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Biomedical subjects

H M Lai

Publications and source records attributed to H M Lai.

10 recordsLinked to original sources

Pseudotumour cerebri associated with arteriovenous malformations.

The association of intracranial hypertension and arteriovenous malformations is described in two patients. Both patients had the typical clinical features of pseudotumour cerebri and were found to have intracranial arteriovenous malformations on arteriography. The mechanism of raised intracranial pressure in patients with arteriovenous malformations is discussed.

Adult

Use of NMR and MRI to study water relations in foods.

Water is the most important component of a food system, because it influences so many process variables, product characteristics, and stability attributes. Some of the most successful techniques used to probe the behavior of water in food systems are Nuclear Magnetic Resonance (NMR) spectroscopy and, more recently, pulsed-field gradient NMR and Magnetic Resonance Imaging (MRI). The purpose of this chapter is to review the theory underlying these techniques and to present several examples of how they have been applied to study water relations in foods.

Carbohydrates

Is sick sinus syndrome an adenosine-mediated disease? Effects of intravenous aminophylline on sick sinus node function after pharmacologic autonomic blockade.

To assess the effects of intravenous aminophylline on the sinus node, 12 patients with clinical and Holter monitor-documented sick sinus syndrome were studied (1) during the control state, (2) after pharmacologic autonomic blockade and (3) 5 min after intravenous administration of aminophylline. The effects of aminophylline on sinus node function were compared with those after pharmacologic autonomic blockade. No significant improvement of sinus node function was found after intravenous aminophylline administration with a mean sinus cycle length and a mean maximum CSRT of 968 +/- 218 and 1832 +/- 1036 ms, respectively. The mean serum theophylline level was 10.9 +/- 1.7 micrograms/ml. Since aminophylline is an adenosine receptor antagonist, these findings suggest that intrinsic adenosine may not play an important role in pathogenesis in patients with chronic and advanced sick sinus syndrome.

Adenosine