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Biomedical subjects

H M Magalhães

Publications and source records attributed to H M Magalhães.

17 recordsLinked to original sources
PubMed2004

Renal failure as a determinant of mortality after cardiac transplantation.

INTRODUCTION: Patients with heart failure frequently develop renal failure, which increases the mortality rate among patients undergoing cardiac transplantation. PURPOSE: To determine whether preoperative renal function influenced postoperative mortality in cardiac transplantation recipients. MATERIALS AND METHODS: The measurements of plasma urea, plasma creatinine, and 24-hour creatinine clearance in patients who underwent cardiac transplantation were correlated with mortality at 30, 90, and 365 days after the procedure, using Student t test for continuous variables and the chi-square test for categorical variables. RESULTS: All variables correlated with mortality, particularly plasma creatinine at 30, 90, and 365 days (P =.029,.003, and.0029, respectively). CONCLUSION: Preoperative renal failure is a mortality indicator in cardiac transplantation recipients.

Female↗
PubMed1994

[Infective endocarditis in children and adolescents].

PURPOSE: To assess infective endocarditis (IE) predisposing factors, etiologic agents and hospital course in infants and adolescents. METHODS: We Studied 222 patients admitted under compatible IE diagnosis, from 1985 to 1990. The population of this study is fifty patients (23%) under 16 years of age. RESULTS: Rheumatic valvular disease, as predisposing cardiopathy was proeminent within 9 to 16 years of age, markedly Statistical difference when compared to age range of 0 to 8 years (p < 0.05). Among congenital cardiopathies, the most frequent were: interventricular septal defect (26.0%) and tetralogy of Fallot (21.7%). Blood cultures, surgical material or emboli cultures were positive in 35 (70.0%) assessed patients. Streptococcus viridans (45.7%) and Staphylococcus aureus (42.8%) were the etiologic agents most often isolated. It was found that endocarditis by Staphylococcus aureus had mortality rate of 53.3% [(clinical (66.6%) and surgical (44.4%)], (p < 0.05) when compared to those by Streptococcus viridans; with total mortality of 6.2% (no clinical death and 16.6% in the surgical group). Total in-hospital mortality (clinical and surgical) was 26.0% (13 deaths). CONCLUSION: IE in infants and adolescents in this studied population presented Streptococcus viridans responsible for 46.7% of patients with endocarditis and the Staphylococcus aureus for 42.8% were the etiologic agents most often found. Total, clinical and surgical mortality was greater in patients with endocarditis by Staphylococcus aureus when compared with those by Streptococcus viridans. Among the congenital cardiopathies, whether operated on or not, ventricular septal defect and of Fallot's tetralogy were the most involved ones; rheumatic cardiopathy Still remains a significant predisposing factor to infective IE in our country.

Adolescent↗
PubMed1994

[Myocardial infarction in infective endocarditis].

Two patients with chronic valvular heart disease and myocardial infarction were assisted at our hospital. Both of them were febrile and only one had petechiae associated with signs of valvular involvement led to suspicion of infective endocarditis. Although blood cultures were negative, echocardiographic, surgical and anatomopathologic findings were compatible with infective endocarditis. They required cardiac surgery during the acute phase of the infection because they presented progressive hemodynamic deterioration and no satisfactory response to antimicrobial regimen too. One patient died at late follow-up (two weeks after the hospital discharge) and the other survived, but with signs of cardiac failure (class II of NYHA) one year after the procedure.

Adolescent↗
PubMed1994

[Radiologic signal of dehiscence of Starr-Edwards aortic prosthesis].

A male 54 years-old patient with infective endocarditis through Staphylococcus aureus with prosthesis of Starr-Edwards aortic with clinical and echocardiographic signs compatible with dysfunction classified as severe. The x-ray images presented double silhouette of the prosthesis, thus suggesting its partial dehiscence. This case report points out that the detailed analysis of the X-ray may supply relevant data for the diagnosis of one of this complication thus influencing on management and prognosis.

Aortic Valve↗
PubMed1994

[Infective endocarditis in patients with permanent pacemaker].

Five patients who had permanent pacemaker and infective endocarditis were analyzed. Diagnose was confirmed by a positive blood cultures in all patients and 2 of them had identifiable vegetation in the echocardiogram too. The etiologic agent was Staphylococcus aureus in 3, Staphylococcus epidermidis in 1 and Staphylococcus viridans in 1. Three patients were treated with antibiotics alone: one had no clinical conditions to be operated, one died before surgery and one had good response to antimicrobial therapy alone. Two patients were submitted to antibiotic therapy and surgical removal of the pacemaker system, without complications. It was concluded that the surgical removal of the pacemaker system, as soon as possible, is the choice's therapy.

Adult↗
PubMed1980

[Myocardiopathies].

Explore the source record for details and available documents.

Cardiomyopathies↗
PubMed1979

Neonatal androgen effects on conditioned emotional response extinction of adult rats under various hormonal regimens.

Intact male rats and spayed female rats received 0.5 mg testosterone propionate in the first 24 hours after birth. They were divided into different groups, administered peanut oil, progesterone, oestradiol benzoate and testosterone propionate in adulthood. The animals were conditioned to fear with a shock paired sound. The experimental test consisted of investigating the conditioned emotional response (CER) extinction. It was verified that as to conditioned emotional response extinction, neonatally androgenized males were different from control males; neonatally androgenized females, testosterone propionate treated in adulthood were also different from control females. There was no significant difference between neonatally androgenized females oestradiol benzoate treated in adulthood and their control group. In comparing neonatally androgenized females having different hormonal treatment in adulthood, we verified that testosterone propionate treated females were significantly different from those treated with progesterone. On the other hand, neonatally androgenized females treated with oestradiol benzoate in adulthood were different from those that have had the same hormonal manipulation in neonatal period, but that were injected with progesterone in adulthood. It was concluded that conditioned emotional response extinction is facilitated by neonatal androgenization in non-oestrogenized male and female rats.

Age Factors↗
PubMedDate not supplied

[Information-related changes in attitude to mucocutaneous leishmaniasis of a population from an endemic region of the south of Bahia].

The mutilant nature of the mucosal form of leishmaniasis can cause alterations in personal relations. To identify the level of understanding of leishmaniasis and the psychological reaction to it patients and houseowners in an endemic area of Bahia were interviewed. Several false beliefs were identified and there was a strong tendency to reject mutilated patients among the population for a false fear of contagion. Possibly future clarification of the real nature of leishmaniasis could change such a negative attitude among the resident population.

Brazil↗