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Biomedical subjects

H Milbradt

Publications and source records attributed to H Milbradt.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Percutaneous drainage of abscesses after stomach surgery].

Fifteen abscesses following various types of gastric surgery in 14 patients were treated by three different methods: 1. Multiple puncture under sonographic control, with complete drainage of the abscess. 2. The introduction of a catheter. 3. In the presence of a fistula, introduction of a catheter into the abscess through the fistula. Amongst the 14 patients, one had to undergo further surgery because of intestinal bleeding. In the other patients, there was complete healing without any complications or further surgery.

Abscess↗
PubMed1989

[Ultrasonic anatomy and study technic of the normal carpal tunnel and the distal median nerve].

The wrists of 16 normal volunteers were examined via high-resolution sonography with special reference to the carpal tunnel. In all cases the surfaces of the carpal bones, the flexor retinaculum, the tendons, the vessels, (Aa. radialis and ulnaris) and the nerves (Nn. medianus and ulnaris) were observed. The sonographic characteristics of the median nerve are discussed and the possibilities of identification are demonstrated. It appears that the echogenicity of the nerve depends strongly on the angle of the ultrasound beam.

Adult↗
PubMed1989

[In situ hybridization in detecting virus infections in biopsies following orthotopic liver transplantation].

Using the in-situ DNA hybridization we studied 62 liver biopsies from 34 patients for the presence of CMV-, EBV-, HBV-, and HSV-Genome. In the first biopsies positivity-rates were as follows: CMV 62%, EBV 71%, HBV 15%, HSV 15%. In 6 cases a conversion from a negative intranuclear CMV-status to a positive status was seen correlating with an increase in serological titers and with clinical signs of viral infection.

Adolescent↗
PubMed1989

[Ultrasound sonography in the diagnosis and follow-up of Achilles tendon rupture].

In addition to allowing definite diagnosis of Achilles tendon rupture and localization of the rupture site, ultrasonography also enables the examiner to grade the rupture and the course of healing for quantity and quality. Twenty patients with subcutaneous achilles tendon rupture were examined in a prospective study that is still in progress. In this trial an operative and a conservative-functional treatment with a newly developed shoe were compared. The dynamic examination revealed adaptation of the tendon in plantar flexion in two-thirds of the patients. After 2 weeks continuity of the tendon was restored in all patients. A remarkable increase in the regeneration of the tendon at the rupture or suture site was observed from the 4th to the 12th week. The variations in tendon structure were assessed, and a classification is presented.

Achilles Tendon↗
PubMed1989

[Sonographic diagnosis and differential diagnosis of neck cysts].

We report 101 patients with the clinical diagnosis of a branchial cyst investigated by ultrasonography. In 78 cases the diagnosis of a branchial cyst was confirmed by the ultrasound findings. The picture of a typical cyst was found in 26 cases, whereas a complex cyst filled with sludge or debris was found in 52 patients. Histology revealed a different diagnosis in 7 cases of ultrasonic complex cysts. Of 23 patients where a branchial cyst was excluded by ultrasound, histology showed a lesion other than a branchial cyst in 19 cases. In total, only 34.6% of the histologically confirmed branchial cysts displayed the typical signs of such a cyst on ultrasonography. However, in 91% of the patients with an actual branchial cyst we were able to confirm the diagnosis by ultrasound before operation. The differential diagnosis of other benign and malignant lesions of the neck resembling branchial cysts is discussed with examples.

Branchioma↗
PubMed1989

[Management of sonography in blunt abdominal trauma].

A standardized management of sonography in blunt abdominal trauma has replaced peritoneal lavage in our department. The sonographic evaluation is performed simultaneously with additional diagnostic and therapeutic procedures in the emergency room. The primary goal is the exclusion of intraabdominal bleeding. The management and the results of the diagnostic procedure are presented with reference to a consecutive series of 314 patients with blunt abdominal trauma or polytrauma. In 71 patients, laparotomy was performed because the sonographic findings were felt to indicate it. Only in two cases was the sonographic assessment incorrect (false-positive). Frequent sonographic and clinical controls are required especially when sonography cannot totally exclude intraabdominal bleeding during the initial assessment. If any discrepancies between negative or uncertain sonographic and suspect clinical findings remain, further high-tech diagnostic methods or exploratory laparotomy become necessary.

Abdominal Injuries↗
PubMed1989

Intravenous DSA and dynamic computed tomography for postoperative follow-up of type A aortic dissections.

We undertook a direct comparison of intravenous digital subtraction angiography and dynamic computed tomography in a follow-up study on 37 patients who had undergone surgery on the thoracic aorta for acute or chronic type A dissections. These are minimally invasive and complementary procedures: IV-DSA provides a clear angiographic image of the dissection, with visualization of the true and false channels, their distal extension and the supra-aortic and abdominal vessels they supply. Dynamic CT best demonstrates the proximal extension of the disease; it visualizes clotting in the false lumen and permits a more accurate measurement of the aortic width, and thus early recognition of a developing aneurysm.

Adult↗
PubMed1988

[Chylous lymphocele: a rare complication after gastrectomy for primary non-Hodgkin's lymphoma of the stomach].

Gastrectomy and extensive lymphatic resection were performed in a 55-year-old woman with primary non-Hodgkin lymphoma of the stomach. Three months later a large perihepatic lymphocele developed. After placement of a catheter under ultrasound control and evacuation of about 5.31 of chylous fluid there was no recurrence or further sequelae. This complication is so rare that it should not be a reason for limited lymphatic resection in malignant disease.

