[Experimental studies in humans on the synergistic action of prednisolone and phenylbutazone].
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Biomedical subjects
Publications and source records attributed to H Mathies.
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This paper is the result of a symposium that addressed the problem of disablement and social pension for patients with psychosomatic-rheumatological complaints. This especially concerns patients suffering from psychosomatic manifestation at the locomotor apparatus, who are increasingly disabled and necessitating a pension, without actual somatic findings justifying a vocational disablement. Primarily it is a clinical picture of a generalized tendomyopathy, often underestimated in its importance. Definitions, causes, and clinical pictures are presented. A critical phase decisive for the disablement, the personality of the would-be pensioner, considerations for the physician regarding diagnostic and therapeutic efforts, elements of time and environment, and conditions at the work-place are discussed. In some cases a pension will be unavoidable and justifiable, even if the somatic findings seem not to be sufficient. The psychogenic picture must be carefully determined differentiated from simulation; determining the cause of aggravation is essential.
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It is shown that the concept of "seronegative HLA B 27 associated spondarthritis," which is unsatisfactory even as a name, cannot be accepted as a new overgroup in a logically constructed classification. HLA B 27 occurs in certain of these illnesses almost inevitably as a predisposing antigen; in others it is merely a factor modifying the pattern of disease. The illnesses thus are obviously different. In any case, the concept itself is not a diagnosis, in spite of the fact that it is at present often employed as a diagnostic term.
The author describes the information gained from anamnesis which points to a psychogenetic cause of rheumatic complaints. These symptoms are part of the diagnostically important criteria which must be supplemented still further by means of a personal discussion with the patient. A great deal depends on the skill of the physician in conducting these talks, with regard to obtaining relevant information on personal problems which may be underlying the disease patterns. Of course the possibility of a connection of the detected problems with the clinical picture should be given.