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Biomedical subjects

H Meythaler

Publications and source records attributed to H Meythaler.

15 recordsLinked to original sources
PubMed1979

[Clinical experiences with timolol eye drops].

Three groups of chronic simple glaucoma (group I: newly adjusted patients; group II: previously satisfactorily pressure-regulated patients; group III: previously notsatisfactorily pressure-regulated patients) received treatment with Timolol eye drops for 4 months. In 34 eyes the intra-ocular pressure could be lowered below 22 mm Hg by Timolol alone, whereas 10 eyes additionally had to be treated with 1% epinephrine. The higher the initial pressure effect, the more pronounced the pressure-lowering properties of Timolol became. Especially in the first 2 weeks, less in the following 14 weeks, Timolol showed a loss in effectiveness. The application of Timolol instead of carbonic anhydrase inhibitors with acute angle-closure glaucoma and secondary glaucoma was successful. Timolol eye drops were tolerated very well. There were no local or systemic side effects.

Adult↗
PubMed1979

[Tumor metastases of the choroid: clinical picture and histology (author's transl)].

This paper is based on 21 patients with metastases of the choroid from extraocular tumors, observed over a period of 25 years (1952--1977) at Erlangen University Eye Clinic. Approximately 70% of these relatively rare metastases of the choroid are caused by cancer of the breast. Ophthalmoscopically, they are usually localized to the left of the posterior pole and are yellowish. In about 20% of the cases both eyes are affected. Since breast cancer is the most frequent cause of the primary tumor, women in the 40 to 60 age group are the most common sufferers. On the other hand, it is worth mentioning that in 2 cases the metastases were the first signs of any type of malignancy. Typical is the relatively flat, shell-like growth. In cytological specimens the portion of the retina covering the tumor normally shows no evidence of cystic degenerative change, in contrast to malignant melanoma. In view of the short average life expectancy of about 9 months, therapy should consist in preserving the eye and thus some degree of vision. Radiotherapy, chemotherapy or cytostatic therapy whould be tried. Enucleation is only indicated where there is severe pain, secondary glaucoma, amaurosis or if it is impossible to differentiate from a malignant melanoma.

Adenocarcinoma↗
PubMed1978

[Amaurosis fugax in obliterations of the carotid artery].

Lesions at the carotid bifurcation frequently cause transient cerebral ischemia and especially visual disturbances by microembolization. An early diagnosis is vital in order to prevent definitive blindness. Transient monocular blindness is an early diagnostic sign of ulcerated atheroma of the extracranial carotid artery. Symptomatology, diagnosis and therapeutic aspects are discussed.

Blindness↗
PubMed1978

[Amaurosis fugax and obliteration of the carotid artery (author's transl)].

Obliterative processes of the carotid bifurcation can be a starting point for cerebral and especially retinal microemboli. Early diagnosis is essential in protecting such patients from a definitive insult, or a reduction of sight which can go as far as permanent blindness, whereas the amaurosis fugax being the most common ocular symptom of the internal carotid insufficiency. Due to the fact ca. 65%--75% of the patients with ocular symptoms of a carotid insufficiency show forms of amaurosis fugax or photopical sensations, this symptom complex, especially in combination with temporary contralateral hemiparalysis, has to be evaluated as a classical symptom of carotid stenosis until the contrary can be angiographically proven. Only during the last few years has it become apparent that these microemboli originate from ulcerous or verrucous beds of the carotid bifurcation. The discovery of the above connections was only made possible through the improvements in carotid angiography technique.

Aged↗
PubMed1977

[Electron-microscopic findings in Bowen's disease of the conjunctiva (author's transl)].

The conjunctival tumors of eleven patients were histologically diagnosed as an intraepithelial squamous cell carcinoma Bowen's disease. All characteristic intraepithelial changes were manifest. Microinvasion, secondary dyskeratosia, dyskeratotic keratinisation, individual cell keratinization, and loss of intercellular desmosomes were clearly evident in the electron microscope. Virus-like organisms were not observed.

Aged↗
PubMed1976

[Alport-syndrom with participation of the cornea and alterations of ERG (author's transl)].

A description of a 26-year-old patient who had hearing difficulties, progressive nephropathy, and conus of the lens in both eyes is given. The ERG was below normal and the EOG remained normal. About the same time the nephropathy affliction occurred, a ringed abscess appeared in the left eye. Afterwards it healed with a scar, but half a year later the same affliction appeared in the right eye.

Adult↗
PubMed1976

[Eye involvement in plasmocytoma (author's transl)].

A description is given of a 37-year-old man, who suffered from a IgG myelom, diagnosed by internal medicine. The initial symptoms of the disease were grey-white, crystalline deposits in the cornea and recurring inflammation of the iris in both eyes. Only when a multiple recurring exophthalmos occurred, could the diagnosis be determined through an intensive internal examination. The continuing disease was still complicated by an insufficiency of the kidneys with hypertony and beginning retinopathia angiospastica.

Adult↗
PubMed1975

[Ocular findings in syndroma of Schimmelpenning-Feuerstein and Mims (author's transl)].

This is a description of a male patient, now 8-years-old, with the syndrome described by Schimmelpennig-Feuerstein and Mims. Characteristic for this clinical picture, which is classified as a phacomatosis, are a striated and sponge-like naevus sebaceus, disorders of the central nervous system taking the form of debility and epileptic attacks, and multiple anomalies of the eyes, such as microphthalmus, coloboma of the eyelids and optic nerve with ablatio falciformis, as well as dermoids and teratomas of the conjunctiva.

Child↗