Over 4,000 serum specimens from various population groups on Taiwan, Lan Yu, and the Pescadores Islands were tested for antibodies to Toxoplasma gondii by use of the indirect hemagglutination test. Only 74 sera were considered to be positive at titers of 1:256 or greater. The highest prevalence rates of positive antibody titers were obtained from 335 people from Ian Yu Island; 59 (18%) were considered positive. A few (11 soldiers) positive titers were detected in sera from 2,487 Chinese Marine recruits on first bleedings and 4 found positive on a second bleeding 12-18 months later. Only a few suspected cases of toxoplasmosis have been reported from humans, yet a number of animals have been found infected with the parasite and other animals found serologically positive. These and other aspects of toxoplasmosis on Taiwan are discussed.

Antibodies, Protozoan↗
PubMed1988

Efficacy of a mass hepatitis B vaccination program in Taiwan. Studies on 3464 infants of hepatitis B surface antigen-carrier mothers.

To evaluate the efficacy of the mass hepatitis B vaccination program in Taiwan in interrupting perinatal hepatitis B virus transmission, 3464 randomly selected 18-month-old infant vaccinees born to hepatitis B surface antigen-carrier mothers were recruited from 9697 eligible infants during a six-month period of the program. They were divided into ten groups according to maternal infectivity and compliance with the vaccination schedule. Serum samples were tested for hepatitis B surface antigen, antibody to hepatitis B surface antigen, and antibody to hepatitis B core antigen. In 786 infants who had highly infectious mothers and who received hepatitis B immune globulin and vaccine on schedule, the protective efficacy was about 85%. The efficacy seemed to be slightly lower in those immunized off schedule. Overall, 11% of infants still carried hepatitis B surface antigen, and 81% of the infants had antibody to hepatitis B surface antigen that exceeded 10 mIU/mL in more than 90% of them. The geometric mean titers of antibody to hepatitis B surface antigen were more than 200 mIU/mL in every group of infants. We conclude that the mass vaccination program is efficacious in preventing perinatal hepatitis B virus transmission and the chronic carrier state; most infant vaccinees have adequate levels of protective antibody at 18 months of age. This program is extremely significant in the control of hepatitis B virus infection in Taiwan.

Carrier State↗