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Biomedical subjects

H Muta

Publications and source records attributed to H Muta.

32 records · Page 2Linked to original sources

Endoscopic ultrasonography findings in acute gastric anisakiasis.

To clarify the components of the thickened gastric wall in acute gastric anisakiasis, we evaluated endoscopic ultrasonography (EUS) findings of acute gastric anisakiasis. Ten patients with acute gastric anisakiasis underwent endoscopic ultrasonography immediately after anisakiasis was diagnosed by endoscopy. In the acute phase of gastric anisakiasis, endoscopic ultrasonography (EUS) detected a thickening of the gastric wall made of mainly thickened third layer with low echoic changes. When EUS was performed 7 to 11 days later in seven patients, the EUS findings had normalized. We made clear EUS findings in acute gastritis due to gastric anisakiasis. Consequently, we found, by EUS, that the main inflammatory lesion in anisakiasis was in the submucosal layer of gastric wall.

Acute Disease↗

A pitch-synchronous analysis of hoarseness in running speech.

A method of pitch-synchronous acoustic analysis of hoarseness requiring a voice sample of only four fundamental periods is presented. This method calculates a noise-to-signal (N/S) ratio, which indicates the depth of valleys between harmonic peaks in the power spectrum. The spectrum is calculated pitch synchronously from a Fourier transform of the signal, windowed through a continuously variable Hanning window spanning exactly four fundamental periods. A two-stage procedure is used to determine the exact duration of the four fundamental periods. An initial estimate is obtained using autocorrelation in the time domain. A more precise estimate is obtained in the frequency domain by minimizing the errors between the preliminary calculated power spectrum and the predicted spectrum spread of a windowed harmonic signal. Analysis of synthesized voices showed that the N/S ratio is sensitive to additive noise, jitter, and shimmer, and is insensitive to slow (8 Hz) modulation in fundamental frequency and amplitude. An analysis of pre- and postoperative voices of six patients with benign laryngeal disease showed that the N/S ratio for vowel /u/ in running speech consistently improved after surgery for all subjects, in agreement with their successful therapeutic results.

Hoarseness↗

Malignant neurofibroma with glandular differentiation (glandular schwannoma).

A case of malignant shwannoma is reported with unusual elements in an 89-year-old female. A large mass was located in the subcutaneous tissue of the right lateral chest wall and measured 5 cm in the greatest diameter. Histologically the tumor was composed of neurofibroma and malignant schwannoma with glandular differentiation. Neurofibroma characterized by numerous hyaline neural nodules was located in the peripheral portion of the tumor, whereas malignant schwannoma occupied a large part of the central portion of the tumor. The glandular elements observed in some areas of malignant schwannoma consisted of cuboidal and columnar shaped cells and were arranged in tubular or tubulo-medullary fashion in which rosettes or pseudorosettes were found. Mucicarminophilic material was observed, both in the cytoplasm and in the lumen. Seven reported cases of peripheral nerve tumor with glandular differentiation are reviewed briefly.

Aged↗

Gastric teratoma of children--a case report with review of the literature.

A case of gastric teratoma in a 3-month-old male infant is reported. A large mass showing endogastric growth was located on the lesser curvature of cardiac region and measured 6.5 X 5 X 4 cm. Histologically the tumor was composed of the elements derived from three germ layers including squamous, cuboidal and high columnar epithelium with or without cilia, fat tissue, smooth muscle, cartilage and neural tissue. Large parts of these elements appeared to be predominantly mature but some of the neural tissue showed primitive immature structures. Forty-four reported cases of gastric teratoma were briefly reviewed.

Humans↗

Fine structural comparison of Ewing's sarcoma with neuroblastoma.

