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Biomedical subjects

H Mosnier

Publications and source records attributed to H Mosnier.

At least 55 records · Page 3Linked to original sources
PubMed1990

[Adenocarcinoma of the duodenum. 17 cases].

Seventeen cases of duodenal adenocarcinoma are reported and compared with cases from the literature. Ten tumours were located in the second part of the duodenum, 9 were around the hepatopancreatic ampulla, 4 were above and 4 below this ampulla. Four tumours (23 per cent) had limited intramural expansion (Dukes' stage A or B) and 6 (35 per cent) involved the lymph nodes. The major clinical signs were loss of weight (11 cases), signs of obstruction (9 cases), bleeding (6 cases) and jaundice (6 cases). The paraclinical examinations that were determinant for the diagnosis were gastroduodenal radiographic study (16 cases) and endoscopy with biopsy (9 cases). Computerized tomography was useful for preoperative evaluation. The respective values of these examinations for early diagnosis and excisability of these tumors are discussed. All 17 patients were operated upon: 11 (64.7 per cent) underwent radical excision, 5 had duodenal bypass and 1 had exploratory laparotomy. The overall operative mortality rate was 5.8 per cent, with no deaths for bypasses and excisions. Mean survival after bypass was 5 1/2 months. The one year survival was 63.5 per cent in 5 patients with excision and 83.3 per cent in 6 patients with cephalic duodenopancreatectomy, but none of these patients survived for more than 5 years.

Adenocarcinoma↗
PubMed1990

[Anal metastases from cancer of the colon].

Two cases of anal metastases from sigmoid carcinoma are reported. The two patients were treated by local excision. The various mechanisms of tumoral spread are discussed from a review of the literature; the most frequent mechanism is cellular exfoliation. The most commonly used therapeutic approach is local excision combined, if necessary, with reconstruction of the sphincters.

Adenocarcinoma↗
PubMed1990

Endorectal sonography in the management of rectal villous tumours.

Thirty-seven patients with rectal villous tumours were investigated by endorectal sonography to assess the integrity of the rectal muscularis propria at the tumour level. In four cases assessment of invasion was impossible. In 24 patients, endosonography revealed an ultrasonically superficial lesion not infiltrating the muscular layer. This was confirmed either, in the case of laser treatment, by the absence of malignant recurrence during the follow-up period or by histological examination after surgical resection. In nine patients, endosonography showed infiltration of the muscular layer. This was histologically confirmed in five operated patients. In the remaining four, laser destruction was performed: in two, a rectal adenocarcinoma was present 3 and 6 months later, respectively. These findings show that endosonography has a place in the management of rectal villous tumours, demonstrating invasive cancer in cases where other forms of assessment were wrongly reassuring.

Adenocarcinoma↗
PubMed1990

[33 cases of hematoma of the rectus abdominis muscle in a surgical department].

The authors report a series of 33 hematomas of the recti-abdominis muscles from a surgery department: 15 occurred under anticoagulants 6 were spontaneous, 5 followed trauma and 6 a surgical procedure. The clinical picture was subacute in 24 cases, combining an abdominal pain (32 cases) a mass (10 cases) and an extensive ecchymosis (6 cases). The picture was acute in 6 extensive hematomas with collapse and anemia. In 3 cases an isolated mass was the first symptom. Echography has represented, since 1977, a decisive advance in the diagnosis, which was found to be accurate in 5 out of 10 cases before its introduction, and in 19 out of 20 when it was resorted to in the 23 cases recorded later. TDM is useful only in few cases. 23 patients were have been operated on: 6 for cardiovascular collapse, 3 because the diagnosis had not been made, 8 on order to confirm the diagnosis, 3 because of an increase in size of the hematoma and 3 owing to infection. In the 10 cases not submitted to surgery, the evolution was favourable. The therapeutic approach must be lanced according to the patient's condition, the size, side effect and evolution of hematoma. The aim of the operation is to evacuate the hematoma, to drain it and sometimes to tie up the bleeding vessel.

Abdominal Injuries↗
PubMed1989

[Treatment of complicated peptic esophagitis. Role of total duodenal diversion].

Total duodenal diversion was performed in 60 patients with reflux oesophagitis complicated by stricture, brachyoesophagus, endobrachyoesophagus or previous oesophago-gastric surgery. The standard operation (truncal vagotomy, antrectomy, 70 cm Roux-en Y anastomosis) was carried out in 41 patients; technical adjustments were necessary in 19 patients previously operated. One patient died of post-operative pulmonary embolism. Lasting cure of the oesophagitis was obtained within less than 3 months in 56/59 patients (93 per cent). Three-hour post-prandial pH measurements showed control of the reflux in 48/52 patients (92 p. 100). Anastomotic ulcers developed in 3 patients who did not have vagotomy. One case of complete remission of endobrachyoesophagus was observed, and 4 cases are now in partial remission. Digestive tract sequelae were found in 9 patients who had undergone surgery, but they were disabling in only one of these. These results suggest that total duodenal diversion is a suitable treatment of complicated reflux oesophagitis.

Adult↗
PubMed1989

[Mirizzi's syndrome].