Chyle↗
PubMed1988

[Hyperimmunoglobulin treatment in CMV infections following heart transplantation].

Clinically manifest cytomegalovirus (CMV) infections, with and without pulmonary involvement, occurred in two patients after heart transplantation. The diagnosis was confirmed immunologically. After administration of CMV hyperimmunoglobulin and prophylactic antibiotics and a reduction of immunosuppressives, rapid clinical improvement ensued so that both patients were discharged from hospital after seven and ten days, respectively.

Adolescent↗
PubMed1988

Hyperimmuneglobulin for cytomegalovirus prophylaxis following heart transplantation.

Cytomegalovirus continues to be an important cause of morbidity and mortality following organ transplantation. In a series of 75 heart transplant patients, we have compared two protocols for prophylactic administration of CMV hyperimmuneglobulin. The first group of patients received immunoglobulin on the operative and on the tenth postoperative days. The second group of patients received immunoglobulins on the operative day, and repeatedly with each period of increased immunosuppression. With repeated doses of immunoglobulin prophylaxis, the incidence of CMV reactivation and the clinical severity of CMV infection were both significantly reduced. A reduction in the incidence of CMV infection in recipients who were seronegative preoperatively was also observed. (5/8 vs. 7/25 patients; P = 0.06). We conclude that repeated administration of specific hyperimmuneglobulin with each period of increased immunosuppression following heart transplantation has a beneficial effect on both CMV reactivation and infection.

Adult↗
PubMed1988

[Value of sonography in the preoperative staging of stomach cancer].

In 51 patients with histologically proven gastric carcinoma ultrasonography of the abdomen for the preoperative staging was performed. The primary tumor was found by sonography in 73% of the cases. Only 40% of the lymph-node metastases could be detected. Ultrasonography as a non-invasive procedure is an usefull examination for the preoperative diagnosis of gastric carcinoma, especially concerning extraluminal tumor extension. Explorative laparotomy, however, for the determination of the local resectability can not be avoided by ultrasonography.

Female↗
PubMed1988

[Ultrasonic morphology of the normal Achilles tendon and pattern of pathological changes].

The anatomical structure of the Achilles tendon causes a fibrillary echo texture with fine, parallel echogenic lines. The peritendineum outlining the tendon can be delineated. Achilles tendon ruptures can easily be detected by ultrasound, as can the structural changes in achillodynia. The typical sonographic patterns of rupture of the Achilles tendon and achillodynia are demonstrated.

Achilles Tendon↗
PubMed1988

[Sonography of the shoulder joint. Study technic, sonomorphology and diagnostic significance].

In the evaluation of the impingement syndrome, conventional radiography can only show secondary bony changes. Sonography is able to demonstrate the anatomy of the musculotendinous structure of the rotator cuff. Lesions can be detected with the same accuracy and specificity as by contrast arthrography. As sonography is a non-invasive method, it should be used routinely to test rotator cuff integrity. Joint effusions and proliferative synovial changes are easily demonstrated by sonography. It is thus possible to perform follow-up studies in a pre-erosive stage of rheumatoid arthritis.

Humans↗
PubMed1988

Multi-centre evaluation of the Behring ELISA Processor II.

A multi-centre evaluation of the Behring ELISA Processor II in connection with the Enzygnost-tests from Behringwerke was performed by 3 laboratories following the ECCLS Guidelines for the Evaluation of Analysers in Clinical Chemistry. The performance characteristics were studied with analytical tests for anti-HBs1), HBsAg and anti-CMV2). This evaluation represents, to our knowledge, the first trial in clinical virology with guidelines primarily designed for clinical chemistry. The evaluation revealed that the highly automated Behring ELISA Processor II is a reliable tool in the virological laboratory. The data obtained showed low imprecision and good accuracy. The washing unit proved to be very efficient. No carry-over of reagents was detected in the dispenser system. Several improvements for further developments of the analyser are suggested. This multi-centre study has shown that the ECCLS protocol can be used to evaluate analysers and test systems in clinical virology.

Autoanalysis↗
PubMed1987

[Frequency and serologic diagnosis of cytomegalic infections following heart transplantation in 1986].

Of 60 patients receiving heart transplants in 1986, 45 were examined serologically for at least 50 days: 28 had a cytomegalovirus (CMV) infection and 12 had symptoms of a CMV infection. In those patients who before transplantation were serological negative for CMV but had received organs from CMV-IgG positive donors, the incidence of the disease was highest. No CMV infection was observed among CMV-IgG negative recipients of CMV-negative donor hearts.

Adolescent↗
PubMed1987

[Transient HIV-antibody positive tests in heart transplantation patients after repeated administration of a CMV immune globulin preparation].

After repeated administration of relatively high doses of a cytomegalovirus immunoglobulin preparation to two patients after heart transplantation, both the ELISA and the immuno-blot tests became temporarily positive (for 21 and 41 days, respectively) to HIV antibodies. The CMV immunoglobulin preparation was demonstrated to have high HIV antibody titres. The latter ran parallel to antibody titres against measles virus, also transferred passively with the immunoglobulin preparation. This makes it unlikely that HIV antibodies had been formed by active immunization from HIV in the immunoglobulin preparation. Within 126 and 176 days, respectively, after the last positive test against HIV antibodies there was no further demonstration of HIV antibodies or of a corresponding illness. There was thus no evidence of an HIV infection having been transmitted by the immunoglobulin preparation.

Antibodies, Viral↗