PubMed Health⌕ Search

Biomedical subjects

H Moskowitz

Publications and source records attributed to H Moskowitz.

At least 55 records · Page 3Linked to original sources
PubMed1983

Clinical utilization of perfusion lung scans in the diagnosis of pulmonary emboli.

To study the utilization of perfusion lung scans, the records of 116 consecutive patients who had "pulmonary embolus" (PE) as a discharge diagnosis were reviewed. The PE group was identical to the control group in the percent of male patients and of white patients. However, the PE group was older (60.4 versus 47.5 years), had a higher percentage of smokers (53.1 versus 34), and had a higher proportion of obese individuals (39.6 versus 25) than controls. Mortality was significantly greater in the PE patients (9.5% versus 1%) as was the length of hospital stay (21 versus 9 days). The PE group had more chest x-rays than did controls (6.1 versus 1.8) and had a higher percentage of lung scans (95.7 versus 5). While 95.7% of the patients diagnosed as having PE were studied by perfusion lung scans, 4.3% had none. Further, 18.1% had only one lung scan. Of 111 patients with perfusion lung scans, 3.6% were discharged with a diagnosis of PE despite a negative study. While clinical acceptance of perfusion lung scans is high, some patients diagnosed as having pulmonary emboli did not have a scan but underwent other diagnostic tests, while a small group of others were assigned the diagnosis despite a negative lung scan. This points to the need for better communication with referring clinicians.

Anticoagulants↗
PubMed1982

Effects of chronically administered buspirone and diazepam on driving-related skills performance.

The effects on driving skills of buspirone and diazepam, singly and in combination with alcohol, were examined. Three groups of 16 subjects each (8 men and 8 women) received either 20 mg of buspirone, 15 mg of diazepam, or placebo daily for 9 days. On day 9, they also received alcohol (men, 0.85 g/kg; women, 0.72 g/kg). On days 1, 8, and 9, subjects were tested on a driving simulator and given four sessions of divided attention tasks examining tracking and visual search performance. Extensive evidence of performance impairment associated with diazepam contrasted with improved performance under chronic buspirone treatment. Alcohol effects were additive.

Adult↗
PubMed1980

Effects of diphenhydramine and alcohol on skills performance.

Twelve men were subjects in a repeated measures experiment on the effects on performance of diphenhydramine, alcohol, and diphenhydramine and alcohol in combination. Behavioral measures included compensatory tracking, a divided attention task, information processing rate, and critical tracking. Performance impairment occurred under all treatments with an additive effect under the combined drug-alcohol treatment.

Adult↗
PubMed1979

Effect of alcohol and marijuana on eye movements.

The effects of alcohol and marijuana (tetrahydrocannabinol-THC) on saccades, smooth pursuit, and optokinetic nystagmus were quantitatively evaluated in 24 normal subjects using electro-oculographic recordings. Each subject was given an initial trial run and then tested three times (at weekly intervals) with either 0.0microgram THC or 100 microgram THC/kg bodyweight while at three different blood alcohol concentrations (0.0, 0.05 and 0.1%). A 2X3 factorial design was used. Saccades and smooth pursuit were induced by a dot of light moving in steps and ramps on a modified television set. Optokinetic nystagmus was induced by a cloth drum completely surrounding the subject and moving at a constant velocity of 30 degrees/s. Alcohol (0.05 and 0.1%) alone produced significant (p less than 0.05) impairment of saccade maximum velocity and reaction time, smooth pursuit velocity, and optokinetic slow-component velocity. The addition of THC caused performance to further deteriorate at each blood alcohol level but, in all but one instance, the added effect was not statistically significant ( greater than 0.05). At the THC and alcohol concentrations used in this study, the eye movement effects of alcohol over-shadowed those of marijuana.

Adult↗
PubMed1977

Prognostic significance of portal pressure in patients with bleeding esophageal varices.

Portal pressure was determined in 76 patients during acute bleeding varices, and the degree of portal hypertension was related to the cessation or noncessation of hemorrhage with nonoperative management. A direct relationship between the severity of hemorrhage and the degree of portal hypertension was established. It is suggested that portal pressure be determined as soon as feasible when bleeding varices are suspected and that other causes of hemorrhage be carefully excluded. The obtained data are of great prognostic significance and might be helpful in planning the course of therapy in these individuals.

Adult↗
PubMed1976

Decrease of iconic memory after alcohol.

Alcohol did not alter the rate of information loss from iconic memory. However, there was a dose-related decrease in the total amount of information reported which was independent of the rate of information loss.

Adult↗