Two cases of Ewing's sarcoma and two neuroblastoma, rosette forming and round cell type, were studied electron microscopically and their fine structures were compared. The neoplastic cells of Ewing's sarcoma were characterized by aggregated glycogen particles in the cytoplasm. They had pseudopod-like cytoplasmic processes having tight junctions, which never contained microtubules or mitochondria. Ewing's sarcoma cells exhibited several stages of cell maturation and some mature cells possessed a large amount of smooth and rough endoplasmic reticulum, large Golgi complexes and numerous phagosomes containing glycogen particles as well as cytoplasmic organelles. The neoplastic cells of neuroblastoma, rosette forming type, were characterized by synaptic junctions and numerous cytoplasmic processes with production of neurites containing microtubules, neurofibrils, mitochondria and a few catecholamine granules. A few cytoplasmic processes containing mitochondria were observed even in the round cell type.

Adolescent↗

Serum sodium levels in patients with Kawasaki disease.

The purpose of this study was to assess the hypothesis that lower serum sodium levels are associated with cardiovascular sequelae in patients with Kawasaki disease (KD). We used the database of the 16th nationwide survey of KD in Japan. We investigated the distribution of serum sodium levels and the relationship between serum sodium levels and cardiovascular sequelae. Of the reported cases, serum sodium levels were reported in 13,569 patients (89%). The proportion of patients with serum sodium levels 130 mEq/L or less, was greater in complete cases than in incomplete cases. The proportion of patients with serum sodium levels 130 mEq/L or less was increased with age. The largest proportion of patients with serum sodium levels 130 mEq/L or less was found in the category of 3-5 days since onset of illness. A serum sodium of level 135 mEq/L or less was an independent risk factor for cardiovascular sequelae (odds ratio, 1.79, 95% confidence interval, 1.42-2.26). Among patients with KD, there are significant differences in serum sodium levels between diagnostic categories, age, and days since the onset of illness. The sodium level may be a simple predictor of cardiovascular sequelae.

Biomarkers↗

Quantitation of the global right ventricular function in children with normal heart and congenital heart disease: a right ventricular myocardial performance index.

Although the assessment of right ventricular (RV) function is important in the clinical management of children with congenital heart disease, available imaging techniques have been limited because of the complex geometry of the right ventricle. A new Doppler index combining systolic and diastolic time intervals (the Tei index) has been reported to be useful for the assessment of global RV function in adults. However, normal values in children, age-related changes, and the clinical utility of the Tei index with regard to congenital heart disease have not been demonstrated. The purpose of this study was to prospectively assess RV function in children with normal heart and congenital heart disease using the Tei index. The subjects included 150 healthy children and 43 patients with congenital heart disease (35 patients with atrial septal defects and 8 patients who had had a Senning operation). The index was defined as the sum of isovolumetric contraction time and isovolumetric relaxation time divided by ejection time and was measured from conventional RV outflow and inflow Doppler velocity profiles. The Tei index was not affected by age in healthy children (0.24 +/- 0.04). There was a significant difference in index rating between patients who had had a Senning operation (0.58 +/- 0.09) and healthy children (p < 0.01), but there was no significant difference between children with atrial septal defect (0.25 +/- 0.13) and healthy children. The Tei index is a feasible approach to use when assessing global RV function in children with congenital heart disease.

Adolescent↗

Selection of video cameras for stroboscopic videolaryngoscopy.

Stroboscopic evaluation for the analysis of laryngeal function and disease has been reemphasized recently and its routine clinical use recommended. Many have found, however, that it is not always possible to obtain consistently satisfactory video images of stroboscopic laryngoscopy. The problem is related to the low intensity of the xenon light source during stroboscopy. The authors have tried many different video cameras available, along with the Brüel & Kjaer Rhino-Larynx Stroboscope type 4914, and two types of endoscopes (flexible and rigid). The cameras included 1) single tube camera, 2) single chip metal oxide semiconductors (MOS) solid-state camera, 3) single chip charge-coupled devices (CCD) solid-state camera, 4) three-tube camera, and 5) three-chip CCD camera. Currently available video cameras and their adaptability for stroboscopic videolaryngoscopy are discussed.

Equipment Design↗