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Biomedical subjects

H Massé

Publications and source records attributed to H Massé.

14 recordsLinked to original sources
PubMed1987

[Mortality and morbidity due to alcoholism].

The basic data used are statistics of causes of death, with correction taking into account unspecified causes of death. In a first part, we show different aspects of mortality due to alcoholism and cirrhosis of liver: variations recording sex and age group, time evolution, seasonal variations, regional variations. In a second part, we estimated, with a model, prevalence and incidence rates of these two causes of death, according sex and age group.

Adolescent↗
PubMed1987

[Alcoholism and risk factors].

The basic data used are: statistics of causes of death by sex for the 45-64 years age group, 17 socio-demographic factors, blood groups and overweight. In a first part, we measure the statistical linkage between mortality by alcoholism and cirrhosis of liver and socio-demographic and biometric factors. In a second part, we show the weight of alcoholism as risk factor in the mortality by cause, the linkage between alcohol consumption and cancers, the weight of alcoholism in an health index.

Alcohol Drinking↗
PubMed1987

[Alcohol consumption].

The basic data used are statistics of causes of death due to alcoholism by sex and age group. In a first part, we estimated, with some simple hypotheses, alcohol consumption according sex and age group. In a second part, we show the existence of two kinds of consumption: endogenous or innate, exogenous or acquired. Finally, in a third part, we measure the linkage between alcohol and general and endogenous consumption.

Adolescent↗
PubMed1987

[Alcoholism and mortality by cause, alcoholism and tobacco].

The basic data used are statistics of causes of death by sex and age group, with corrections taking into account unspecified causes of death. In a first part, we measure, with a model, the statistical linkage between mortality by cause and alcohol consumption, estimated from mortality of alcoholism. In a second part, the linkage has been calculated without influence of tobacco consumption.

Adolescent↗
PubMed1983

Evaluation of morbidity from mortality.

The authors have attempted to measure morbidity involved in mortality, from French regional statistics of causes of death, for the 1968-1970 period. Particularly, they have estimated prevalence rates (proportion of patients at a given moment) and incidence rates (annual proportion of new patients). These rates have been assessed by sex, and for age groups: 15-44 years, 45-64 years, 65-74 years, 75 years and more, and for 18 leading causes of death, according to the International Classification of Diseases (1965). Statistics of causes of deaths have been corrected to take into account non specified causes of death.

Adolescent↗
PubMed1979

Action of psychoactive drugs on sex-related differences of OF1 mice; intraspecific aggressiveness and acute hypoxia survival.

The purpose of this study was to examine (1) whether there were a relationship between the sex-related differences in 51-day-old OF1 mice, regarding male aggressiveness and their sensitivity to an acute hypoxic (nitrogen) 50% lethal challenge, and (2) whether these sex-related differences could be modified by psychoactive drugs acutely injected at nonincapacitating doses. The introduction of a previously isolated male in grouped (10) mice decreased survival to the hypoxic challenge more in females than in males. The previously isolated male, which acted as an 'aggressor' with grouped mice (fights and flights in male groups, and mounts in female groups), had a higher hypoxic mortality than the mice of the groups under aggression. Psychoactive drugs were intraperitoneally injected in grouped mice before the introduction of the male aggressor. Clorazepate (5 and 25 mg/kg) abolished the sex-related difference in hypoxic survival in groups in the presence of, but not in the absence of, the previously isolated male. Conversely, hydroxyzine (5 mg/kg) and dexamphetamine (1 mg/kg) suppressed the sex-related difference only in the absence of the aggressor. The effects of these drugs appeared to be associated more with flight than with fight reactions provoked by the introduction of the male aggressor. A deep hypothermia was noted in clorazepate-treated mice at the issue of the hypoxic challenge.

Aggression↗
PubMed1978

[Aggression toward groups of male and female OF1 mice by a male congenere and survival to acute hypoxia].

In OF1 mice, a 107 day-old mouse, isolated since 51 days, acts as an "aggressor" when introduced into a group of 10 males or into a group of 10 females of the age of 51 days. This results in fights and flights in the males' group and in copulations in the females' group. In 31 experiments, each performed on a total of 40 males and 40 females, it was observed that an acute DL50 hypoxia (inhalation of nitrogen) provokes a mortality significantly (p less than 0.001) higher in the male "aggressors" (95.16%) than in the groups of 10 aggressed mice (mortality: 64.26% for the males' groups and 52.65% for the females groups). Besides, compared to control groups without male "aggressor", the introduction of the male congener significantly (p less than 0.001) increases the acute hypoxic mortality in the females' but not in the males' groups.

Acute Disease↗
PubMed1978

Hypoxia survival variations in male and female mice as functions of chronological and environmental factors.

The inhalation by mice for 20 min of 5.5% oxygen in nitrogen, performed 29 times over 40 months, causes a mortality of 49.81%. Correlation coefficients were calculated between hypoxia mortality and different parameters: environmental--lighting, temperature, hygrometry, barometric pressure, biological--sex, age, body weight; and chronological--circadian, circannual, pluriannual. Partial correlation coefficients eliminate several interrelationships and finally point out the statistical significance of transfer from dark to light (p less than 0.001), of circadian (p less than 0.05), and of circannual (p less than 0.01) hypoxic mortality variations. Moreover, a significant (p less than 0.001) sex-related difference of mortality (males: 56.94%; females : 41.14%) was observed, independently of the environmental and chronological parameters studied.

Age Factors↗
PubMed1977

[Sexual cycle period and resistance of mice to acute experimental hypoxia].

Variations of survival to an acute hypoxia (nitrogen) were studied, in 200 females, OF1, SPF mice, 72 days old, in groups of 10, at different periods of their estrus cycle, which were evidenced by vaginal smears. In mice which were in diestrus since 3-4 following days, the hypoxic survival (27.27%) was statistically less than in mice which were in estrus (58.00 %) or at the beginning of the diestrus (53.85 %).

Animals↗