Six cases of Mirizzi syndrome are reported. The syndrome consists of a special anatomical variant of the cystic duct, which has a low opening but runs side-by-side with the common bile duct, associated with entrapment of a gallstone in the cystic duct or the neck of the gallbladder, partial or total obstruction of the hepatic duct by the stone and by inflammatory lesions, and recurrent cholangitis. Clinical signs are non-specific and suggest at first sight an obstructive jaundice. Pre-operative morphological examination seldom provide a diagnosis before surgery. In the most typical cases ultrasonography shows dilatation of the upper biliary tract with narrowing of the hepatic duct below the dilatation, due to a stone located outside the common bile duct. Opacification of the biliary tract by endoscopic retrograde catheterization of the papilla duodeni or by transparietohepatic puncture give suggestive images (non-opacification of the cystic duct, narrowing of the hepatic duct opposite the extrinsic compression, with overlying dilatation), but these images are not specific. The per-operative diagnosis is difficult owing to the inflammatory lesions, and a diagnosis of cholangiocarcinoma may be envisaged. Cholecystectomy with recanalization of the cystic duct suppresses the extrinsic compression and helps the inflammatory lesions to regress. However, opening and draining the common bile duct is often necessary.

Adult↗
PubMed1989

[Emergency surgery of left colonic occlusion].

The authors have reported 61 emergency cases of left-sided colonic obstruction recorded over a period spanning for ten years. The observations break down showed that 44 patients had carcinoma of the colon; 9 presented with volvulus; 4 with diverticulitis; 1 with ischemic colitis, and 3 suffered from Ogilvie's syndrome. Surgical procedures, associated or not with cure, included colostomy (30 cases), colonoscopic detorsion (8 cases), resection (22 cases). The overall morbidity and mortality rates were 26% and 13%, respectively.

Acute Disease↗
PubMed1989

[Extracorporeal lithotripsy of gallbladder calculi. Tolerability, complications and early results].

The purpose of this prospective study, conducted on 88 patients, was to assess the tolerance, efficiency and early complications due to a piezo-electric lithotriptor in the destruction of gallbladder stones. One hundred and sixty one sessions were performed in 82 patients. All patients had symptomatic, uncomplicated lithiasis, the diameter of which was less than, or equal to, 30 mm. All patients had less than 7 stones in a functional gallbladder. In 22 patients, the stones were calcified. Lithotripsies were carried out without anesthesia or premedication, except in an 8-year-old child who had to be anesthetized. In 3 cases it was impossible to visualize the gallstones and in 3 other patients, the procedure was discontinued because of abdominal pain. Following the procedure, biliary pain occurred in 20 per cent of the patients. One patient only had biliary colic with transient anicteric cholestasis. Clinical examination, sonography, biological tests were found to be normal in all other patients. Endoscopic sphincterotomy or emergency surgery was never required. Stones were found to be unaltered in 6 patients following 2 lithotripsy sessions. The 76 other patients had fragmentation of their stones. The free gallbladder rate was 15.8 per cent between 0 and 2 months, 24.6 per cent between 2 and 4 months and 51.3 per cent between 4 and 8 months. These results tend to show that the destruction of biliary stones by piezo-electric lithotriptor is efficient and well tolerated. As repeated routine examinations were always negative, the three-day hospitalisation period no longer seems necessary.

Adolescent↗
PubMed1987

[Endorectal ultrasonography: evaluation of locoregional extension of cancers of the rectum].

The treatment of rectal carcinoma is mainly determined by its local extension, which is difficult to assess before surgery. Our purpose was to determine the reliability of endorectal echography (ERE) in order to provide preoperative assessment of local extension of rectal tumors. Twenty-five patients with rectal adenocarcinoma were included in this study. Seventeen tumors could be felt by rectal examination. ERE was impossible in one case. Echographic data were compared with anatomic findings in 24 patients. ERE provided an accurate assessment of the parietal involvement in 22 cases. The sensitivity and specificity of ERE in determining the spread of the tumor to the rectum alone were 1 and 0.89, respectively, superior to the results provided by clinical examination alone (sensitivity 0.84-specificity 0.76). When the results of the two investigations were identical, all patients were well classified. For lymph node involvement, the sensitivity and specificity of ERE were 0.71 and 0.76 respectively. These results show that ERE is one of the best investigations currently available for assessing parietal involvement of rectal tumors. ERE might be able to determine the appropriate place of radiation therapy, local excision or anal sphincter preservation.

Adenocarcinoma↗
PubMed1986

[Epidermoid cancer of the thoracic esophagus following mediastinal irradiation].

Squamous cell carcinoma of the esophagus induced by radiation therapy is a rare entity. We report 4 cases observed during the past 4 years. Three women and one man aged from 47 to 78 years developed squamous cell carcinoma of the esophagus 8 to 11 years after radiation therapy. The 3 women had been irradiated for breast cancer and the man for Hodgkin's disease with 40 to 57.5 Gy. Three patients were operated on and the immediate postoperative course was uneventful. Culling data from this report and from the literature we reviewed the different steps concerning the diagnosis and the treatment of this complication of radiation therapy. We suggest that diagnostic and therapeutic modalities should follow the same guidelines as in other esophageal cancers.

Aged↗
PubMed1985

[Long-term surveillance of patients operated on for colorectal cancers].

Patients who have undergone curative surgical treatment for colo-rectal cancer require long term follow-up in order to detect polyps or new neoplastic colo-rectal lesions and any signs of metastases or loco-regional recurrence. In this way, it is possible to prevent the development of new colo-rectal cancers by means of polypectomy. Furthermore, early detection of recurrence of the initial neoplasm appears to be effective, provided that the patients are followed rigorously and that the recurrence is detected at a stage at which re-operation can ensure long term survival.

Colonic Neoplasms↗
PubMed1983

[Acute gangrenous acalculous cholecystitis disclosed by postoperative septic shock].

Three cases of acute gangrenous acalculous cholecystitis, revealed by a postoperative septic shock, are reported. Clinical examination was negative and the surgery gave the diagnosis. Infection with biliary stasis and ischaemia accounts for this pathological entity. The very serious prognosis of this condition can only be reversed by cholecystectomy.

Acute Disease↗