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Biomedical subjects

H M Utidjian

Publications and source records attributed to H M Utidjian.

At least 19 recordsLinked to original sources
PubMed1989

Mortality patterns among workers exposed to acrylamide.

A cohort of 8854 men, 2293 of whom were exposed to acrylamide, was examined from 1925 to 1983 for mortality. This cohort consisted of four plant populations in two countries: the United States and The Netherlands. No statistically significant excess of all-cause or cause-specific mortality was found among acrylamide workers. Analysis by acrylamide exposure levels showed no trend of increased risk of mortality from several cancer sites. These results do not support the hypothesis that acrylamide is a human carcinogen.

Acrylamide↗
PubMed1989

Mortality patterns among employees exposed to acrylonitrile.

A cohort of 2671 men, 1774 of whom were exposed to acrylonitrile, was observed from 1951 through 1983 for mortality. No statistically significant excess of all-cause or cause-specific mortality was observed. Analysis of exposure duration to acrylonitrile with respiratory cancer mortality showed no trend. Men exposed to high levels of acrylonitrile had respiratory cancer rates similar to men not exposed in the workplace and to the US general male population. These study results do not support the hypothesis that acrylonitrile is a human carcinogen.

Acrylonitrile↗
PubMed1989

Mortality patterns among men exposed to methyl methacrylate.

A cohort of 2,671 men, 1561 of whom were exposed to methyl methacrylate, was observed from 1951 to 1983 for mortality. This cohort consisted of men from two plants. This study utilizes detailed exposure estimates and smoking status to evaluate mortality patterns. We find no statistically significant excess all-cause or cause-specific mortality. Analysis of dose of methyl methacrylate with several cancer sites showed no trend. Men exposed to high levels of methyl methacrylate had cancer rates similar to those for men not exposed in the workplace, as well as for other men in the US population. An earlier epidemiology study reported a significant excess of colorectal cancer among persons exposed to several substances including methyl methacrylate. Our study results and results from animal studies do not support the hypothesis that methyl methacrylate is a human carcinogen.

Adult↗
PubMed1979

Retrospective evaluation of reproductive performance of workers exposed to ethylene dibromide (EDB).

An attempt has been made to examine retrospectively any antifertility influence of ethylene dibromide (EDB) by studying the reproductive performance of men exposed to EDB, exclusively on the basis of their reproductive histories in terms of live births to their wives, subsequent to their occupational exposure to EDB. The number of live, putatively legitimate, natural children born to the wives was compared to the expected number derived from national fertility tables published for successive birth cohorts of U.S. women by the National Center for Health Statistics. The indirect standardization method was used to adjust for the confounding effects of maternal age, parity, race and calendar year in deriving the expected births. The number of observed births was expressed as a percentage of the expected in assessing the workers' reproductive performance. One of the four plants studied showed a significant decrease in fertility.

Adult↗